Dendritic cells and hepatocytes use distinct pathways to process protective antigen from plasmodium in vivo - Wikidata - wikimedia - TriplyDB

Dendritic cells and hepatocytes use distinct pathways to process protective antigen from plasmodium in vivo

Dendritic cells and hepatocytes use distinct pathways to process protective antigen from plasmodium in vivo

http://www.wikidata.org/entity/Q34693251

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Immune mechanisms in malaria: new insights in vaccine development The Use of Synthetic Carriers in Malaria Vaccine Design Tissue signatures influence the activation of intrahepatic CD8(+) T cells against malaria sporozoites Lymph-node resident CD8α+ dendritic cells capture antigens from migratory malaria sporozoites and induce CD8+ T cell responses The Plasmodium translocon of exported proteins (PTEX) component thioredoxin-2 is important for maintaining normal blood-stage growth Protective immunity to liver-stage malaria Plasmodium cellular effector mechanisms and the hepatic microenvironment Liver-specific protein 2: a Plasmodium protein exported to the hepatocyte cytoplasm and required for merozoite formation CD8+ T cells specific for a malaria cytoplasmic antigen form clusters around infected hepatocytes and are protective at the liver stage of infection.Engineering of Genetically Arrested Parasites (GAPs) For a Precision Malaria Vaccine Malaria immunity in man and mosquito: insights into unsolved mysteries of a deadly infectious disease.Antigen export during liver infection of the malaria parasite augments protective immunity The chemokine receptor CXCR6 is required for the maintenance of liver memory CD8⁺ T cells specific for infectious pathogens.A nonintegrative lentiviral vector-based vaccine provides long-term sterile protection against malaria CSP--a model for in vivo presentation of Plasmodium berghei sporozoite antigens by hepatocytes Dynamics of the major histocompatibility complex class I processing and presentation pathway in the course of malaria parasite development in human hepatocytes: implications for vaccine development.Antigen-driven focal inflammatory death of malaria liver stages Malaria and the liver: immunological hide-and-seek or subversion of immunity from within?Requirement of UNC93B1 reveals a critical role for TLR7 in host resistance to primary infection with Trypanosoma cruzi.Studying the effect of chloroquine on sporozoite-induced protection and immune responses in Plasmodium berghei malaria P. falciparum and P. vivax Epitope-Focused VLPs Elicit Sterile Immunity to Blood Stage Infections.Proteolytic Cleavage of the Plasmodium falciparum Circumsporozoite Protein Is a Target of Protective Antibodies.Protective antibody and CD8+ T-cell responses to the Plasmodium falciparum circumsporozoite protein induced by a nanoparticle vaccine Memory CD8 T cells specific for plasmodia liver-stage antigens maintain protracted protection against malaria.Skin-draining lymph node priming is sufficient to induce sterile immunity against pre-erythrocytic malaria.UNC93B1 and nucleic acid-sensing Toll-like receptors mediate host resistance to infection with Leishmania major Discriminating Protective from Nonprotective Plasmodium-Specific CD8+ T Cell Responses Development of a chimeric Plasmodium berghei strain expressing the repeat region of the P. vivax circumsporozoite protein for in vivo evaluation of vaccine efficacy.Unique transcriptional profile of liver-resident memory CD8+ T cells induced by immunization with malaria sporozoites Systemic toll-like receptor ligation and selective killing of dendritic cell subsets fail to dissect priming pathways for anti-vaccinia virus CD8⁺ T cells Angiotensin II type-1 receptor (AT1R) regulates expansion, differentiation, and functional capacity of antigen-specific CD8(+) T cells.Malaria parasite pre-erythrocytic infection: preparation meets opportunity.The Threshold of Protection from Liver-Stage Malaria Relies on a Fine Balance between the Number of Infected Hepatocytes and Effector CD8+ T Cells Present in the Liver CD8+ T cells eliminate liver-stage Plasmodium berghei parasites without detectable bystander effect.Induction and maintenance of protective CD8+ T cells against malaria liver stages: implications for vaccine development.Dendritic cells and the malaria pre-erythrocytic stage.The skin: where malaria infection and the host immune response begin Feeling at home from arrival to departure: protein export and host cell remodelling during Plasmodium liver stage and gametocyte maturation.Do you see what I see: Recognition of protozoan parasites by Toll-like receptors.From the draining lymph node to the liver: the induction and effector mechanisms of malaria-specific CD8+ T cells.

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Dendritic cells and hepatocytes use distinct pathways to process protective antigen from plasmodium in vivo

http://www.wikidata.org/entity/Q34693251

description

2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Dendritic cells and hepatocyte ...... ntigen from plasmodium in vivo

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Dendritic cells and hepatocyte ...... ntigen from plasmodium in vivo

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Dendritic cells and hepatocyte ...... ntigen from plasmodium in vivo

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type

label

Dendritic cells and hepatocyte ...... ntigen from plasmodium in vivo

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Dendritic cells and hepatocyte ...... ntigen from plasmodium in vivo

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Dendritic cells and hepatocyte ...... ntigen from plasmodium in vivo

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prefLabel

Dendritic cells and hepatocyte ...... ntigen from plasmodium in vivo

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Dendritic cells and hepatocyte ...... ntigen from plasmodium in vivo

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Dendritic cells and hepatocyte ...... ntigen from plasmodium in vivo

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JOURNAL.PPAT.1001318

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Dendritic cells and hepatocyte ...... ntigen from plasmodium in vivo

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Andrea J Radtke

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Fidel Zavala

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Photini Sinnis

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Prakash Srinivasan

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Sze-Wah Tse

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Yun-Chi Chen

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P2860

Selective suicide of cross-presenting CD8+ dendritic cells by cytochrome c injection shows functional heterogeneity within this subset

Exit of Plasmodium sporozoites from oocysts is an active process that involves the circumsporozoite protein.

UNC93B1 mediates host resistance to infection with Toxoplasma gondii

Prolonged antigen presentation is required for optimal CD8+ T cell responses against malaria liver stage parasites

Dynamic imaging of experimental Leishmania donovani-induced hepatic granulomas detects Kupffer cell-restricted antigen presentation to antigen-specific CD8 T cells

Protective immunity produced by the injection of x-irradiated sporozoites of plasmodium berghei

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9

TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells

In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens

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e1001318

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10.1371/JOURNAL.PPAT.1001318

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3

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7

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50892300

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21445239

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3060173

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