Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue.
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Induced pluripotent stem cells for cardiovascular disease: from product-focused disease modeling to process-focused disease discoveryHuman iPS cell model of type 3 long QT syndrome recapitulates drug-based phenotype correctionInherited heart disease - what can we expect from the second decade of human iPS cell research?TECRL, a new life-threatening inherited arrhythmia gene associated with overlapping clinical features of both LQTS and CPVTStop-codon and C-terminal nonsense mutations are associated with a lower risk of cardiac events in patients with long QT syndrome type 1.Modeling Inherited Arrhythmia Disorders Using Induced Pluripotent Stem Cell-Derived Cardiomyocytes.Characterization of a novel KCNQ1 mutation for type 1 long QT syndrome and assessment of the therapeutic potential of a novel IKs activator using patient-specific induced pluripotent stem cell-derived cardiomyocytes.Prospects for In Vitro Myofilament Maturation in Stem Cell-Derived Cardiac Myocytes.hiPSC-derived cardiomyocytes from Brugada Syndrome patients without identified mutations do not exhibit clear cellular electrophysiological abnormalitiesA new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells.Functional Studies and In Silico Analyses to Evaluate Non-Coding Variants in Inherited Cardiomyopathies.Cardiomyocytes from human pluripotent stem cells: From laboratory curiosity to industrial biomedical platform.Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells.Genetics of long-QT syndrome.Concise Review: Patient-Derived Stem Cell Research for Monogenic Disorders.From iPSC towards cardiac tissue-a road under construction.Induced pluripotent stem cells: at the heart of cardiovascular precision medicine.Integrating cardiomyocytes from human pluripotent stem cells in safety pharmacology: has the time come?Contractile Defect Caused by Mutation in MYBPC3 Revealed under Conditions Optimized for Human PSC-Cardiomyocyte FunctionConcise Review: Measuring Physiological Responses of Human Pluripotent Stem Cell Derived Cardiomyocytes to Drugs and Disease.Genome Editing for the Study of Cardiovascular Diseases.Perspectives and Challenges of Pluripotent Stem Cells in Cardiac Arrhythmia Research.Human heart disease: lessons from human pluripotent stem cell-derived cardiomyocytes.Human iPSC-Derived Cardiomyocytes for Investigation of Disease Mechanisms and Therapeutic Strategies in Inherited Arrhythmia Syndromes: Strengths and Limitations.Cardiac Subtype-Specific Modeling of Kv1.5 Ion Channel Deficiency Using Human Pluripotent Stem Cells.Universal cardiac induction of human pluripotent stem cells in two and three-dimensional formats: implications for in vitro maturation.Human iPS cell models of Jervell and Lange-Nielsen syndrome.Patch-Clamp Recording from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Improving Action Potential Characteristics through Dynamic Clamp.Human pluripotent stem cell models of cardiac disease: from mechanisms to therapies.Adrenergic Stress Protection of Human iPS Cell-Derived Cardiomyocytes by Fast Kv7.1 Recycling.Reply to Christ et al.: LQT1 and JLNS phenotypes in hiPSC-derived cardiomyocytes are due to KCNQ1 mutationsLQT1-phenotypes in hiPSC: Are we measuring the right thing?Potassium channels in the heart: structure, function and regulation.Genome Editing: The Recent History and Perspective in Cardiovascular Diseases.Drug-Mediated Shortening of Action Potentials in LQTS2 Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo.Human Pluripotent Stem Cell Differentiation into Functional Epicardial Progenitor Cells.Simplified footprint-free Cas9/CRISPR editing of cardiac-associated genes in human pluripotent stem cells.The Impact of CRISPR/Cas9 Technology on Cardiac Research: From Disease Modelling to Therapeutic Approaches.Low Resting Membrane Potential and Low Inward Rectifier Potassium Currents Are Not Inherent Features of hiPSC-Derived Cardiomyocytes.
P2860
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P2860
Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue.
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Recessive cardiac phenotypes i ...... ms and pharmacological rescue.
@ast
Recessive cardiac phenotypes i ...... ms and pharmacological rescue.
@en
Recessive cardiac phenotypes i ...... ms and pharmacological rescue.
@nl
type
label
Recessive cardiac phenotypes i ...... ms and pharmacological rescue.
@ast
Recessive cardiac phenotypes i ...... ms and pharmacological rescue.
@en
Recessive cardiac phenotypes i ...... ms and pharmacological rescue.
@nl
prefLabel
Recessive cardiac phenotypes i ...... ms and pharmacological rescue.
@ast
Recessive cardiac phenotypes i ...... ms and pharmacological rescue.
@en
Recessive cardiac phenotypes i ...... ms and pharmacological rescue.
@nl
P2093
P2860
P50
P356
P1476
Recessive cardiac phenotypes i ...... ms and pharmacological rescue.
@en
P2093
Christian Freund
Cristina D'Aniello
Dorien Ward-van Oostwaard
Douwe E Atsma
Eric Schulze-Bahr
Eva Wrobel
Guiscard Seebohm
Ilaria Piccini
Miao Zhang
Stefan Frank
P2860
P304
P356
10.1073/PNAS.1419553111
P407
P577
2014-12-01T00:00:00Z