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Digitoxin and its analogs as novel cancer therapeuticsDigitoxin and a synthetic monosaccharide analog inhibit cell viability in lung cancer cellsReal-time analysis of the effects of toxic, therapeutic and sub-therapeutic concentrations of digitoxin on lung cancer cellsMonosaccharide digitoxin derivative sensitize human non-small cell lung cancer cells to anoikis through Mcl-1 proteasomal degradationPilot study of huachansu in patients with hepatocellular carcinoma, nonsmall-cell lung cancer, or pancreatic cancerTargeting hypoxic response for cancer therapyIdentification of novel p53 pathway activating small-molecule compounds reveals unexpected similarities with known therapeutic agentsIdentification of known drugs that act as inhibitors of NF-kappaB signaling and their mechanism of actionEvaluating the cancer therapeutic potential of cardiac glycosidesInfluence of Sugar Amine Regiochemistry on Digitoxigenin Neoglycoside Anticancer ActivityInactivation of Src-to-ezrin pathway: a possible mechanism in the ouabain-mediated inhibition of A549 cell migrationTrial watch: Cardiac glycosides and cancer therapyA Direct Comparison of the Anticancer Activities of Digitoxin MeON-Neoglycosides and O-Glycosides: Oligosaccharide Chain Length-Dependent Induction of Caspase-9-Mediated ApoptosisConvallatoxin, a dual inducer of autophagy and apoptosis, inhibits angiogenesis in vitro and in vivoNovel stereoselective bufadienolides reveal new insights into the requirements for Na(+), K(+)-ATPase inhibition by cardiotonic steroidsAutosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia.Digoxin and other cardiac glycosides inhibit HIF-1alpha synthesis and block tumor growth.Digoxin use and risk of invasive breast cancer: evidence from the Nurses' Health Study and meta-analysis.Ex vivo activity of cardiac glycosides in acute leukaemia.Identification of small-molecule inhibitors of the colorectal cancer oncogene Krüppel-like factor 5 expression by ultrahigh-throughput screeningSignaling mechanisms that link salt retention to hypertension: endogenous ouabain, the Na(+) pump, the Na(+)/Ca(2+) exchanger and TRPC proteins.Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheresUnveiling new biological relationships using shared hits of chemical screening assay pairsPro-death and pro-survival properties of ouabain in U937 lymphoma derived cellsToxicarioside A inhibits tumor growth and angiogenesis: involvement of TGF-β/endoglin signalingCardenolides of Leptadenia madagascariensis from the Madagascar dry forest.Activity of BK(Ca) channel is modulated by membrane cholesterol content and association with Na+/K+-ATPase in human melanoma IGR39 cells.Endogenous cardiotonic steroids: physiology, pharmacology, and novel therapeutic targets.Neuroprotective effects of lutein in the retinaStereochemical survey of digitoxin monosaccharides: new anticancer analogues with enhanced apoptotic activity and growth inhibitory effect on human non-small cell lung cancer cell.Cytotoxic cardiac glycosides and coumarins from Antiaris toxicaria.Effects of bilberry on deoxyribonucleic Acid damage and oxidant-antioxidant balance in the lens, induced by ultraviolet radiation.Involvement of general control nonderepressible kinase 2 in cancer cell apoptosis by posttranslational mechanisms.Cancer as a channelopathy: ion channels and pumps in tumor development and progressionPBI-05204, a supercritical CO₂ extract of Nerium oleander, inhibits growth of human pancreatic cancer via targeting the PI3K/mTOR pathwayA novel two-stage, transdisciplinary study identifies digoxin as a possible drug for prostate cancer treatment.Cellular location and expression of Na+, K+ -ATPase α subunits affect the anti-proliferative activity of oleandrin.Asymmetric synthesis of dihydroindanes by convergent alkoxide-directed metallacycle-mediated bond formation.Steroid Receptor Coactivator-3 (SRC-3/AIB1) as a Novel Therapeutic Target in Triple Negative Breast Cancer and Its Inhibition with a Phospho-Bufalin Prodrug.Toxicarioside A inhibits SGC-7901 proliferation, migration and invasion via NF-κB/bFGF signaling.
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
name
Cardiac glycosides as novel cancer therapeutic agents.
@ast
Cardiac glycosides as novel cancer therapeutic agents.
@en
Cardiac glycosides as novel cancer therapeutic agents.
@nl
type
label
Cardiac glycosides as novel cancer therapeutic agents.
@ast
Cardiac glycosides as novel cancer therapeutic agents.
@en
Cardiac glycosides as novel cancer therapeutic agents.
@nl
prefLabel
Cardiac glycosides as novel cancer therapeutic agents.
@ast
Cardiac glycosides as novel cancer therapeutic agents.
@en
Cardiac glycosides as novel cancer therapeutic agents.
@nl
P2093
P356
P1476
Cardiac glycosides as novel cancer therapeutic agents.
@en
P2093
Alison D Pawlus
Peiying Yang
Robert A Newman
P356
10.1124/MI.8.1.8
P577
2008-02-01T00:00:00Z