Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's disease - Wikidata - wikimedia - TriplyDB

Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's disease

Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's disease

http://www.wikidata.org/entity/Q34708307

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The hypocretin/orexin system in sleep disorders: preclinical insights and clinical progress Candidate mechanisms underlying the association between sleep-wake disruptions and Alzheimer's disease Chronic sleep disturbance and neural injury: links to neurodegenerative disease Orexin signaling regulates both the hippocampal clock and the circadian oscillation of Alzheimer's disease-risk genes Metabolic and Non-Cognitive Manifestations of Alzheimer's Disease: The Hypothalamus as Both Culprit and Target of Pathology Locus Coeruleus, norepinephrine and Aβ peptides in Alzheimer's disease How amyloid, sleep and memory connect.Orexin-A is Associated with Increases in Cerebrospinal Fluid Phosphorylated-Tau in Cognitively Normal Elderly Subjects.Perspectives on the Tertiary Prevention Strategy for Alzheimer's Disease.A proposed preventive role for Gamma-hydroxybutyrate (Xyrem(R)) in Alzheimer's disease.Altered sleep and EEG power in the P301S Tau transgenic mouse model.Tetraspanin 6: a pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments."Boomerang Neuropathology" of Late-Onset Alzheimer's Disease is Shrouded in Harmful "BDDS": Breathing, Diet, Drinking, and Sleep During Aging.Cerebrospinal Fluid Aβ42 Levels: When Physiological Become Pathological State.Metabolite Clearance During Wakefulness and Sleep.Sleep: A Novel Mechanistic Pathway, Biomarker, and Treatment Target in the Pathology of Alzheimer's Disease?Mitochondria, Cybrids, Aging, and Alzheimer's Disease.Mechanisms linking circadian clocks, sleep, and neurodegeneration.Orexin OX2 Receptor Antagonists as Sleep Aids.Self-Reported Sleep Apnea and Dementia Risk: Findings from the Prevention of Alzheimer's Disease with Vitamin E and Selenium Trial.The Glymphatic Pathway.Is suvorexant a better choice than alternative hypnotics?Neurodegeneration: paying it off with sleep.From radioimmunoassay to mass spectrometry: a new method to quantify orexin-A (hypocretin-1) in cerebrospinal fluid.Sleeping our Alzheimer's risk away.Excessive Sleepiness and Longer Nighttime in Bed Increase the Risk of Cognitive Decline in Frail Elderly Subjects: The MAPT-Sleep Study Neuropsychiatric signs and symptoms of Alzheimer's disease: New treatment paradigms.Enhanced sleep reverses memory deficits and underlying pathology in Drosophila models of Alzheimer's disease.Slow wave sleep disruption increases cerebrospinal fluid amyloid-β levels.Brain rhythm attractor breakdown in Alzheimer's disease: Functional and pathologic implications.Central and peripheral circadian clocks and their role in Alzheimer's disease.Anesthesia with Dexmedetomidine and Low-dose Isoflurane Increases Solute Transport via the Glymphatic Pathway in Rat Brain When Compared with High-dose Isoflurane.Orexin Impairs the Phagocytosis and Degradation of Amyloid-β Fibrils by Microglial Cells.Orexin and Alzheimer's Disease.Regulation of amyloid-β dynamics and pathology by the circadian clock.Interactions between stress and physical activity on Alzheimer's disease pathology.The Orexin/Receptor System: Molecular Mechanism and Therapeutic Potential for Neurological Diseases.Orexin Receptor Antagonists

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Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's disease

http://www.wikidata.org/entity/Q34708307

description

2014 nî lūn-bûn

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2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2014 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年學術文章

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name

Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's disease

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Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's disease

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Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's disease

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Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's disease

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Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's disease

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Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's disease

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Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's disease

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Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's disease

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Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's disease

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Journal of Experimental Medicine

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Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's disease

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P2093

Ashish Heda

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B Joy Snider

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David M Holtzman

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Floy R Stewart

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Hong Jiang

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Jee Hoon Roh

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John R Cirrito

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Mary Beth Finn

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Masashi Yanagisawa

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Mingjie Li

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P2860

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

A default mode of brain function

Tuning arousal with optogenetic modulation of locus coeruleus neurons.

Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

Local sleep in awake rats.

Spatial correlation between brain aerobic glycolysis and amyloid-β (Aβ ) deposition

Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle

Cortical firing and sleep homeostasis

Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

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2487-2496

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scholarly article

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10.1084/JEM.20141788

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13

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211

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Thomas E. Mahan

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2014-11-24T00:00:00Z

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268874706

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25422493

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Alzheimer's disease

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4267230

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