Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene.
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Messing up disorder: how do missense mutations in the tumor suppressor protein APC lead to cancer?Large extent of disorder in Adenomatous Polyposis Coli offers a strategy to guard Wnt signalling against point mutationsBinding of APC and dishevelled mediates Wnt5a-regulated focal adhesion dynamics in migrating cellsActivator protein 2alpha suppresses intestinal tumorigenesis in the Apc(min) mouseTargeting and transport: how microtubules control focal adhesion dynamicsAberrant DNA methylation in cervical carcinogenesisDifferential regulation of microtubule severing by APC underlies distinct patterns of projection neuron and interneuron migration.8p22 MTUS1 gene product ATIP3 is a novel anti-mitotic protein underexpressed in invasive breast carcinoma of poor prognosisMolecular Basis for the Recognition of Adenomatous Polyposis Coli by the Discs Large 1 ProteinStructural and functional insights into the regulation mechanism of CK2 by IP6 and the intrinsically disordered protein Nopp140Racial disparity in colorectal cancer: Gut microbiome and cancer stem cellsWnt-signalling pathways and microRNAs network in carcinogenesis: experimental and bioinformatics approachesNew functions for alpha-catenins in health and disease: from cancer to heart regenerationMitogen-activated protein kinase (MAPK/ERK) regulates adenomatous polyposis coli during growth-factor-induced cell extensionCanonical correlation analysis for RNA-seq co-expression networksPotential implication of the chemical properties and bioactivity of nitrone spin traps for therapeuticsStructural basis for the recognition of Asef by adenomatous polyposis coli.The intrinsic disorder alphabet. III. Dual personality of serine.Cyclin A/cdk2 regulates adenomatous polyposis coli-dependent mitotic spindle anchoring.The adenomatous polyposis coli protein is an essential regulator of radial glial polarity and construction of the cerebral cortex.An NGS Workflow Blueprint for DNA Sequencing Data and Its Application in Individualized Molecular Oncology.Anti-oncogenic and pro-differentiation effects of clorgyline, a monoamine oxidase A inhibitor, on high grade prostate cancer cells.Anti-cancer activity of nitrones in the Apc(Min/+) model of colorectal cancerTopoisomerase IIalpha binding domains of adenomatous polyposis coli influence cell cycle progression and aneuploidy.Smad4-mediated TGF-beta signaling in tumorigenesis.Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis.Tumor inhibition by sodium selenite is associated with activation of c-Jun NH2-terminal kinase 1 and suppression of beta-catenin signaling.Stromal deletion of the APC tumor suppressor in mice triggers development of endometrial cancerChanges in gene expression and cellular architecture in an ovarian cancer progression model.Blood-testis barrier and spermatogenesis: lessons from genetically-modified mice.Readthrough of premature termination codons in the adenomatous polyposis coli gene restores its biological activity in human cancer cellsAdenomatous polyposis coli regulates axon arborization and cytoskeleton organization via its N-terminus.Cell type-specific expression of adenomatous polyposis coli in lung development, injury, and repair.Integrated transcriptome and binding sites analysis implicates E2F in the regulation of self-renewal in human pluripotent stem cells.Protein mislocalization: mechanisms, functions and clinical applications in cancer.MicroRNAs: key players of taxane resistance and their therapeutic potential in human cancers.The tumor suppressor adenomatous polyposis coli controls the direction in which a cell extrudes from an epitheliumWnt-related molecules and signaling pathway equilibrium in hematopoiesis.Complete deletion of Apc results in severe polyposis in mice.Lynch syndrome: an updated review
P2860
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P2860
Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene.
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene.
@ast
Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene.
@en
type
label
Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene.
@ast
Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene.
@en
prefLabel
Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene.
@ast
Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene.
@en
P356
P1476
Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene.
@en
P2093
Makoto M Taketo
P304
P356
10.1242/JCS.03485
P407
P577
2007-10-01T00:00:00Z