Common genetic variation in the human FNDC5 locus, encoding the novel muscle-derived 'browning' factor irisin, determines insulin sensitivity
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Impact of exercise on muscle and nonmuscle organsIdentification of Four Mouse Diabetes Candidate Genes Altering β-Cell ProliferationExercise and diabetes: relevance and causes for response variabilitySerum Irisin and Oxytocin Levels as Predictors of Metabolic Parameters in Obese Children.Loss-of-function myostatin mutation increases insulin sensitivity and browning of white fat in Meishan pigs.An interaction between a FNDC5 variant and obesity modulates glucose metabolism in a Chinese Han population.FNDC5 (irisin) gene and exceptional longevity: a functional replication study with rs16835198 and rs726344 SNPs.SNPs in FNDC5 (irisin) are associated with obesity and modulation of glucose and lipid metabolism in Saudi subjects.ROCK1 reduces mitochondrial content and irisin production in muscle suppressing adipocyte browning and impairing insulin sensitivity.FNDC5 expression and circulating irisin levels are modified by diet and hormonal conditions in hypothalamus, adipose tissue and muscle.Irisin, two years laterEffects of Body Weight Reduction on Serum Irisin and Metabolic Parameters in Obese SubjectsAssociation of metabolic parameters and rs726344 in FNDC5 with serum irisin concentrations.Irisin in idiopathic foetal growth restriction.Epistasis, physical capacity-related genes and exceptional longevity: FNDC5 gene interactions with candidate genes FOXOA3 and APOE.A prospective evaluation of clinical and genetic predictors of weight changes in breast cancer survivors.Effects of Irisin and Exercise on Metabolic Parameters and Reproductive Hormone Levels in High-Fat Diet-Induced Obese Female Mice.High circulating irisin levels are associated with insulin resistance and vascular atherosclerosis in a cohort of nondiabetic adult subjects.Effects of obesity, diabetes and exercise on Fndc5 gene expression and irisin release in human skeletal muscle and adipose tissue: in vivo and in vitro studies.Identification of proliferative and mature β-cells in the islets of Langerhans.Circulating irisin is associated with osteoporotic fractures in postmenopausal women with low bone mass but is not affected by either teriparatide or denosumab treatment for 3 months.
P2860
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P2860
Common genetic variation in the human FNDC5 locus, encoding the novel muscle-derived 'browning' factor irisin, determines insulin sensitivity
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2013 nî lūn-bûn
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2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի ապրիլին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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Common genetic variation in th ...... determines insulin sensitivity
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Common genetic variation in th ...... determines insulin sensitivity
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Common genetic variation in th ...... determines insulin sensitivity
@nl
type
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Common genetic variation in th ...... determines insulin sensitivity
@ast
Common genetic variation in th ...... determines insulin sensitivity
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Common genetic variation in th ...... determines insulin sensitivity
@nl
prefLabel
Common genetic variation in th ...... determines insulin sensitivity
@ast
Common genetic variation in th ...... determines insulin sensitivity
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Common genetic variation in th ...... determines insulin sensitivity
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P2093
P2860
P50
P1433
P1476
Common genetic variation in th ...... determines insulin sensitivity
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P2093
Andreas Fritsche
Cora Weigert
Fausto Machicao
Fritz Schick
Jürgen Machann
Lucia Berti
Mika Scheler
P2860
P304
P356
10.1371/JOURNAL.PONE.0061903
P407
P577
2013-04-25T00:00:00Z