The histone deacetylase inhibitor, vorinostat, reduces tumor growth at the metastatic bone site and associated osteolysis, but promotes normal bone loss
about
Prediction of cancer drugs by chemical-chemical interactionsHistone deacetylase 3 supports endochondral bone formation by controlling cytokine signaling and matrix remodeling.Cancer Epigenetics: Mechanisms and Crosstalk of a HDAC Inhibitor, VorinostatHistone deacetylase inhibition destabilizes the multi-potent state of uncommitted adipose-derived mesenchymal stromal cellsPreclinical evaluation of sunitinib as a single agent in the prophylactic setting in a mouse model of bone metastasesSuberoylanilide hydroxamic acid (SAHA; vorinostat) causes bone loss by inhibiting immature osteoblasts.Hdac-mediated control of endochondral and intramembranous ossificationHistone Deacetylases in Bone Development and Skeletal Disorders.Histone deacetylase 3 is required for maintenance of bone mass during agingUnderstanding and targeting osteoclastic activity in prostate cancer bone metastases.Various ways to improve whole cancer cell vaccines.Chromatin modifiers and histone modifications in bone formation, regeneration, and therapeutic intervention for bone-related disease.Integrin αvβ6 promotes an osteolytic program in cancer cells by upregulating MMP2.NCL1, a highly selective lysine-specific demethylase 1 inhibitor, suppresses prostate cancer without adverse effect.Profiling of human epigenetic regulators using a semi-automated real-time qPCR platform validated by next generation sequencing.Effect of the HDAC inhibitor vorinostat on the osteogenic differentiation of mesenchymal stem cells in vitro and bone formation in vivo.Histone deacetylase 3 suppresses Erk phosphorylation and matrix metalloproteinase (Mmp)-13 activity in chondrocytes.Addition of a histone deacetylase inhibitor increases recombinant protein expression in Medicago truncatula cell cultures.Hallmarks of Bone Metastasis.Synergistic Immunostimulatory Effects and Therapeutic Benefit of Combined Histone Deacetylase and Bromodomain Inhibition in Non-Small Cell Lung Cancer.Mesenchymal stem cells in multiple myeloma: a therapeutical tool or target?
P2860
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P2860
The histone deacetylase inhibitor, vorinostat, reduces tumor growth at the metastatic bone site and associated osteolysis, but promotes normal bone loss
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
The histone deacetylase inhibi ...... but promotes normal bone loss
@ast
The histone deacetylase inhibi ...... but promotes normal bone loss
@en
The histone deacetylase inhibi ...... but promotes normal bone loss
@nl
type
label
The histone deacetylase inhibi ...... but promotes normal bone loss
@ast
The histone deacetylase inhibi ...... but promotes normal bone loss
@en
The histone deacetylase inhibi ...... but promotes normal bone loss
@nl
prefLabel
The histone deacetylase inhibi ...... but promotes normal bone loss
@ast
The histone deacetylase inhibi ...... but promotes normal bone loss
@en
The histone deacetylase inhibi ...... but promotes normal bone loss
@nl
P2093
P2860
P1476
The histone deacetylase inhibi ...... but promotes normal bone loss
@en
P2093
Andre J van Wijnen
Gabriela Szabo
Gary S Stein
Jacqueline Akech
Jane B Lian
Janet L Stein
Jennifer J Westendorf
Jitesh Pratap
John J Wixted
Krystin Bedard
P2860
P304
P356
10.1158/1535-7163.MCT-10-0572
P577
2010-12-01T00:00:00Z