Novel D-amino acid tetrapeptides produce potent antinociception by selectively acting at peripheral kappa-opioid receptors.
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P-glycoprotein modulates morphine uptake into the CNS: a role for the non-steroidal anti-inflammatory drug diclofenacWill peripherally restricted kappa-opioid receptor agonists (pKORAs) relieve pain with less opioid adverse effects and abuse potential?Peptide kappa opioid receptor ligands: potential for drug development.Spinal or systemic TY005, a peptidic opioid agonist/neurokinin 1 antagonist, attenuates pain with reduced tolerance.Genetic and pharmacological antagonism of NK1 receptor prevents opiate abuse potential.Novel peptide ligands with dual acting pharmacophores designed for the pathophysiology of neuropathic pain.Effects of peripherally restricted κ opioid receptor agonists on pain-related stimulation and depression of behavior in ratsDrug management of visceral pain: concepts from basic research.The effects of C-terminal modifications on the opioid activity of [N-benzylTyr(1)]dynorphin A-(1-11) analogues.Kappa Opioid Receptor-Mediated Disruption of Novel Object Recognition: Relevance for Psychostimulant Treatment.Effects of peripheral κ opioid receptor activation on inflammatory mechanical hyperalgesia in male and female ratsOpioid Peptides: Potential for Drug Development.Neoclerodanes as atypical opioid receptor ligandsAcetaminophen modulates P-glycoprotein functional expression at the blood-brain barrier by a constitutive androstane receptor-dependent mechanismPeripheral mechanisms of pain and analgesia.Angiotensin-(1-7)/Mas receptor as an antinociceptive agent in cancer-induced bone pain.Opioid receptor targeting ligands for pain management: a review and update.Novel fentanyl-based dual μ/δ-opioid agonists for the treatment of acute and chronic pain.Heat-shock protein 90 (Hsp90) promotes opioid-induced anti-nociception by an ERK mitogen-activated protein kinase (MAPK) mechanism in mouse brain.Structure-Activity Relationships of [des-Arg7]Dynorphin A Analogues at the κ Opioid Receptor.Synthesis and activity of endomorphin-2 and morphiceptin analogues with proline surrogates in position 2.Development of a Peptide-derived orally-active kappa-opioid receptor agonist targeting peripheral pain.Design, synthesis, and biological evaluation of a series of bifunctional ligands of opioids/SSRIs.A population pharmacokinetic and pharmacodynamic study of a peripheral κ-opioid receptor agonist CR665 and oxycodone.Antinociceptive potency of a fluorinated cyclopeptide Dmt-c[D-Lys-Phe-p-CF3-Phe-Asp]NH2.
P2860
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P2860
Novel D-amino acid tetrapeptides produce potent antinociception by selectively acting at peripheral kappa-opioid receptors.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Novel D-amino acid tetrapeptid ...... pheral kappa-opioid receptors.
@ast
Novel D-amino acid tetrapeptid ...... pheral kappa-opioid receptors.
@en
Novel D-amino acid tetrapeptid ...... pheral kappa-opioid receptors.
@nl
type
label
Novel D-amino acid tetrapeptid ...... pheral kappa-opioid receptors.
@ast
Novel D-amino acid tetrapeptid ...... pheral kappa-opioid receptors.
@en
Novel D-amino acid tetrapeptid ...... pheral kappa-opioid receptors.
@nl
prefLabel
Novel D-amino acid tetrapeptid ...... pheral kappa-opioid receptors.
@ast
Novel D-amino acid tetrapeptid ...... pheral kappa-opioid receptors.
@en
Novel D-amino acid tetrapeptid ...... pheral kappa-opioid receptors.
@nl
P2093
P1476
Novel D-amino acid tetrapeptid ...... pheral kappa-opioid receptors.
@en
P2093
Claudio Schteingart
Frank Porreca
Frédérique Menzaghi
Jacek Stalewski
Javier Sueiras-Diaz
Jean-Louis Junien
Jerzy Trojnar
Josephine Lai
Pierre J-M Rivière
Richard A Houghten
P356
10.1016/J.EJPHAR.2008.01.011
P407
P577
2008-01-24T00:00:00Z