Immunoglobulin A antibodies against ricin A and B subunits protect epithelial cells from ricin intoxication
about
Secretory IgA's complex roles in immunity and mucosal homeostasis in the gutSub-domains of ricin's B subunit as targets of toxin neutralizing and non-neutralizing monoclonal antibodiesIntroduction of a disulfide bond leads to stabilization and crystallization of a ricin immunogenStructure of RiVax: a recombinant ricin vaccineBaicalin inhibits the lethality of ricin in mice by inducing protein oligomerization.Characterization of a novel high-affinity monoclonal immunoglobulin G antibody against the ricin B subunit.A monoclonal immunoglobulin G antibody directed against an immunodominant linear epitope on the ricin A chain confers systemic and mucosal immunity to ricin.Localization of non-linear neutralizing B cell epitopes on ricin toxin's enzymatic subunit (RTA)Microbiota activation and regulation of innate and adaptive immunity.Mice deficient in intestinal epithelium cytochrome P450 reductase are prone to acute toxin-induced mucosal damage.Neutralising antibodies against ricin toxin.Recognition of secretory IgA by DC-SIGN: implications for immune surveillance in the intestineFolding domains within the ricin toxin A subunit as targets of protective antibodiesHumanization and characterization of an anti-ricin neutralization monoclonal antibodyVaccine-induced intestinal immunity to ricin toxin in the absence of secretory IgA.Ricin crosses polarized human intestinal cells and intestines of ricin-gavaged mice without evident damage and then disseminates to mouse kidneysMechanistic insights into the neutralization of cytotoxic abrin by the monoclonal antibody D6F10.Passive and active vaccination strategies to prevent ricin poisoning.Immunity to ricin: fundamental insights into toxin-antibody interactions.Evidence for widespread epithelial damage and coincident production of monocyte chemotactic protein 1 in a murine model of intestinal ricin intoxicationA novel recombinant vaccine protecting mice against abrin intoxication.Discovery of high affinity anti-ricin antibodies by B cell receptor sequencing and by yeast display of combinatorial VH:VL libraries from immunized animals.Monoclonal antibodies and toxins--a perspective on function and isotype.Association of a protective monoclonal IgA with the O antigen of Salmonella enterica serovar Typhimurium impacts type 3 secretion and outer membrane integrity.Exposure of Salmonella enterica Serovar typhimurium to a protective monoclonal IgA triggers exopolysaccharide production via a diguanylate cyclase-dependent pathway.A neutralizing antibody to the a chain of abrin inhibits abrin toxicity both in vitro and in vivo.Secretory IgA: arresting microbial pathogens at epithelial borders.Absorption, distribution and pathological injury in mice due to ricin poisoning via the alimentary pathwayMulti-faceted functions of secretory IgA at mucosal surfaces.The gastrointestinal frontier: IgA and virusesThe epithelial barrier and immunoglobulin A system in allergy.Conformation-dependent high-affinity potent ricin-neutralizing monoclonal antibodies.
P2860
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P2860
Immunoglobulin A antibodies against ricin A and B subunits protect epithelial cells from ricin intoxication
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Immunoglobulin A antibodies ag ...... cells from ricin intoxication
@ast
Immunoglobulin A antibodies ag ...... cells from ricin intoxication
@en
Immunoglobulin A antibodies ag ...... cells from ricin intoxication
@nl
type
label
Immunoglobulin A antibodies ag ...... cells from ricin intoxication
@ast
Immunoglobulin A antibodies ag ...... cells from ricin intoxication
@en
Immunoglobulin A antibodies ag ...... cells from ricin intoxication
@nl
prefLabel
Immunoglobulin A antibodies ag ...... cells from ricin intoxication
@ast
Immunoglobulin A antibodies ag ...... cells from ricin intoxication
@en
Immunoglobulin A antibodies ag ...... cells from ricin intoxication
@nl
P2093
P2860
P356
P1476
Immunoglobulin A antibodies ag ...... cells from ricin intoxication
@en
P2093
Carolyn R McGuinness
Gary Edwards
Oluwakemi Sonuyi
Stephanie A Farrant
P2860
P304
P356
10.1128/IAI.02088-05
P407
P577
2006-06-01T00:00:00Z