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Interplay of ryanodine receptor distribution and calcium dynamics

Interplay of ryanodine receptor distribution and calcium dynamics

http://www.wikidata.org/entity/Q34680310

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Examination of the Effects of Heterogeneous Organization of RyR Clusters, Myofibrils and Mitochondria on Ca2+ Release Patterns in Cardiomyocytes Numerical analysis of Ca2+ signaling in rat ventricular myocytes with realistic transverse-axial tubular geometry and inhibited sarcoplasmic reticulum Multiscale modeling in rodent ventricular myocytes Three-dimensional distribution of ryanodine receptor clusters in cardiac myocytes Analysis of ryanodine receptor clusters in rat and human cardiac myocytes Three-dimensional electron microscopy reveals new details of membrane systems for Ca2+ signaling in the heart.Subcellular calcium dynamics in a whole-cell model of an atrial myocyte.Modeling effects of L-type ca(2+) current and na(+)-ca(2+) exchanger on ca(2+) trigger flux in rabbit myocytes with realistic T-tubule geometries Hierarchical clustering of ryanodine receptors enables emergence of a calcium clock in sinoatrial node cells.New software developments for quality mesh generation and optimization from biomedical imaging data A new approach to the detection and statistical classification of Ca2+ sparks Differential sensitivity of Ca²+ wave and Ca²+ spark events to ruthenium red in isolated permeabilised rabbit cardiomyocytes.Dantrolene suppresses spontaneous Ca2+ release without altering excitation-contraction coupling in cardiomyocytes of aged mice.Nonlinear and Stochastic Dynamics in the Heart Cellular cartography.Identification and characterization of calcium sparks in cardiomyocytes derived from human induced pluripotent stem cells.Variations in local calcium signaling in adjacent cardiac myocytes of the intact mouse heart detected with two-dimensional confocal microscopy.SERCA2a gene transfer decreases sarcoplasmic reticulum calcium leak and reduces ventricular arrhythmias in a model of chronic heart failure.Tachycardia-induced silencing of subcellular Ca2+ signaling in atrial myocytes.Multiscale modeling of calcium dynamics in ventricular myocytes with realistic transverse tubules A localized meshless approach for modeling spatial-temporal calcium dynamics in ventricular myocytes.Hybrid stochastic and deterministic simulations of calcium blips.Three-dimensional distribution of cardiac Na+-Ca2+ exchanger and ryanodine receptor during development.Criticality in intracellular calcium signaling in cardiac myocytes Eavesdropping on the social lives of Ca(2+) sparks Calcium alternans in a couplon network model of ventricular myocytes: role of sarcoplasmic reticulum load.Ryanodine receptor cluster fragmentation and redistribution in persistent atrial fibrillation enhance calcium release.Calcium alternans in cardiac myocytes: order from disorder.Synchrony of cardiomyocyte Ca(2+) release is controlled by T-tubule organization, SR Ca(2+) content, and ryanodine receptor Ca(2+) sensitivity.Calsequestrin-mediated mechanism for cellular calcium transient alternans Ryanodine receptor-mediated arrhythmias and sudden cardiac death.Sensitivity of rabbit ventricular action potential and Ca²⁺ dynamics to small variations in membrane currents and ion diffusion coefficients.Parallel acceleration for modeling of calcium dynamics in cardiac myocytes Three-dimensional geometric modeling of membrane-bound organelles in ventricular myocytes: bridging the gap between microscopic imaging and mathematical simulation.Dynamic local changes in sarcoplasmic reticulum calcium: physiological and pathophysiological roles.Decoding myocardial Ca²⁺ signals across multiple spatial scales: a role for sensitivity analysis.Ca²⁺ waves in the heart.A computational model of spatio-temporal cardiac intracellular calcium handling with realistic structure and spatial flux distribution from sarcoplasmic reticulum and t-tubule reconstructions.Studying dyadic structure-function relationships: a review of current modeling approaches and new insights into Ca2+ (mis)handling.Mechano-chemo-transduction in cardiac myocytes.

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P2860

Interplay of ryanodine receptor distribution and calcium dynamics

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2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2006年论文

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Interplay of ryanodine receptor distribution and calcium dynamics

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Interplay of ryanodine receptor distribution and calcium dynamics

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Interplay of ryanodine receptor distribution and calcium dynamics

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Interplay of ryanodine receptor distribution and calcium dynamics

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Interplay of ryanodine receptor distribution and calcium dynamics

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Interplay of ryanodine receptor distribution and calcium dynamics

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C William Balke

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John N Shadid

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Leighton T Izu

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Shawn A Means

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Ye Chen-Izu

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P2860

Mutations in the genes for cardiac troponin T and alpha-tropomyosin in hypertrophic cardiomyopathy

Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle

Dynamic regulation of sarcoplasmic reticulum Ca(2+) content and release by luminal Ca(2+)-sensitive leak in rat ventricular myocytes.

Predetermined recruitment of calcium release sites underlies excitation-contraction coupling in rat atrial myocytes

Large currents generate cardiac Ca2+ sparks.

Activation and propagation of Ca(2+) release during excitation-contraction coupling in atrial myocytes

Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy

Three-dimensional distribution of ryanodine receptor clusters in cardiac myocytes

Ca(2+) transients and Ca(2+) waves in purkinje cells : role in action potential initiation.

Ca2+ blinks: rapid nanoscopic store calcium signaling

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