Ca2+-dependent maturation of subtilisin from a hyperthermophilic archaeon, Thermococcus kodakaraensis: the propeptide is a potent inhibitor of the mature domain but is not required for its folding
about
Crystal structure of unautoprocessed precursor of subtilisin from a hyperthermophilic archaeon: evidence for Ca2+-induced foldingCrystal structure of Tk-subtilisin folded without propeptide: requirement of propeptide for acceleration of foldingIncrease in activation rate of Pro-Tk-subtilisin by a single nonpolar-to-polar amino acid substitution at the hydrophobic core of the propeptide domainAccelerated maturation of Tk-subtilisin by a Leu→Pro mutation at the C-terminus of the propeptide, which reduces the binding of the propeptide to Tk-subtilisinCodon optimisation is key for pernisine expression in Escherichia coliInsights into the maturation of hyperthermophilic pyrolysin and the roles of its N-terminal propeptide and long C-terminal extension.Crystallization and preliminary X-ray diffraction study of an active-site mutant of pro-Tk-subtilisin from a hyperthermophilic archaeonMolecular basis for auto- and hetero-catalytic maturation of a thermostable subtilase from thermophilic Bacillus sp. WF146.Enzymatic activity of a subtilisin homolog, Tk-SP, from Thermococcus kodakarensis in detergents and its ability to degrade the abnormal prion protein.Proteolysis of abnormal prion protein with a thermostable protease from Thermococcus kodakarensis KOD1.Requirement of insertion sequence IS1 for thermal adaptation of Pro-Tk-subtilisin from hyperthermophilic archaeon.Tobacco phytaspase: Successful expression in a heterologous system.In vitro Ca(2+)-dependent maturation of milk-clotting recombinant Epr: minor extracellular protease: from Bacillus licheniformis.An alternative mature form of subtilisin homologue, Tk-SP, from Thermococcus kodakaraensis identified in the presence of Ca2+
P2860
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P2860
Ca2+-dependent maturation of subtilisin from a hyperthermophilic archaeon, Thermococcus kodakaraensis: the propeptide is a potent inhibitor of the mature domain but is not required for its folding
description
2006 nî lūn-bûn
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2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Ca2+-dependent maturation of s ...... s not required for its folding
@ast
Ca2+-dependent maturation of s ...... s not required for its folding
@en
Ca2+-dependent maturation of s ...... s not required for its folding
@nl
type
label
Ca2+-dependent maturation of s ...... s not required for its folding
@ast
Ca2+-dependent maturation of s ...... s not required for its folding
@en
Ca2+-dependent maturation of s ...... s not required for its folding
@nl
prefLabel
Ca2+-dependent maturation of s ...... s not required for its folding
@ast
Ca2+-dependent maturation of s ...... s not required for its folding
@en
Ca2+-dependent maturation of s ...... s not required for its folding
@nl
P2093
P2860
P356
P1476
Ca2+-dependent maturation of s ...... s not required for its folding
@en
P2093
Kenji Saito
Marian Pulido
Shigenori Kanaya
Shun-Ichi Tanaka
Yuichi Koga
P2860
P304
P356
10.1128/AEM.02696-05
P407
P577
2006-06-01T00:00:00Z