C1q deficiency leads to the defective suppression of IFN-alpha in response to nucleoprotein containing immune complexes.
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Breakdown of Immune Tolerance in Systemic Lupus Erythematosus by Dendritic CellsSLE-associated risk factors affect DC functionTLRs and interferons: a central paradigm in autoimmunityCause and consequences of the activated type I interferon system in SLETartrate-resistant acid phosphatase deficiency causes a bone dysplasia with autoimmunity and a type I interferon expression signature.Blood gene expression profiling in pediatric systemic lupus erythematosus and systemic juvenile idiopathic arthritis: from bench to bedside.Evidence for C1q-mediated crosslinking of CD33/LAIR-1 inhibitory immunoreceptors and biological control of CD33/LAIR-1 expression.C1 Complex: An Adaptable Proteolytic Module for Complement and Non-Complement FunctionsMonocyte differentiation and macrophage priming are regulated differentially by pentraxins and their ligandsComplement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.Pivotal Functions of Plasmacytoid Dendritic Cells in Systemic Autoimmune Pathogenesis.The inflammasome and lupus: another innate immune mechanism contributing to disease pathogenesis?Do follicular dendritic cells regulate lupus-specific B cells?Type I interferons are associated with subclinical markers of cardiovascular disease in a cohort of systemic lupus erythematosus patients.Aicardi-Goutières syndrome and the type I interferonopathies.Requirements for innate immune pathways in environmentally induced autoimmunity.C1q-mediated repression of human monocytes is regulated by leukocyte-associated Ig-like receptor 1 (LAIR-1).The type I interferon system in the etiopathogenesis of autoimmune diseases.Type I interferon and systemic lupus erythematosus.Plasmacytoid dendritic cells and C1q differentially regulate inflammatory gene induction by lupus immune complexes.Complement protein C1q directs macrophage polarization and limits inflammasome activity during the uptake of apoptotic cells.C1q protein binds to the apoptotic nucleolus and causes C1 protease degradation of nucleolar proteins.C1q limits dendritic cell differentiation and activation by engaging LAIR-1Genetics of SLE: functional relevance for monocytes/macrophages in diseaseNeutrophil extracellular trap-associated protein activation of the NLRP3 inflammasome is enhanced in lupus macrophagesC1q Modulates the Response to TLR7 Stimulation by Pristane-Primed Macrophages: Implications for Pristane-Induced Lupus.Uncoupling complement C1s activation from C1q binding in apoptotic cell phagocytosis and immunosuppressive capacity.C-reactive protein inhibits plasmacytoid dendritic cell interferon responses to autoantibody immune complexesProteolytic inactivation of nuclear alarmin high-mobility group box 1 by complement protease C1s during apoptosisAnti-DNA antibodies cross-react with C1qType I interferon-mediated monogenic autoinflammation: The type I interferonopathies, a conceptual overviewFueling autoimmunity: type I interferon in autoimmune diseases.The identification of a novel splicing mutation in C1qB in a Japanese family with C1q deficiency: a case report.Assessment of Type I Interferon Signaling in Pediatric Inflammatory Disease.Disease mechanisms in rheumatology--tools and pathways: plasmacytoid dendritic cells and their role in autoimmune rheumatic diseases.Possible novel biomarkers of organ involvement in systemic lupus erythematosus.Beyond apoptosis in lupus.Complement, c1q, and c1q-related molecules regulate macrophage polarization.Systemic Lupus Erythematosus--A Disease with A Dysregulated Type I Interferon System.Insights from Mendelian Interferonopathies: Comparison of CANDLE, SAVI with AGS, Monogenic Lupus.
P2860
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P2860
C1q deficiency leads to the defective suppression of IFN-alpha in response to nucleoprotein containing immune complexes.
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
C1q deficiency leads to the de ...... n containing immune complexes.
@ast
C1q deficiency leads to the de ...... n containing immune complexes.
@en
C1q deficiency leads to the de ...... n containing immune complexes.
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type
label
C1q deficiency leads to the de ...... n containing immune complexes.
@ast
C1q deficiency leads to the de ...... n containing immune complexes.
@en
C1q deficiency leads to the de ...... n containing immune complexes.
@nl
prefLabel
C1q deficiency leads to the de ...... n containing immune complexes.
@ast
C1q deficiency leads to the de ...... n containing immune complexes.
@en
C1q deficiency leads to the de ...... n containing immune complexes.
@nl
P2093
P2860
P356
P1476
C1q deficiency leads to the de ...... n containing immune complexes.
@en
P2093
Brian E Hall
Chih Long Liu
Deanna M Santer
Keith B Elkon
Stephanie Tangsombatvisit
Thaddeus C George
P2860
P304
P356
10.4049/JIMMUNOL.1001731
P407
P577
2010-09-15T00:00:00Z