The K526R substitution in viral protein PB2 enhances the effects of E627K on influenza virus replication.
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Novel Polymerase Gene Mutations for Human Adaptation in Clinical Isolates of Avian H5N1 Influenza VirusesOne health, multiple challenges: The inter-species transmission of influenza A virusInfluenza A virus transmission via respiratory aerosols or droplets as it relates to pandemic potentialUse of highly pathogenic avian influenza A(H5N1) gain-of-function studies for molecular-based surveillance and pandemic preparedness.Viral dominance of reassortants between canine influenza H3N2 and pandemic (2009) H1N1 viruses from a naturally co-infected dog.Multiple Natural Substitutions in Avian Influenza A Virus PB2 Facilitate Efficient Replication in Human CellsRapid acquisition of polymorphic virulence markers during adaptation of highly pathogenic avian influenza H5N8 virus in the mouseA family cluster of three confirmed cases infected with avian influenza A (H7N9) virus in Zhejiang Province of China.Global and quantitative proteomic analysis of dogs infected by avian-like H3N2 canine influenza virus.Genetic Characterization of Highly Pathogenic Avian Influenza (H5N8) Virus from Domestic Ducks, England, November 2014Genomic Signatures for Avian H7N9 Viruses Adapting to Humans.An A14U Substitution in the 3' Noncoding Region of the M Segment of Viral RNA Supports Replication of Influenza Virus with an NS1 Deletion by Modulating Alternative Splicing of M Segment mRNAsFrequency of influenza H3N2 intra-subtype reassortment: attributes and implications of reassortant spread.Suboptimal Humoral Immune Response against Influenza A(H7N9) Virus Is Related to Its Internal Genes.PB2-588 V promotes the mammalian adaptation of H10N8, H7N9 and H9N2 avian influenza virusesComplete Genome Sequences of an H5N1 Highly Pathogenic Avian Influenza Virus Isolated from Pigeon in China in 2012Characterization of the Pathogenesis of H10N3, H10N7, and H10N8 Subtype Avian Influenza Viruses Circulating in Ducks.An NS-segment exonic splicing enhancer regulates influenza A virus replication in mammalian cells.Genetic Adaptation of Influenza A Viruses in Domestic Animals and Their Potential Role in Interspecies Transmission: A Literature Review.Prerequisites for the acquisition of mammalian pathogenicity by influenza A virus with a prototypic avian PB2 gene.Characterization of reassortant H1-subtype avian influenza viruses isolated from poultry in Zhejiang Province in China from 2013 to 2015.Genetic and molecular characterization of a novel reassortant H2N8 subtype avian influenza virus isolated from a domestic duck in Zhejiang Province in China.Isolation and molecular characterization of reassortant H11N3 subtype avian influenza viruses isolated from domestic ducks in Zhejiang Province in China.Synergistic effect of PB2 283M and 526R contributes to enhanced virulence of H5N8 influenza viruses in miceA Highly Pathogenic Avian H7N9 Influenza Virus Isolated from A Human Is Lethal in Some Ferrets Infected via Respiratory Droplets.Molecular Markers for Interspecies Transmission of Avian Influenza Viruses in Mammalian Hosts.Amino Acid Substitutions HA A150V, PA A343T, and PB2 E627K Increase the Virulence of H5N6 Influenza Virus in Mice.New threats of H7N9 influenza virus: the spread and evolution of highly and low pathogenic variants with high genomic diversity in Wave Five.Large-scale sequence analysis reveals novel human-adaptive markers in PB2 segment of seasonal influenza A viruses.Multiple polymerase gene mutations for human adaptation occurring in Asian H5N1 influenza virus clinical isolatesAttenuation of highly pathogenic avian influenza A(H5N1) viruses in Indonesia following the reassortment and acquisition of genes from low pathogenicity avian influenza A virus progenitorsZoonotic Potential of Influenza A Viruses: A Comprehensive OverviewThe Pandemic Threat of Emerging H5 and H7 Avian Influenza VirusesBroad neutralizing activity of a human monoclonal antibody against H7N9 strains from 2013 to 2017
P2860
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P2860
The K526R substitution in viral protein PB2 enhances the effects of E627K on influenza virus replication.
description
2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
The K526R substitution in vira ...... n influenza virus replication.
@ast
The K526R substitution in vira ...... n influenza virus replication.
@en
The K526R substitution in vira ...... n influenza virus replication.
@nl
type
label
The K526R substitution in vira ...... n influenza virus replication.
@ast
The K526R substitution in vira ...... n influenza virus replication.
@en
The K526R substitution in vira ...... n influenza virus replication.
@nl
prefLabel
The K526R substitution in vira ...... n influenza virus replication.
@ast
The K526R substitution in vira ...... n influenza virus replication.
@en
The K526R substitution in vira ...... n influenza virus replication.
@nl
P2093
P2860
P356
P1476
The K526R substitution in vira ...... n influenza virus replication.
@en
P2093
Bobo Wing-Yee Mok
Honglin Chen
Lanjuan Li
Shigui Yang
Siu-Ying Lau
Wai-Lan Wu
Wenjun Song
Xiaofeng Huang
P2860
P2888
P356
10.1038/NCOMMS6509
P407
P577
2014-11-20T00:00:00Z
P5875
P6179
1001717447