about
15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancersPromoter methylation status of hMLH1, MGMT, and CDKN2A/p16 in colorectal adenomasWnt signaling in cancer stem cells and colon cancer metastasisIntegrated genomic analysis of colorectal cancer progression reveals activation of EGFR through demethylation of the EREG promoterThe aberrant methylation of TSP1 suppresses TGF-beta1 activation in colorectal cancer.Aberrant DNA methylation occurs in colon neoplasms arising in the azoxymethane colon cancer modelModulation of epigenetic targets for anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectivesCadherin-bound beta-catenin feeds into the Wnt pathway upon adherens junctions dissociation: evidence for an intersection between beta-catenin pools.Epigenetic mechanisms of promigratory chemokine CXCL14 regulation in human prostate cancer cells.Smad4-mediated TGF-beta signaling in tumorigenesis.Gastrointestinal tract cancers: Genetics, heritability and germ line mutationsHuman RAS superfamily proteins and related GTPases.Transforming growth factor beta (TGF-beta) and inflammation in cancer.Genomic and epigenetic instability in colorectal cancer pathogenesis.Synthetic triterpenoid induces 15-PGDH expression and suppresses inflammation-driven colon carcinogenesis.Heterozygous TGFBR2 mutations in Marfan syndromeGenome-wide screening of genes regulated by DNA methylation in colon cancer development.Identification of common microRNA-mRNA regulatory biomodules in human epithelial cancers.Colorectal cancer "methylator phenotype": fact or artifact?The novel colorectal cancer biomarkers CDO1, ZSCAN18 and ZNF331 are frequently methylated across gastrointestinal cancersA Sleeping Beauty transposon-mediated screen identifies murine susceptibility genes for adenomatous polyposis coli (Apc)-dependent intestinal tumorigenesisDown-regulation of c9orf86 in human breast cancer cells inhibits cell proliferation, invasion and tumor growth and correlates with survival of breast cancer patientsNOB1 is essential for the survival of RKO colorectal cancer cellsEssential role of CR6-interacting factor 1 (Crif1) in E74-like factor 3 (ELF3)-mediated intestinal developmentThe not-so innocent bystander: the microenvironment as a therapeutic target in cancer.Development of primary early-onset colorectal cancers due to biallelic mutations of the FANCD1/BRCA2 geneInhibition of apoptosis in normal and transformed intestinal epithelial cells by cAMP through induction of inhibitor of apoptosis protein (IAP)-2The MDM2 promoter polymorphism SNP309T-->G and the risk of uterine leiomyosarcoma, colorectal cancer, and squamous cell carcinoma of the head and neckRAS Mutations and Oncogenesis: Not all RAS Mutations are Created Equally.JMJD5 is a potential oncogene for colon carcinogenesis.Modelling oncogenic Ras/Raf signalling in the mouse.Expression of a novel immunoglobulin gene SNC73 in human cancer and non-cancerous tissuesAbrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis.Associations of Ki-ras proto-oncogene mutation and p53 gene overexpression in sporadic colorectal adenomas with demographic and clinicopathologic characteristics.Point mutations of protein kinases and individualised cancer therapy.Enhanced intestinal tumor multiplicity and grade in vivo after HZE exposure: mouse models for space radiation risk estimatesGenetic testing for colon cancer.DNA alkylation and DNA methylation: cooperating mechanisms driving the formation of colorectal adenomas and adenocarcinomas?Reversibility of aberrant global DNA and estrogen receptor-alpha gene methylation distinguishes colorectal precancer from cancer.Genetic variation in 15-hydroxyprostaglandin dehydrogenase and colon cancer susceptibility.
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Genetic and epigenetic alterations in colon cancer.
@ast
Genetic and epigenetic alterations in colon cancer.
@en
Genetic and epigenetic alterations in colon cancer.
@nl
type
label
Genetic and epigenetic alterations in colon cancer.
@ast
Genetic and epigenetic alterations in colon cancer.
@en
Genetic and epigenetic alterations in colon cancer.
@nl
prefLabel
Genetic and epigenetic alterations in colon cancer.
@ast
Genetic and epigenetic alterations in colon cancer.
@en
Genetic and epigenetic alterations in colon cancer.
@nl
P1476
Genetic and epigenetic alterations in colon cancer.
@en
P2093
Sanford D Markowitz
William M Grady
P304
P356
10.1146/ANNUREV.GENOM.3.022502.103043
P577
2002-04-15T00:00:00Z