SKP2 oncogene is a direct MYC target gene and MYC down-regulates p27(KIP1) through SKP2 in human leukemia cells.
about
Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activitySkp2: a novel potential therapeutic target for prostate cancerDysregulation of ubiquitin ligases in cancerChk1 targeting reactivates PP2A tumor suppressor activity in cancer cellsDeregulation of F-box proteins and its consequence on cancer development, progression and metastasis.A design principle underlying the paradoxical roles of E3 ubiquitin ligasesHigh p27 protein levels in chronic lymphocytic leukemia are associated to low Myc and Skp2 expression, confer resistance to apoptosis and antagonize Myc effects on cell cycleMiR-7 triggers cell cycle arrest at the G1/S transition by targeting multiple genes including Skp2 and Psme3.Bmi1 drives stem-like properties and is associated with migration, invasion, and poor prognosis in tongue squamous cell carcinoma.The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling.Prodigiosin down-regulates SKP2 to induce p27(KIP1) stabilization and antiproliferation in human lung adenocarcinoma cells.Decreased skp2 expression is necessary but not sufficient for therapy-induced senescence in prostate cancerMammalian alteration/deficiency in activation 3 (Ada3) is essential for embryonic development and cell cycle progression.Knocking-down of CREPT prohibits the progression of oral squamous cell carcinoma and suppresses cyclin D1 and c-Myc expression.Epstein-Barr virus latent membrane protein 2A enhances MYC-driven cell cycle progression in a mouse model of B lymphoma.Cellular Homeostasis and Antioxidant Response in Epithelial HT29 Cells on Titania Nanotube Arrays Surface.MYC degradationN-myc regulates growth and fiber cell differentiation in lens development.The p27-Skp2 axis mediates glucocorticoid-induced cell cycle arrest in T-lymphoma cells.MYC antagonizes the differentiation induced by imatinib in chronic myeloid leukemia cells through downregulation of p27(KIP1.).MYC Modulation around the CDK2/p27/SKP2 AxisFBXO32 Targets c-Myc for Proteasomal Degradation and Inhibits c-Myc Activity.p53, SKP2, and DKK3 as MYCN Target Genes and Their Potential Therapeutic Significance.Supraphysiologic Testosterone Therapy in the Treatment of Prostate Cancer: Models, Mechanisms and Questions.Quinacrine upregulates p21/p27 independent of p53 through autophagy-mediated downregulation of p62-Skp2 axis in ovarian cancer.Regulation and Function of the MYC Oncogene
P2860
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P2860
SKP2 oncogene is a direct MYC target gene and MYC down-regulates p27(KIP1) through SKP2 in human leukemia cells.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
SKP2 oncogene is a direct MYC target gene and MYC down-regulates p27
@nl
SKP2 oncogene is a direct MYC ...... SKP2 in human leukemia cells.
@ast
SKP2 oncogene is a direct MYC ...... SKP2 in human leukemia cells.
@en
type
label
SKP2 oncogene is a direct MYC target gene and MYC down-regulates p27
@nl
SKP2 oncogene is a direct MYC ...... SKP2 in human leukemia cells.
@ast
SKP2 oncogene is a direct MYC ...... SKP2 in human leukemia cells.
@en
prefLabel
SKP2 oncogene is a direct MYC target gene and MYC down-regulates p27
@nl
SKP2 oncogene is a direct MYC ...... SKP2 in human leukemia cells.
@ast
SKP2 oncogene is a direct MYC ...... SKP2 in human leukemia cells.
@en
P2093
P2860
P50
P356
P1476
SKP2 oncogene is a direct MYC ...... h SKP2 in human leukemia cells
@en
P2093
Gabriel Bretones
Juan M Caraballo
M Pilar Albero
Marta Albajar
Paula Ruiz
Rosa Blanco
Wen-Chun Hung
P2860
P304
P356
10.1074/JBC.M110.165977
P407
P577
2011-01-18T00:00:00Z