Two distinct FUS breakpoint clusters in myxoid liposarcoma and acute myeloid leukemia with the translocations t(12;16) and t(16;21).

Two distinct FUS breakpoint clusters in myxoid liposarcoma and acute myeloid leukemia with the translocations t(12;16) and t(16;21).

Item
http://www.wikidata.org/entity/Q34719993
TLS/FUS, a pro-oncogene involved in multiple chromosomal translocations, is a novel regulator of BCR/ABL-mediated leukemogenesis.Ebp1 sumoylation, regulated by TLS/FUS E3 ligase, is required for its anti-proliferative activity.Molecular strategies for detecting chromosomal translocations in soft tissue tumors (review).Dual transforming activities of the FUS (TLS)-ERG leukemia fusion protein conferred by two N-terminal domains of FUS (TLS).The myxoid/round cell liposarcoma fusion oncogene FUS-DDIT3 and the normal DDIT3 induce a liposarcoma phenotype in transfected human fibrosarcoma cells.Whole genome analyses of a well-differentiated liposarcoma reveals novel SYT1 and DDR2 rearrangements.Specificity of TLS-CHOP rearrangement for classic myxoid/round cell liposarcoma: absence in predominantly myxoid well-differentiated liposarcomas.Induction of a secreted protein by the myxoid liposarcoma oncogeneHSP90 inhibition blocks ERBB3 and RET phosphorylation in myxoid/round cell liposarcoma and causes massive cell death in vitro and in vivo.Whole genome exon arrays identify differential expression of alternatively spliced, cancer-related genes in lung cancer.Differential expression of cysteine dioxygenase 1 in complex karyotype liposarcomas.BCR-ABL prevents c-jun-mediated and proteasome-dependent FUS (TLS) proteolysis through a protein kinase CbetaII-dependent pathway.Myxoid Liposarcoma: Prognostic Factors and Metastatic Pattern in a Series of 148 Patients Treated at a Single Institution.
P2860

Two distinct FUS breakpoint clusters in myxoid liposarcoma and acute myeloid leukemia with the translocations t(12;16) and t(16;21).

Item
http://www.wikidata.org/entity/Q34719993
description
1995 nî lūn-bûn
@nan
1995 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Two distinct FUS breakpoint cl ...... emia with the translocations t
@nl
Two distinct FUS breakpoint cl ...... cations t(12;16) and t(16;21).
@ast
Two distinct FUS breakpoint cl ...... cations t(12;16) and t(16;21).
@en
type
label
Two distinct FUS breakpoint cl ...... emia with the translocations t
@nl
Two distinct FUS breakpoint cl ...... cations t(12;16) and t(16;21).
@ast
Two distinct FUS breakpoint cl ...... cations t(12;16) and t(16;21).
@en
prefLabel
Two distinct FUS breakpoint cl ...... emia with the translocations t
@nl
Two distinct FUS breakpoint cl ...... cations t(12;16) and t(16;21).
@ast
Two distinct FUS breakpoint cl ...... cations t(12;16) and t(16;21).
@en
P1433
P1476
P2093
P304
P31
P407
P433
P478
P50
P577
P698
P921
P1433
P1476
Two distinct FUS breakpoint cl ...... cations t(12;16) and t(16;21).
@en
P2093
P304
P31
P407
P433
P478
P50
P577
P698
P921