Disruption of a nonribosomal peptide synthetase in Aspergillus fumigatus eliminates gliotoxin production. - Wikidata - wikimedia - TriplyDB

Disruption of a nonribosomal peptide synthetase in Aspergillus fumigatus eliminates gliotoxin production.

Disruption of a nonribosomal peptide synthetase in Aspergillus fumigatus eliminates gliotoxin production.

http://www.wikidata.org/entity/Q34718528

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Transcriptional regulation of chemical diversity in Aspergillus fumigatus by LaeA Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis GliZ, a transcriptional regulator of gliotoxin biosynthesis, contributes to Aspergillus fumigatus virulence Aspergillus fumigatus: principles of pathogenesis and host defense Advances in Aspergillus secondary metabolite research in the post-genomic era Flavoenzyme-catalyzed formation of disulfide bonds in natural products Biosynthesis and function of gliotoxin in Aspergillus fumigatus Nonribosomal peptide synthetase genes pesL and pes1 are essential for Fumigaclavine C production in Aspergillus fumigatus Aspergillus genomes and the Aspergillus cloud A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus The fumagillin gene cluster, an example of hundreds of genes under veA control in Aspergillus fumigatus Characterization of the Paracoccidioides Hypoxia Response Reveals New Insights into Pathogenesis Mechanisms of This Important Human Pathogenic Fungus Genomic insight into pathogenicity of dematiaceous fungus Corynespora cassiicola Sub-telomere directed gene expression during initiation of invasive aspergillosis Origin and distribution of epipolythiodioxopiperazine (ETP) gene clusters in filamentous ascomycetes.Genomewide screening for genes associated with gliotoxin resistance and sensitivity in Saccharomyces cerevisiae.Aspergillus fumigatus Trehalose-Regulatory Subunit Homolog Moonlights To Mediate Cell Wall Homeostasis through Modulation of Chitin Synthase Activity.Self-protection against gliotoxin--a component of the gliotoxin biosynthetic cluster, GliT, completely protects Aspergillus fumigatus against exogenous gliotoxin Rodent Models of Invasive Aspergillosis due to Aspergillus fumigatus: Still a Long Path toward Standardization.A Nonredundant Phosphopantetheinyl Transferase, PptA, Is a Novel Antifungal Target That Directs Secondary Metabolite, Siderophore, and Lysine Biosynthesis in Aspergillus fumigatus and Is Critical for Pathogenicity.The cross-pathway control system regulates production of the secondary metabolite toxin, sirodesmin PL, in the ascomycete, Leptosphaeria maculans.Regulatory circuitry governing fungal development, drug resistance, and disease.Trehalose 6-phosphate phosphatase is required for cell wall integrity and fungal virulence but not trehalose biosynthesis in the human fungal pathogen Aspergillus fumigatus.A genome-wide survey of the secondary metabolite biosynthesis genes in the wheat pathogen Parastagonospora nodorum.Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus.RNA-seq reveals the pan-transcriptomic impact of attenuating the gliotoxin self-protection mechanism in Aspergillus fumigatus RsmA regulates Aspergillus fumigatus gliotoxin cluster metabolites including cyclo(L-Phe-L-Ser), a potential new diagnostic marker for invasive aspergillosis.Gliotoxin production in Aspergillus fumigatus contributes to host-specific differences in virulence.The small GTPase RacA mediates intracellular reactive oxygen species production, polarized growth, and virulence in the human fungal pathogen Aspergillus fumigatus.What do we know about the role of gliotoxin in the pathobiology of Aspergillus fumigatus?Aspergillus fumigatus and related species.Clinical utility and development of biomarkers in invasive aspergillosis.Mast cell mediator responses and their suppression by pathogenic and commensal microorganisms.Salmonella typhimurium impedes innate immunity with a mast-cell-suppressing protein tyrosine phosphatase, SptP.Nonribosomal peptide synthetases involved in the production of medically relevant natural products.Identification of cryptic products of the gliotoxin gene cluster using NMR-based comparative metabolomics and a model for gliotoxin biosynthesis A novel C2H2 transcription factor that regulates gliA expression interdependently with GliZ in Aspergillus fumigatus.Parallels in fungal pathogenesis on plant and animal hosts.Targeted disruption of nonribosomal peptide synthetase pes3 augments the virulence of Aspergillus fumigatus Genome-based cluster deletion reveals an endocrocin biosynthetic pathway in Aspergillus fumigatus.

P2860

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P2860

Disruption of a nonribosomal peptide synthetase in Aspergillus fumigatus eliminates gliotoxin production.

http://www.wikidata.org/entity/Q34718528

description

2006 nî lūn-bûn

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2006 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2006 թվականի հունիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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name

Disruption of a nonribosomal p ...... iminates gliotoxin production.

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Disruption of a nonribosomal p ...... iminates gliotoxin production.

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Disruption of a nonribosomal p ...... iminates gliotoxin production.

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Disruption of a nonribosomal p ...... iminates gliotoxin production.

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Disruption of a nonribosomal p ...... iminates gliotoxin production.

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Disruption of a nonribosomal p ...... iminates gliotoxin production.

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Disruption of a nonribosomal p ...... iminates gliotoxin production.

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Disruption of a nonribosomal p ...... iminates gliotoxin production.

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Disruption of a nonribosomal p ...... iminates gliotoxin production.

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Eukaryotic Cell

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Carl J Balibar

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John R Graybill

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Laura K Najvar

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Michael P Gamcsik

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Rhea M Brooking

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Robert A Cramer

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Soman N Abraham

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Thomas F Patterson

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William J Steinbach

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William R Kirkpatrick

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P2860

Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

LaeA, a regulator of secondary metabolism in Aspergillus spp

Genetic involvement of a cAMP-dependent protein kinase in a G protein signaling pathway regulating morphological and chemical transitions in Aspergillus nidulans

Aspergillus fumigatus and aspergillosis

Detection of gliotoxin in experimental and human aspergillosis

Tox-boxes, fungal secondary metabolites, and plant disease.

Trends in mortality due to invasive mycotic diseases in the United States, 1980-1997.

Biology and ecology of mycotoxigenic Aspergillus species as related to economic and health concerns.

Aspergillus mycotoxins and their effect on the host.

Epidemiology and outcome of mould infections in hematopoietic stem cell transplant recipients.

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972-980

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10.1128/EC.00049-06

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6

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Aspergillus fumigatus

Nonribosomal peptide synthase (NRPS)

C6 finger domain transcription factor gliZ

Aminotransferase gliI, putative

Dipeptidase gliJ

Nonribosomal peptide synthetase gliP

Cytochrome P450 monooxygenase gliC

O-methyltransferase gliM

Glutathione S-transferase gliG

Gamma-glutamyl cyclotransferase gliK

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1489275

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