Synthetic studies on the bryostatins: synthetic routes to analogues containing the tricyclic macrolactone core
about
Molecular modeling, total synthesis, and biological evaluations of C9-deoxy bryostatin 1Total synthesis of bryostatin 7 via C-C bond-forming hydrogenationEfficient synthetic access to a new family of highly potent bryostatin analogues via a Prins-driven macrocyclization strategy.Synthesis of a des-B-ring bryostatin analogue leads to an unexpected ring expansion of the bryolactone coreTranslating Nature's Library: The Bryostatins and Function-Oriented SynthesisTotal synthesis of bryostatin 1Convergent assembly of highly potent analogues of bryostatin 1 via pyran annulation: bryostatin look-alikes that mimic phorbol ester function.Synthetic studies on the bryostatins: preparation of a truncated BC-ring intermediate by pyran annulation.Synthetic Studies Toward Bryostatin 1: Preparation of a C(1)-C(16) Fragment by Pyran AnnulationMechanistic and computational studies of exocyclic stereocontrol in the synthesis of bryostatin-like cis-2,6-disubstituted 4-alkylidenetetrahydropyrans by Prins cyclization.Total synthesis of leucascandrolide a: a new application of the Mukaiyama aldol-Prins reactionSynthetic studies toward the bryostatins: a substrate-controlled approach to the A-ringThe medicinal potential of promising marine macrolides with anticancer activity.Role of the C8 gem-dimethyl group of bryostatin 1 on its unique pattern of biological activity.1,n-glycols as dialdehyde equivalents in iridium-catalyzed enantioselective carbonyl allylation and iterative two-directional assembly of 1,3-polyols.Synthesis of a ring-expanded bryostatin analogue.A new construction of 2-alkoxypyrans by an acylation-reductive cyclization sequence.Concise synthesis of the bryostatin A-ring via consecutive C-C bond forming transfer hydrogenations.Substitution on the A-ring confers to bryopyran analogues the unique biological activity characteristic of bryostatins and distinct from that of the phorbol esters.Synthetically amenable amide derivatives of tosylated-amino acids as organocatalysts for enantioselective allylation of aldehydes: computational rationale for enantioselectivity.
P2860
Q24599839-3A33558D-59B9-4EA6-B182-C917938BFE53Q24607710-9A6EC9DB-BA94-4FD5-B1A3-1CB9B1BD4D77Q33331435-9F430E2C-7279-4500-89E1-9FC1D7280A72Q34282624-6E425CBC-CBDE-443E-8C9C-0EC2A1056921Q34290699-4622720D-B602-4C91-AEFE-72DF3FE53F8BQ34538229-B9EB8639-2636-4CAE-A98C-9EBAE6DBEEB6Q34591418-896562C2-8932-49C7-BF92-727727FBA3FBQ34686860-E50022BB-512B-4FA3-A017-176171474C84Q35741019-3F44D29C-0BEF-48D2-A718-52E7F84B4C25Q36510954-5DA6329E-E09A-4F35-8E6F-15266CA24764Q36824422-694A71A8-2C22-4F76-BFE9-E2B4C52D8F3BQ36837850-9DD688BE-1D4E-4B6B-B0B1-3EB06B046995Q37837738-CA298858-1A60-44A0-9ED6-08DF6A8ECF4BQ39349800-9064DD25-753D-4FE7-8114-49F38E3BCBEFQ39752033-118A81CD-4FD6-4F28-B82B-FD00566E6A2CQ40174456-4EE2CD64-A10C-43D4-8403-95C00C075474Q42141736-A6DF5DBD-4AB4-43A8-B052-DF1C958531CFQ43068920-B50F4F16-3555-4EF6-9A3B-52B923E7D68EQ43174247-2F4FF682-933E-40D3-A784-3464BA6939E7Q45839654-4F55B5E1-63F5-473B-A526-640CD2C718AE
P2860
Synthetic studies on the bryostatins: synthetic routes to analogues containing the tricyclic macrolactone core
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Synthetic studies on the bryos ...... he tricyclic macrolactone core
@ast
Synthetic studies on the bryos ...... he tricyclic macrolactone core
@en
Synthetic studies on the bryos ...... he tricyclic macrolactone core
@nl
type
label
Synthetic studies on the bryos ...... he tricyclic macrolactone core
@ast
Synthetic studies on the bryos ...... he tricyclic macrolactone core
@en
Synthetic studies on the bryos ...... he tricyclic macrolactone core
@nl
prefLabel
Synthetic studies on the bryos ...... he tricyclic macrolactone core
@ast
Synthetic studies on the bryos ...... he tricyclic macrolactone core
@en
Synthetic studies on the bryos ...... he tricyclic macrolactone core
@nl
P2860
P356
P1433
P1476
Synthetic studies on the bryos ...... he tricyclic macrolactone core
@en
P2093
Anh P Truong
Gary E Keck
P2860
P304
P356
10.1021/OL050512O
P407
P577
2005-05-01T00:00:00Z