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Nicotinic acetylcholine receptors as targets for antidepressants.

Nicotinic acetylcholine receptors as targets for antidepressants.

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Discovery of novel alpha7 nicotinic receptor antagonists Nicotinic receptor mechanisms and cognition in normal states and neuropsychiatric disorders.Chemistry and pharmacology of nicotinic ligands based on 6-[5-(azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol (AMOP-H-OH) for possible use in depression Nicotine receptors and depression: revisiting and revising the cholinergic hypothesis No evidence for association between 19 cholinergic genes and bipolar disorder Neurochemistry of the nucleus accumbens and its relevance to depression and antidepressant action in rodents Depression and smoking cessation: does the evidence support psychiatric practice?Bacoside A: Role in Cigarette Smoking Induced Changes in Brain Targeting the noradrenergic system for gender-sensitive medication development for tobacco dependence Two decades of smoking cessation treatment research on smokers with depression: 1990-2010 Molecules and circuits involved in nicotine addiction: The many faces of smoking Mecamylamine (Inversine): an old antihypertensive with new research directions Mecamylamine - a nicotinic acetylcholine receptor antagonist with potential for the treatment of neuropsychiatric disorders Study of a mechanism responsible for potential antidepressant activity of EMD 386088, a 5-HT6 partial agonist in rats Stable expression and functional characterization of a human nicotinic acetylcholine receptor with α6β2 properties: discovery of selective antagonists nAChR dysfunction as a common substrate for schizophrenia and comorbid nicotine addiction: Current trends and perspectives.How cigarette smoking may increase the risk of anxiety symptoms and anxiety disorders: a critical review of biological pathways.Nicotinic receptor-mediated reduction in L-DOPA-induced dyskinesias may occur via desensitization Subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: evidence from genetically modified mice.Social defeat, a paradigm of depression in rats that elicits 22-kHz vocalizations, preferentially activates the cholinergic signaling pathway in the periaqueductal gray Imbalance of glial-neuronal interaction in synapses: a possible mechanism of the pathophysiology of bipolar disorder.Down-regulation of cholinergic signaling in the habenula induces anhedonia-like behavior.In search of allosteric modulators of a7-nAChR by solvent density guided virtual screening.Quantification of methyllycaconitine, selective α7 nicotinic receptor antagonist, in rodent plasma and brain tissue by liquid chromatography tandem mass spectrometry--application to neuropharmacokinetics of methyllycaconitine in rats.Functional brain imaging of nicotinic effects on higher cognitive processes.Adolescent smoking and depression: evidence for self-medication and peer smoking mediation.Differential effects of TRPV1 receptor ligands against nicotine-induced depression-like behaviors.Inhibition of G protein-activated inwardly rectifying K+ channels by different classes of antidepressants.Pharmacology of nicotine: addiction, smoking-induced disease, and therapeutics Chemistry and pharmacological characterization of novel nitrogen analogues of AMOP-H-OH (Sazetidine-A, 6-[5-(azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol) as α4β2-nicotinic acetylcholine receptor-selective partial agonists.Semisynthetic analogues of toxiferine I and their pharmacological properties at α7 nAChRs, muscle-type nAChRs, and the allosteric binding site of muscarinic M2 receptors.The potent and selective α4β2*/α6*-nicotinic acetylcholine receptor partial agonist 2-[5-[5-((S)Azetidin-2-ylmethoxy)-3-pyridinyl]-3-isoxazolyl]ethanol demonstrates antidepressive-like behavior in animal models and a favorable ADME-tox profile.Recent developments in novel antidepressants targeting α4β2-nicotinic acetylcholine receptors.Function of partially duplicated human α77 nicotinic receptor subunit CHRFAM7A gene: potential implications for the cholinergic anti-inflammatory response.Functional nicotinic acetylcholine receptors containing α6 subunits are on GABAergic neuronal boutons adherent to ventral tegmental area dopamine neurons.Nicotine and nicotinic receptor antagonists potentiate the antidepressant-like effects of imipramine and citalopram.The catecholaminergic-cholinergic balance hypothesis of bipolar disorder revisited.Expression of the 5-HT1A serotonin receptor in the hippocampus is required for social stress resilience and the antidepressant-like effects induced by the nicotinic partial agonist cytisine Topical mecamylamine for diabetic macular edema Naturally-expressed nicotinic acetylcholine receptor subtypes.

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Nicotinic acetylcholine receptors as targets for antidepressants.

http://www.wikidata.org/entity/Q34761238

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Nicotinic acetylcholine receptors as targets for antidepressants.

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Nicotinic acetylcholine receptors as targets for antidepressants.

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Nicotinic acetylcholine receptors as targets for antidepressants.

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Nicotinic acetylcholine receptors as targets for antidepressants.

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Nicotinic acetylcholine receptors as targets for antidepressants.

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Nicotinic acetylcholine receptors as targets for antidepressants.

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Nicotinic acetylcholine receptors as targets for antidepressants.

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Nicotinic acetylcholine receptors as targets for antidepressants.

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Molecular Psychiatry

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Nicotinic acetylcholine receptors as targets for antidepressants

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P2860

The catecholamine hypothesis of affective disorders: a review of supporting evidence

Activation and inhibition of rat neuronal nicotinic receptors by ABT-418

Mecamylamine: new therapeutic uses and toxicity/risk profile

Cigarette smoking and major depression

Depression and the dynamics of smoking. A national perspective

Smoking, smoking cessation, and major depression

Tianeptine, a selective enhancer of serotonin uptake in rat brain

Effect of lithium on the physostigmine-induced behavioral syndrome and plasma cyclic GMP

Dose-related neuroprotective effects of chronic nicotine in 6-hydroxydopamine treated rats, and loss of neuroprotection in alpha4 nicotinic receptor subunit knockout mice

Multicenter, placebo-controlled, fixed-dose study of citalopram in moderate-to-severe depression

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