Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and β cells.
about
Treating type-1 diabetes with an epigenetic drugBET Bromodomain Proteins Brd2, Brd3 and Brd4 Selectively Regulate Metabolic Pathways in the Pancreatic β-Cell.Rapid, high efficiency isolation of pancreatic ß-cells.Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes.Clinical trials for BET inhibitors run ahead of the science.Erythropoiesis provides a BRD's eye view of BET protein function.Concise Review: New Insights Into the Role of Macrophages in β-Cell Proliferation.Epigenetic drug discovery: breaking through the immune barrier.Bromodomain inhibitors and cancer therapy: From structures to applications.Immune disease-associated variants in gene enhancers point to BET epigenetic mechanisms for therapeutic intervention.Epigenetics in the Primary Biliary Cholangitis and Primary Sclerosing Cholangitis.CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells.Measurement of drug-target engagement in live cells by two-photon fluorescence anisotropy imaging.CD122 blockade restores immunological tolerance in autoimmune type 1 diabetes via multiple mechanisms.Interplay between genetic and epigenetic mechanisms in rheumatoid arthritis.Epigenetic control of macrophage polarization: implications for targeting tumor-associated macrophages.
P2860
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P2860
Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and β cells.
description
2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Epigenetic modulation of type- ...... eatic macrophages and β cells.
@ast
Epigenetic modulation of type- ...... eatic macrophages and β cells.
@en
Epigenetic modulation of type- ...... eatic macrophages and β cells.
@nl
type
label
Epigenetic modulation of type- ...... eatic macrophages and β cells.
@ast
Epigenetic modulation of type- ...... eatic macrophages and β cells.
@en
Epigenetic modulation of type- ...... eatic macrophages and β cells.
@nl
prefLabel
Epigenetic modulation of type- ...... eatic macrophages and β cells.
@ast
Epigenetic modulation of type- ...... eatic macrophages and β cells.
@en
Epigenetic modulation of type- ...... eatic macrophages and β cells.
@nl
P2093
P2860
P356
P1433
P1476
Epigenetic modulation of type- ...... eatic macrophages and β cells.
@en
P2093
Christophe Benoist
Diane Mathis
Inmaculada Rioja
Julia Farache
Kimie Hattori
Palwinder Mander
Rab K Prinjha
Susan M Clardy
P2860
P304
P356
10.7554/ELIFE.04631
P407
P577
2014-11-19T00:00:00Z