Selection and fine-tuning of the autoimmune T-cell repertoire.
about
CD4+CD25+ immunoregulatory T cells may not be involved in controlling autoimmune arthritisStructure of a TCR with high affinity for self-antigen reveals basis for escape from negative selectionDevelopment of innate CD4+ alpha-chain variable gene segment 24 (Valpha24) natural killer T cells in the early human fetal thymus is regulated by IL-7Manipulating antigenic ligand strength to selectively target myelin-reactive CD4+ T cells in EAE.The basis of T-cell-mediated immunity to chronic myelogenous leukemia.Dendritic cells under investigation in autoimmune disease.Regulator T cells: specific for antigen and/or antigen receptors?Antigen-tailored therapy based on the inflammatory theory of atherosclerosis.Enhanced expression of interferon-gamma-induced antigen-processing machinery components in a spontaneously occurring cancer.Targeting T lymphocytes for immune monitoring and intervention in autoimmune diabetes.Characterization of genetically modified T-cell receptors that recognize the CEA:691-699 peptide in the context of HLA-A2.1 on human colorectal cancer cells.Targeting the TCR: T-cell receptor and peptide-specific tolerance-based strategies for restoring self-tolerance in CNS autoimmune disease.Trial watch: Prognostic and predictive value of the immune infiltrate in cancerT-cell avidity and tuning: the flexible connection between tolerance and autoimmunity.Mechanisms of action of immune tolerance induction against factor VIII in patients with congenital haemophilia A and factor VIII inhibitors.Control of T cell antigen reactivity via programmed TCR downregulation.Apoptotic signal transduction and T cell tolerance.Searching for alternative hematopoietic stem cell donors for pediatric patients.Alloreactivity of virus-specific T cells: possible implication of graft-versus-host disease and graft-versus-leukemia effects.Effects of triptolide from Radix Tripterygium wilfordii (Leigongteng) on cartilage cytokines and transcription factor NF-kappaB: a study on induced arthritis in ratsAltered thymic selection and increased autoimmunity caused by ectopic expression of DRAK2 during T cell developmentMechanisms Underlying CD4+ Treg Immune Regulation in the Adult: From Experiments to ModelsProspects for antigen-specific tolerance based therapies for the treatment of multiple sclerosisA novel mechanism of alternative promoter and splicing regulates the epitope generation of tumor antigen CML66-L.SLAP deficiency increases TCR avidity leading to altered repertoire and negative selection of cognate antigen-specific CD8+ T cells.Theories and quantification of thymic selection.Immunological perspective of self versus tumor antigens: insights from the RIP-gp model.T-cell receptor signaling and the pathogenesis of autoimmune arthritis: insights from mouse and man.Bridging the gap from genetic association to functional understanding: the next generation of mouse models of multiple sclerosis.Functional avidity: a measure to predict the efficacy of effector T cells?Myelin oligodendrocyte glycoprotein induces incomplete tolerance of CD4(+) T cells specific for both a myelin and a neuronal self-antigen in mice.In situ expansion of T cells that recognize distinct self-antigens sustains autoimmunity in the CNS.Molecular mimicry and autoimmune thyroid disease.Heat shock proteins and their immunomodulatory role in inflammatory arthritis.In vivo reprogramming of immune cells: Technologies for induction of antigen-specific tolerance.Generation of functional CD8+ T cells by human dendritic cells expressing glypican-3 epitopes.Presentation of a determinant by MHC class II can be prevented through competitive capture by a flanking determinant on a multideterminant peptideRecognition of a high affinity MHC class I-restricted epitope of myelin oligodendrocyte glycoprotein by CD8⁺ T cells derived from autoantigen-deficient mice.Fibroblastic reticular cells of the lymphoid tissues modulate T cell activation threshold during homeostasis via hyperactive cyclooxygenase-2/prostaglandin E2 axis.Citrullination of self-proteins and autoimmunity.
P2860
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P2860
Selection and fine-tuning of the autoimmune T-cell repertoire.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Selection and fine-tuning of the autoimmune T-cell repertoire.
@ast
Selection and fine-tuning of the autoimmune T-cell repertoire.
@en
Selection and fine-tuning of the autoimmune T-cell repertoire.
@nl
type
label
Selection and fine-tuning of the autoimmune T-cell repertoire.
@ast
Selection and fine-tuning of the autoimmune T-cell repertoire.
@en
Selection and fine-tuning of the autoimmune T-cell repertoire.
@nl
prefLabel
Selection and fine-tuning of the autoimmune T-cell repertoire.
@ast
Selection and fine-tuning of the autoimmune T-cell repertoire.
@en
Selection and fine-tuning of the autoimmune T-cell repertoire.
@nl
P356
P1476
Selection and fine-tuning of the autoimmune T-cell repertoire.
@en
P2093
David C Wraith
Stephen M Anderton
P304
P356
10.1038/NRI842
P577
2002-07-01T00:00:00Z