LPK-26, a novel kappa-opioid receptor agonist with potent antinociceptive effects and low dependence potential.

LPK-26, a novel kappa-opioid receptor agonist with potent antinociceptive effects and low dependence potential.

Item
http://www.wikidata.org/entity/Q34763263
The G protein-biased κ-opioid receptor agonist RB-64 is analgesic with a unique spectrum of activities in vivoNovel κ-opioid receptor agonist MB-1C-OH produces potent analgesia with less depression and sedationCollybolide is a novel biased agonist of κ-opioid receptors with potent antipruritic activityMetabolic changes in the rodent brain after acute administration of salvinorin A.Adenosine A(1) receptor agonist N(6)-cyclohexyl-adenosine induced phosphorylation of delta opioid receptor and desensitization of its signaling.The role of kappa-opioid receptor activation in mediating antinociception and addiction.Identification of novel functionally selective κ-opioid receptor scaffolds.NMR structure and dynamics of the agonist dynorphin peptide bound to the human kappa opioid receptorEffects of peripheral κ opioid receptor activation on inflammatory mechanical hyperalgesia in male and female ratsAnalgesic activity of some 1,2,4-triazole heterocycles clubbed with pyrazole, tetrazole, isoxazole and pyrimidine.Effects of ATPM-ET, a novel κ agonist with partial μ activity, on physical dependence and behavior sensitization in mice.Opioid receptor targeting ligands for pain management: a review and update.Pharmacological characterization of ATPM [(-)-3-aminothiazolo[5,4-b]-N-cyclopropylmethylmorphinan hydrochloride], a novel mixed kappa-agonist and mu-agonist/-antagonist that attenuates morphine antinociceptive tolerance and heroin self-administratioAttenuation of morphine tolerance and dependence by thymoquinone in miceInduction of hyperphagia and carbohydrate intake by μ-opioid receptor stimulation in circumscribed regions of frontal cortex.Heteromers of μ opioid and dopamine D1 receptors modulate opioid-induced locomotor sensitization in a dopamine-independent manner.Discovery, stereospecific characterization and peripheral modification of 1-(pyrrolidin-1-ylmethyl)-2-[(6-chloro-3-oxo-indan)-formyl]-1,2,3,4-tetrahydroisoquinolines as novel selective κ opioid receptor agonists.
P2860

LPK-26, a novel kappa-opioid receptor agonist with potent antinociceptive effects and low dependence potential.

Item
http://www.wikidata.org/entity/Q34763263
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
LPK-26, a novel kappa-opioid r ...... and low dependence potential.
@ast
LPK-26, a novel kappa-opioid r ...... and low dependence potential.
@en
LPK-26, a novel kappa-opioid r ...... and low dependence potential.
@nl
type
label
LPK-26, a novel kappa-opioid r ...... and low dependence potential.
@ast
LPK-26, a novel kappa-opioid r ...... and low dependence potential.
@en
LPK-26, a novel kappa-opioid r ...... and low dependence potential.
@nl
prefLabel
LPK-26, a novel kappa-opioid r ...... and low dependence potential.
@ast
LPK-26, a novel kappa-opioid r ...... and low dependence potential.
@en
LPK-26, a novel kappa-opioid r ...... and low dependence potential.
@nl
P1433
P1476
P2093
P304
P31
P356
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P478
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P698
P921
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P1433
P1476
LPK-26, a novel kappa-opioid r ...... and low dependence potential.
@en
P2093
P304
P31
P356
10.1016/J.EJPHAR.2008.02.028
P407
P433
P478
P577
P698
P921