The diarylheptanoid (+)-aR,11S-myricanol and two flavones from bayberry (Myrica cerifera) destabilize the microtubule-associated protein tau.
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Myricetin: A Dietary Molecule with Diverse Biological ActivitiesRecent Breakthroughs in the Antioxidant and Anti-Inflammatory Effects of Morella and Myrica SpeciesSynthesis, stereochemical analysis, and derivatization of myricanol provide new probes that promote autophagic tau clearance.Biological Activities of Triterpenoids and Phenolic Compounds from Myrica cerifera Bark.Pathological Tau Promotes Neuronal Damage by Impairing Ribosomal Function and Decreasing Protein SynthesisNatural products as a rich source of tau-targeting drugs for Alzheimer's disease.Identification of Novel Tau Interactions with Endoplasmic Reticulum Proteins in Alzheimer's Disease Brain.Inhibition of Both Hsp70 Activity and Tau Aggregation in Vitro Best Predicts Tau Lowering Activity of Small Molecules.Strained cyclophane natural products: macrocyclization at its limits.Phenotypic screens targeting neurodegenerative diseases.A twist of nature--the significance of atropisomers in biological systems.Myricanol induces apoptotic cell death and anti-tumor activity in non-small cell lung carcinoma in vivo.Chaperone-dependent Neurodegeneration: A Molecular Perspective on Therapeutic Intervention.Diarylheptanoid Glycosides of Morella salicifolia Bark.Current Screening Methodologies in Drug Discovery for Selected Human Diseases
P2860
Q26764901-06EDC0B6-BE6B-413E-9270-2CB205FC88B7Q26796670-FE4C4948-674A-41D3-AE9C-5EB8F75F52DBQ35542753-68C62A53-98D9-4474-90A9-8156882C62D7Q36095451-6CEBD7A9-E975-468F-A619-ABD59CE6C989Q36480214-788212FC-5DB8-42C0-B6E8-8AF0A6828A0BQ36617889-6BB69E73-3F1A-46CF-811C-03B393EC1149Q36939900-10AA9FAC-1053-4A83-A3D7-3778AE2910C6Q37417421-C13B2D01-5CCB-477E-A43A-B34B4B13673EQ38021350-45790178-494E-4660-BA4B-79EF8AD32DCAQ38130052-3D9AF288-CD0D-478A-94CA-2E290BEE5545Q38568605-AF23BD38-F1D7-4B5C-B1CB-E33A01DE6C39Q38915760-751D65EF-90EC-4E99-9D14-2E97EE0D55FDQ41786144-52F96637-C832-4185-B126-FE566F410EA1Q47283696-E6CD1059-01AE-447C-BED6-5A34976257E1Q57169512-C9492A57-B64A-4841-BF1A-9F72EC6C7777
P2860
The diarylheptanoid (+)-aR,11S-myricanol and two flavones from bayberry (Myrica cerifera) destabilize the microtubule-associated protein tau.
description
2010 nî lūn-bûn
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2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
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2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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name
The diarylheptanoid (+)-aR,11S ...... tubule-associated protein tau.
@ast
The diarylheptanoid (+)-aR,11S ...... tubule-associated protein tau.
@en
The diarylheptanoid (+)-aR,11S ...... tubule-associated protein tau.
@nl
type
label
The diarylheptanoid (+)-aR,11S ...... tubule-associated protein tau.
@ast
The diarylheptanoid (+)-aR,11S ...... tubule-associated protein tau.
@en
The diarylheptanoid (+)-aR,11S ...... tubule-associated protein tau.
@nl
prefLabel
The diarylheptanoid (+)-aR,11S ...... tubule-associated protein tau.
@ast
The diarylheptanoid (+)-aR,11S ...... tubule-associated protein tau.
@en
The diarylheptanoid (+)-aR,11S ...... tubule-associated protein tau.
@nl
P2093
P2860
P356
P1476
The diarylheptanoid (+)-aR,11S ...... tubule-associated protein tau.
@en
P2093
Amelia G Johnson
Bill J Baker
Chad A Dickey
Christopher B Eckman
Edwin Weeber
Jeffrey R Jones
John C O'Leary
John Koren
Jose F Abisambra
Justin Trotter
P2860
P356
10.1021/NP100572Z
P577
2010-12-08T00:00:00Z