Immunization of metastatic breast cancer patients with a fully synthetic globo H conjugate: a phase I trial
about
Dysregulated Expression of Glycolipids in Tumor Cells: From Negative Modulator of Anti-tumor Immunity to Promising Targets for Developing Therapeutic AgentsGlycotherapy: new advances inspire a reemergence of glycans in medicineBreast cancer vaccines: a clinical reality or fairy tale?Development, characterization, and immunotherapeutic use of peptide mimics of the Thomsen-Friedenreich carbohydrate antigen.Protein modifications as potential biomarkers in breast cancer.Metabolic engineering of Agrobacterium sp. strain ATCC 31749 for production of an alpha-Gal epitope.Design and synthesis of potent Quillaja saponin vaccine adjuvantsPreclinical evaluation of the novel monoclonal antibody H6-11 for prostate cancer imaging.Chemoenzymatic Syntheses of Tumor-Associated Carbohydrate Antigen Globo-H and Stage-Specific Embryonic Antigen 4.On the power of chemical synthesis: immunological evaluation of models for multiantigenic carbohydrate-based cancer vaccines.Carbohydrate microarray for profiling the antibodies interacting with Globo H tumor antigen.The glycosphingolipid P₁ is an ovarian cancer-associated carbohydrate antigen involved in migration.A practical total synthesis of globo-H for use in anticancer vaccines.Carbohydrate-based vaccines with a glycolipid adjuvant for breast cancerHuman monoclonal antibodies to sialyl-Lewis (CA19.9) with potent CDC, ADCC, and antitumor activityThe prioritization of cancer antigens: a national cancer institute pilot project for the acceleration of translational research.The case for polyvalent cancer vaccines that induce antibodies.Inhibition of spontaneous breast cancer metastasis by anti-Thomsen-Friedenreich antigen monoclonal antibody JAA-F11Cancer vaccines and carbohydrate epitopes.Recent Development in Carbohydrate Based Anti-cancer Vaccines.Infusion of Sulfosuccinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate-Conjugated MOG35-55-Coupled Spleen Cells Effectively Prevents and Reverses Experimental Autoimmune Encephalomyelitis in MiceA facile method for oxidation of primary alcohols to carboxylic acids and its application in glycosaminoglycan syntheses.Triterpenoid saponins from the roots of Acanthophyllum gypsophiloides Regel.Novel therapeutic approaches for small cell lung cancer: the future has arrivedSequential One-Pot Multienzyme Chemoenzymatic Synthesis of Glycosphingolipid Glycans.Carbohydrate vaccines as immunotherapy for cancer.Antibody repertoire profiling with mimotope arrays.Synthetic carbohydrate-based antitumor vaccines: challenges and opportunities.Towards a therapeutic breast cancer vaccine: the next steps.Posttranslational protein modifications: current implications for cancer detection, prevention, and therapeutics.A Fully Synthetic Self-Adjuvanting Globo H-Based Vaccine Elicited Strong T Cell-Mediated Antitumor Immunity.Breast cancer immunobiology driving immunotherapy: vaccines and immune checkpoint blockade.A Phase I Study of Unimolecular Pentavalent (Globo-H-GM2-sTn-TF-Tn) Immunization of Patients with Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer in First RemissionClustered carbohydrates in synthetic vaccines.Natural and synthetic saponin adjuvant QS-21 for vaccines against cancer.Multi-component one-pot synthesis of the tumor-associated carbohydrate antigen Globo-H based on preactivation of thioglycosyl donors.Vaccine immunotherapy in breast cancer treatment: promising, but still early.Expression of Globo H and SSEA3 in breast cancer stem cells and the involvement of fucosyl transferases 1 and 2 in Globo H synthesis.Glycan antagonists and inhibitors: a fount for drug discovery.Immunization with N-propionyl polysialic acid-KLH conjugate in patients with small cell lung cancer is safe and induces IgM antibodies reactive with SCLC cells and bactericidal against group B meningococci.
P2860
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P2860
Immunization of metastatic breast cancer patients with a fully synthetic globo H conjugate: a phase I trial
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Immunization of metastatic bre ...... o H conjugate: a phase I trial
@ast
Immunization of metastatic bre ...... o H conjugate: a phase I trial
@en
Immunization of metastatic bre ...... o H conjugate: a phase I trial
@nl
type
label
Immunization of metastatic bre ...... o H conjugate: a phase I trial
@ast
Immunization of metastatic bre ...... o H conjugate: a phase I trial
@en
Immunization of metastatic bre ...... o H conjugate: a phase I trial
@nl
prefLabel
Immunization of metastatic bre ...... o H conjugate: a phase I trial
@ast
Immunization of metastatic bre ...... o H conjugate: a phase I trial
@en
Immunization of metastatic bre ...... o H conjugate: a phase I trial
@nl
P2093
P2860
P356
P1476
Immunization of metastatic bre ...... o H conjugate: a phase I trial
@en
P2093
A N Houghton
C Musselli
G Ragupathi
K P Bencsath
K S Panageas
L J Williams
M Spassova
P O Livingston
P2860
P304
P356
10.1073/PNAS.051626298
P407
P50
P577
2001-03-01T00:00:00Z