LIM kinase 1 modulates cortical actin and CXCR4 cycling and is activated by HIV-1 to initiate viral infection.
about
Protein kinase C-delta regulates HIV-1 replication at an early post-entry step in macrophagesGelsolin activity controls efficient early HIV-1 infectionβ-arrestin-dependent activation of the cofilin pathway is required for the scavenging activity of the atypical chemokine receptor D6CDC42 Use in Viral Cell Entry Processes by RNA VirusesHIV restriction in quiescent CD4⁺ T cellsHow HIV takes advantage of the cytoskeleton in entry and replicationLIM kinase/cofilin dysregulation promotes macrothrombocytopenia in severe von Willebrand disease-type 2B.CCR5/CD4/CXCR4 oligomerization prevents HIV-1 gp120IIIB binding to the cell surfaceROCK1 and LIM kinase modulate retrovirus particle release and cell-cell transmission eventsEzrin is a component of the HIV-1 virological presynapse and contributes to the inhibition of cell-cell fusion.HIV persistence: chemokines and their signalling pathways.Discovery of Novel Small-Molecule Inhibitors of LIM Domain Kinase for Inhibiting HIV-1HIV entry and envelope glycoprotein-mediated fusionBis-aryl urea derivatives as potent and selective LIM kinase (Limk) inhibitors.Viral exploitation of actin: force-generation and scaffolding functions in viral infection.Quantitative analysis of the processes and signaling events involved in early HIV-1 infection of T cells.How HIV-1 takes advantage of the cytoskeleton during replication and cell-to-cell transmissionSpinoculation triggers dynamic actin and cofilin activity that facilitates HIV-1 infection of transformed and resting CD4 T cells.Evidence for the involvement of cofilin in Aspergillus fumigatus internalization into type II alveolar epithelial cells.Cannabinoid receptor 2-mediated attenuation of CXCR4-tropic HIV infection in primary CD4+ T cellsThe trinity of the cortical actin in the initiation of HIV-1 infectionInvolvement of LIM kinase 1 in actin polarization in human CD4 T cells.A dichotomy in cortical actin and chemotactic actin activity between human memory and naive T cells contributes to their differential susceptibility to HIV-1 infectionMolecular determinants of the ratio of inert to infectious virus particles.N-terminal Slit2 inhibits HIV-1 replication by regulating the actin cytoskeleton.Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization.Genistein interferes with SDF-1- and HIV-mediated actin dynamics and inhibits HIV infection of resting CD4 T cells.The cortical actin determines different susceptibility of naïve and memory CD4+ T cells to HIV-1 cell-to-cell transmission and infection.Novel anti-HIV therapeutics targeting chemokine receptors and actin regulatory pathwaysImpairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization.HIV-1 triggers WAVE2 phosphorylation in primary CD4 T cells and macrophages, mediating Arp2/3-dependent nuclear migration.Viral infection: Moving through complex and dynamic cell-membrane structures.Rho kinase inhibitors: a patent review (2012 - 2013).Rho'ing in and out of cells: viral interactions with Rho GTPase signalingPIP2: choreographer of actin-adaptor proteins in the HIV-1 dance.Pathogenic microbes manipulate cofilin activity to subvert actin cytoskeleton.Subverting Host Cell P21-Activated Kinase: A Case of Convergent Evolution across Pathogens.Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4+ T Cells In Vitro.Alphaherpesviral US3 kinase induces cofilin dephosphorylation to reorganize the actin cytoskeleton.Role of Drebrin at the Immunological Synapse.
P2860
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P2860
LIM kinase 1 modulates cortical actin and CXCR4 cycling and is activated by HIV-1 to initiate viral infection.
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
LIM kinase 1 modulates cortica ...... 1 to initiate viral infection.
@ast
LIM kinase 1 modulates cortica ...... 1 to initiate viral infection.
@en
LIM kinase 1 modulates cortica ...... 1 to initiate viral infection.
@nl
type
label
LIM kinase 1 modulates cortica ...... 1 to initiate viral infection.
@ast
LIM kinase 1 modulates cortica ...... 1 to initiate viral infection.
@en
LIM kinase 1 modulates cortica ...... 1 to initiate viral infection.
@nl
prefLabel
LIM kinase 1 modulates cortica ...... 1 to initiate viral infection.
@ast
LIM kinase 1 modulates cortica ...... 1 to initiate viral infection.
@en
LIM kinase 1 modulates cortica ...... 1 to initiate viral infection.
@nl
P2093
P2860
P356
P1476
LIM kinase 1 modulates cortica ...... 1 to initiate viral infection.
@en
P2093
Alyson Yoder
Dongyang Yu
Mark Spear
Paul J Vorster
Weifeng Wang
Yanfang Zheng
P2860
P304
12554-12564
P356
10.1074/JBC.M110.182238
P407
P577
2011-02-14T00:00:00Z