Shiga toxin 1 triggers a ribotoxic stress response leading to p38 and JNK activation and induction of apoptosis in intestinal epithelial cells
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Shiga toxin 2 targets the murine renal collecting duct epitheliumShiga Toxins as Multi-Functional Proteins: Induction of Host Cellular Stress Responses, Role in Pathogenesis and Therapeutic ApplicationsShiga toxin interaction with human intestinal epitheliumAdvances in pathogenesis and therapy of hemolytic uremic syndrome caused by Shiga toxin-2Mucosal injuries due to ribosome-inactivating stress and the compensatory responses of the intestinal epithelial barrierActivation of cell stress response pathways by Shiga toxinsCommensal Akkermansia muciniphila exacerbates gut inflammation in Salmonella Typhimurium-infected gnotobiotic miceIdentification of small molecules that suppress ricin-induced stress-activated signaling pathwaysDiversity and impact of prokaryotic toxins on aquatic environments: a reviewRicin A-chain requires c-Jun N-terminal kinase to induce apoptosis in nontransformed epithelial cells.Shiga toxin 2 causes apoptosis in human brain microvascular endothelial cells via C/EBP homologous protein.p38 mitogen-activated protein kinase mediates lipopolysaccharide and tumor necrosis factor alpha induction of shiga toxin 2 sensitivity in human umbilical vein endothelial cellsA new family of potent AB(5) cytotoxins produced by Shiga toxigenic Escherichia coli.Administration of ricin induces a severe inflammatory response via nonredundant stimulation of ERK, JNK, and P38 MAPK and provides a mouse model of hemolytic uremic syndrome.Contribution of polyunsaturated fatty acids to Shiga toxin cytotoxicity in human renal tubular epithelium-derived cells.Mouse model of hemolytic-uremic syndrome caused by endotoxin-free Shiga toxin 2 (Stx2) and protection from lethal outcome by anti-Stx2 antibody.Distinct physiologic and inflammatory responses elicited in baboons after challenge with Shiga toxin type 1 or 2 from enterohemorrhagic Escherichia coliEndothelial damage induced by Shiga toxins delivered by neutrophils during transmigration.Rescue from lethal Shiga toxin 2-induced renal failure with a cell-permeable peptide.Shiga toxins and the pathophysiology of hemolytic uremic syndrome in humans and animals.Activation of the Classical Mitogen-Activated Protein Kinases Is Part of the Shiga Toxin-Induced Ribotoxic Stress Response and May Contribute to Shiga Toxin-Induced Inflammation.EspP, an Extracellular Serine Protease from Enterohemorrhagic E. coli, Reduces Coagulation Factor Activities, Reduces Clot Strength, and Promotes Clot LysisInduction of apoptosis by Shiga toxins.The MAP kinase-activated protein kinase 2 (MK2) contributes to the Shiga toxin-induced inflammatory responseEffect of shiga toxin and its subunits on cytokine induction in different cell lines.Shiga toxin 1 induces apoptosis in the human myelogenous leukemia cell line THP-1 by a caspase-8-dependent, tumor necrosis factor receptor-independent mechanism.Shiga toxin 2 and flagellin from shiga-toxigenic Escherichia coli superinduce interleukin-8 through synergistic effects on host stress-activated protein kinase activation.Role of tumor necrosis factor alpha in disease using a mouse model of Shiga toxin-mediated renal damage.Shiga toxin regulates its entry in a Syk-dependent manner.Effects of Shiga toxin type 2 on a bioengineered three-dimensional model of human renal tissue.Verotoxin activates mitogen-activated protein kinase in human peripheral blood monocytes: role in apoptosis and proinflammatory cytokine release.Endoplasmic reticulum stress-mediated activation of p38 MAPK, Caspase-2 and Caspase-8 leads to abrin-induced apoptosis.Shiga toxins: intracellular trafficking to the ER leading to activation of host cell stress responses.Different types of cell death induced by enterotoxins.Differential response of the human renal proximal tubular epithelial cell line HK-2 to Shiga toxin types 1 and 2.Shiga toxins induce autophagy leading to differential signalling pathways in toxin-sensitive and toxin-resistant human cells.Uses for JNK: the many and varied substrates of the c-Jun N-terminal kinases.Pro-Coagulant Endothelial Dysfunction Results from EHEC Shiga Toxins and Host Damage-Associated Molecular PatternsSimultaneous induction of apoptotic and survival signaling pathways in macrophage-like THP-1 cells by Shiga toxin 1Protection of rat intestinal epithelial cells from ischemia/reperfusion injury by (D-Ala2, D-Leu5)-enkephalin through inhibition of the MKK7-JNK signaling pathway.
P2860
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P2860
Shiga toxin 1 triggers a ribotoxic stress response leading to p38 and JNK activation and induction of apoptosis in intestinal epithelial cells
description
2003 nî lūn-bûn
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2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
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2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
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name
Shiga toxin 1 triggers a ribot ...... in intestinal epithelial cells
@ast
Shiga toxin 1 triggers a ribot ...... in intestinal epithelial cells
@en
Shiga toxin 1 triggers a ribot ...... in intestinal epithelial cells
@nl
type
label
Shiga toxin 1 triggers a ribot ...... in intestinal epithelial cells
@ast
Shiga toxin 1 triggers a ribot ...... in intestinal epithelial cells
@en
Shiga toxin 1 triggers a ribot ...... in intestinal epithelial cells
@nl
prefLabel
Shiga toxin 1 triggers a ribot ...... in intestinal epithelial cells
@ast
Shiga toxin 1 triggers a ribot ...... in intestinal epithelial cells
@en
Shiga toxin 1 triggers a ribot ...... in intestinal epithelial cells
@nl
P2093
P2860
P1476
Shiga toxin 1 triggers a ribot ...... in intestinal epithelial cells
@en
P2093
Anne V Kane
Brent H Cochran
Cheleste M Thorpe
David W K Acheson
Sausan T Campbell
Wendy E Smith
P2860
P304
P356
10.1128/IAI.71.3.1497-1504.2003
P407
P577
2003-03-01T00:00:00Z