Branch-point attack in group II introns is a highly reversible transesterification, providing a potential proofreading mechanism for 5'-splice site selection.
about
Control of branch-site choice by a group II intronSynthetic lethality of yeast slt mutations with U2 small nuclear RNA mutations suggests functional interactions between U2 and U5 snRNPs that are important for both steps of pre-mRNA splicing.Upf1p control of nonsense mRNA translation is regulated by Nmd2p and Upf3pCleavage mediated by the P15 domain of bacterial RNase P RNAA manganese-dependent ribozyme in the 3'-untranslated region of Xenopus Vg1 mRNADiversity, mobility, and structural and functional evolution of group II introns carrying an unusual 3' extension.Deletion of a conserved dinucleotide inhibits the second step of group II intron splicing.Nonsense-containing mRNAs that accumulate in the absence of a functional nonsense-mediated mRNA decay pathway are destabilized rapidly upon its restitutionQuantification of pre-mRNA escape rate and synergy in splicing.Group II introns: mobile ribozymes that invade DNA.Mobile Bacterial Group II Introns at the Crux of Eukaryotic EvolutionThe tertiary structure of group II introns: implications for biological function and evolutionThree essential and conserved regions of the group II intron are proximal to the 5'-splice site.Tight binding of the 5' exon to domain I of a group II self-splicing intron requires completion of the intron active siteThe two steps of group II intron self-splicing are mechanistically distinguishable.Activating the branch-forming splicing pathway by reengineering the ribozyme component of a natural group II intron.A conserved element that stabilizes the group II intron active site.Visualizing the solvent-inaccessible core of a group II intron ribozymeLinking the group II intron catalytic domains: tertiary contacts and structural features of domain 3.Length changes in the joining segment between domains 5 and 6 of a group II intron inhibit self-splicing and alter 3' splice site selection.A three-dimensional perspective on exon binding by a group II self-splicing intron.An RNA conformational change between the two chemical steps of group II self-splicing.Defining functional groups, core structural features and inter-domain tertiary contacts essential for group II intron self-splicing: a NAIM analysis.RNA catalysis as a probe for chaperone activity of DEAD-box helicases.Influence of substrate structure on in vitro ribozyme activity of a group II intron.Relevance of the branch point adenosine, coordination loop, and 3' exon binding site for in vivo excision of the Sinorhizobium meliloti group II intron RmInt1.Extensive mis-splicing of a bi-partite plant mitochondrial group II intron.Hammerhead ribozyme kinetics.
P2860
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P2860
Branch-point attack in group II introns is a highly reversible transesterification, providing a potential proofreading mechanism for 5'-splice site selection.
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
name
Branch-point attack in group I ...... for 5'-splice site selection.
@ast
Branch-point attack in group I ...... for 5'-splice site selection.
@en
Branch-point attack in group I ...... for 5'-splice site selection.
@nl
type
label
Branch-point attack in group I ...... for 5'-splice site selection.
@ast
Branch-point attack in group I ...... for 5'-splice site selection.
@en
Branch-point attack in group I ...... for 5'-splice site selection.
@nl
prefLabel
Branch-point attack in group I ...... for 5'-splice site selection.
@ast
Branch-point attack in group I ...... for 5'-splice site selection.
@en
Branch-point attack in group I ...... for 5'-splice site selection.
@nl
P2860
P1433
P1476
Branch-point attack in group I ...... m for 5'-splice site selection
@en
P2860
P304
P407
P577
1995-06-01T00:00:00Z