Spontaneous dormancy of metastatic breast cancer cells in an all human liver microphysiologic system
about
Targeting dormant micrometastases: rationale, evidence to date and clinical implicationsA recapitulative three-dimensional model of breast carcinoma requires perfusion for multi-week growthBiology-inspired microphysiological system approaches to solve the prediction dilemma of substance testingIntegrated Assessment of Diclofenac Biotransformation, Pharmacokinetics, and Omics-Based Toxicity in a Three-Dimensional Human Liver-Immunocompetent Coculture System.Lung epithelial cells induce both phenotype alteration and senescence in breast cancer cells.Patients with hepatic breast cancer metastases demonstrate highly specific profiles of matrix metalloproteinases MMP-2 and MMP-9 after SIRT treatment as compared to other primary and secondary liver tumours.The Predictive Link between Matrix and Metastasis.Macrophage phenotypic subtypes diametrically regulate epithelial-mesenchymal plasticity in breast cancer cells.Quantitative Assessment of Population Variability in Hepatic Drug Metabolism Using a Perfused Three-Dimensional Human Liver Microphysiological System.Tissue chips - innovative tools for drug development and disease modeling.Integrated gut/liver microphysiological systems elucidates inflammatory inter-tissue crosstalk.Liver metastases: Microenvironments and ex-vivo models.A Pathway to Personalizing Therapy for Metastases Using Liver-on-a-Chip Platforms.Biomimetic strategies to recapitulate organ specific microenvironments for studying breast cancer metastasis.Opportunities and challenges in the wider adoption of liver and interconnected microphysiological systems.Modeling Therapeutic Antibody-Small Molecule Drug-Drug Interactions Using a Three-Dimensional Perfusable Human Liver Coculture Platform.Liver-Tumor Hybrid Organoids for Modeling Tumor Growth and Drug Response In Vitro.Bi-directional exosome-driven intercommunication between the hepatic niche and cancer cells.Liver 'organ on a chip'.A model of dormant-emergent metastatic breast cancer progression enabling exploration of biomarker signatures.Tumor Associated Macrophages as Therapeutic Targets for Breast Cancer.Inflammatory cytokine IL-8/CXCL8 promotes tumour escape from hepatocyte-induced dormancy.A liver microphysiological system of tumor cell dormancy and inflammatory responsiveness is affected by scaffold properties.Interconnected Microphysiological Systems for Quantitative Biology and Pharmacology Studies.Lipophilic statins limit cancer cell growth and survival, via involvement of Akt signaling.
P2860
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P2860
Spontaneous dormancy of metastatic breast cancer cells in an all human liver microphysiologic system
description
2014 nî lūn-bûn
@nan
2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Spontaneous dormancy of metast ...... liver microphysiologic system
@ast
Spontaneous dormancy of metast ...... liver microphysiologic system
@en
Spontaneous dormancy of metast ...... liver microphysiologic system
@nl
type
label
Spontaneous dormancy of metast ...... liver microphysiologic system
@ast
Spontaneous dormancy of metast ...... liver microphysiologic system
@en
Spontaneous dormancy of metast ...... liver microphysiologic system
@nl
prefLabel
Spontaneous dormancy of metast ...... liver microphysiologic system
@ast
Spontaneous dormancy of metast ...... liver microphysiologic system
@en
Spontaneous dormancy of metast ...... liver microphysiologic system
@nl
P2093
P2860
P50
P356
P1476
Spontaneous dormancy of metast ...... liver microphysiologic system
@en
P2093
D Lauffenburger
D P Taylor
L Griffith
R Venkataramanan
V C Pillai
P2860
P2888
P304
P356
10.1038/BJC.2014.533
P407
P577
2014-10-14T00:00:00Z
P6179
1048415028