Stress-induced enzyme activation primes murine embryonic stem cells to differentiate toward the first extraembryonic lineage
about
Hypoxic stress induces, but cannot sustain trophoblast stem cell differentiation to labyrinthine placenta due to mitochondrial insufficiency.Hypoxic Stress Forces Irreversible Differentiation of a Majority of Mouse Trophoblast Stem Cells Despite FGF4.Development and Validation of a Rex1-RFP Potency Activity Reporter Assay That Quantifies Stress-Forced Potency Loss in Mouse Embryonic Stem Cells.Commonly used fertility drugs, a diet supplement, and stress force AMPK-dependent block of stemness and development in cultured mammalian embryos.Blastocyst-Derived Stem Cell Populations under Stress: Impact of Nutrition and Metabolism on Stem Cell Potency Loss and Miscarriage.Using stem cell oxygen physiology to optimize blastocyst culture while minimizing hypoxic stress.Two-cell embryos are more sensitive than blastocysts to AMPK-dependent suppression of anabolism and stemness by commonly used fertility drugs, a diet supplement, and stress.CoQ10 increases mitochondrial mass and polarization, ATP and Oct4 potency levels, and bovine oocyte MII during IVM while decreasing AMPK activity and oocyte death.Why AMPK agonists not known to be stressors may surprisingly contribute to miscarriage or hinder IVF/ART.
P2860
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P2860
Stress-induced enzyme activation primes murine embryonic stem cells to differentiate toward the first extraembryonic lineage
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Stress-induced enzyme activati ...... e first extraembryonic lineage
@ast
Stress-induced enzyme activati ...... e first extraembryonic lineage
@en
Stress-induced enzyme activati ...... e first extraembryonic lineage
@nl
type
label
Stress-induced enzyme activati ...... e first extraembryonic lineage
@ast
Stress-induced enzyme activati ...... e first extraembryonic lineage
@en
Stress-induced enzyme activati ...... e first extraembryonic lineage
@nl
prefLabel
Stress-induced enzyme activati ...... e first extraembryonic lineage
@ast
Stress-induced enzyme activati ...... e first extraembryonic lineage
@en
Stress-induced enzyme activati ...... e first extraembryonic lineage
@nl
P2093
P2860
P356
P1476
Stress-induced enzyme activati ...... e first extraembryonic lineage
@en
P2093
Daniel A Rappolee
Elizabeth Ella Puscheck
Jill A Slater
Sichang Zhou
P2860
P304
P356
10.1089/SCD.2014.0157
P577
2014-12-01T00:00:00Z