Polypeptide N-acetylgalactosaminyltransferase 6 disrupts mammary acinar morphogenesis through O-glycosylation of fibronectin - Wikidata - wikimedia - TriplyDB

Polypeptide N-acetylgalactosaminyltransferase 6 disrupts mammary acinar morphogenesis through O-glycosylation of fibronectin

Polypeptide N-acetylgalactosaminyltransferase 6 disrupts mammary acinar morphogenesis through O-glycosylation of fibronectin

http://www.wikidata.org/entity/Q34763642

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Role of Glycans in Cancer Cells Undergoing Epithelial-Mesenchymal Transition Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene family Protein glycosylation in cancers and its potential therapeutic applications in neuroblastoma C1GALT1 promotes invasive phenotypes of hepatocellular carcinoma cells by modulating integrin β1 glycosylation and activity Increase of O-glycosylated oncofetal fibronectin in high glucose-induced epithelial-mesenchymal transition of cultured human epithelial cells.GALNT2 suppresses malignant phenotypes through IGF-1 receptor and predicts favorable prognosis in neuroblastoma.Involvement of O-glycosylation defining oncofetal fibronectin in epithelial-mesenchymal transition process The interconnectedness of cancer cell signaling.Up-regulation of C1GALT1 promotes breast cancer cell growth through MUC1-C signaling pathway Probing isoform-specific functions of polypeptide GalNAc-transferases using zinc finger nuclease glycoengineered SimpleCells The lectin domain of the polypeptide GalNAc transferase family of glycosyltransferases (ppGalNAc Ts) acts as a switch directing glycopeptide substrate glycosylation in an N- or C-terminal direction, further controlling mucin type O-glycosylation Polypeptide N-acetylgalactosaminyl transferase 3 independently predicts high-grade tumours and poor prognosis in patients with renal cell carcinomas.Cancer subclonal genetic architecture as a key to personalized medicine.N-acetylgalactosaminyltransferases in cancer.Polypeptide N-acetylgalactosaminyltransferase-6 expression independently predicts poor overall survival in patients with lung adenocarcinoma after curative resection The Cosmc connection to the Tn antigen in cancer.Precision genome editing: a small revolution for glycobiology.Lectins as probes for assessing the accessibility of N-linked glycans in relation to the conformational changes of fibronectin.Biosynthetic Machinery Involved in Aberrant Glycosylation: Promising Targets for Developing of Drugs Against Cancer Loss of N-Acetylgalactosaminyltransferase-4 Orchestrates Oncogenic MicroRNA-9 in Hepatocellular Carcinoma.Specific N-glycan alterations are coupled in EMT induced by different density cultivation of MCF 10A epithelial cells.Specific N-glycan alterations are coupled in epithelial-mesenchymal transition induced by EGF in GE11 epithelial cells.GalNAc-T6 in the relationship with invasion ability of endometrial carcinomas and prognostic significance.GalNAc-T4 putatively modulates the estrogen regulatory network through FOXA1 glycosylation in human breast cancer cells.COSMC knockdown mediated aberrant O-glycosylation promotes oncogenic properties in pancreatic cancer.GALNT14 mediates tumor invasion and migration in breast cancer cell MCF-7.Excess APP O-glycosylation by GalNAc-T6 decreases Aβ production.Induction of epithelial-mesenchymal transition with O-glycosylated oncofetal fibronectin.Polypeptide N-acetylgalactosaminyltransferase-6 expression in gastric cancer.Relevance of βGal-βGalNAc-containing glycans and the enzymes involved in their synthesis for invasion and survival in breast cancer patients.Biological and biochemical properties of two Xenopus laevis N-acetylgalactosaminyltransferases with contrasting roles in embryogenesis.Overcoming intratumor heterogeneity of polygenic cancer drug resistance with improved biomarker integration Pivotal role of MUC1 glycosylation by cigarette smoke in modulating disruption of airway adherens junctions in vitro GALNT6 expression enhances aggressive phenotypes of ovarian cancer cells by regulating EGFR activity.The molecular chaperone Cosmc enhances malignant behaviors of colon cancer cells via activation of Akt and ERK.De novo expression of human polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) in colon adenocarcinoma inhibits the differentiation of colonic epithelium.Core 3 mucin-type O-glycan restoration in colorectal cancer cells promotes MUC1/p53/miR-200c-dependent epithelial identity.Polypeptide-GalNAc-T6 expression predicts better overall survival in patients with colon cancer.O-linked mucin-type glycosylation in breast cancer Critical Role of Estrogen Receptor Alpha O-Glycosylation by N-Acetylgalactosaminyltransferase 6 (GALNT6) in Its Nuclear Localization in Breast Cancer Cells

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P2860

Polypeptide N-acetylgalactosaminyltransferase 6 disrupts mammary acinar morphogenesis through O-glycosylation of fibronectin

http://www.wikidata.org/entity/Q34763642

description

2011 nî lūn-bûn

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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Polypeptide N-acetylgalactosam ...... O-glycosylation of fibronectin

@ast

Polypeptide N-acetylgalactosam ...... O-glycosylation of fibronectin

@en

Polypeptide N-acetylgalactosam ...... O-glycosylation of fibronectin

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type

label

Polypeptide N-acetylgalactosam ...... O-glycosylation of fibronectin

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Polypeptide N-acetylgalactosam ...... O-glycosylation of fibronectin

@en

Polypeptide N-acetylgalactosam ...... O-glycosylation of fibronectin

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prefLabel

Polypeptide N-acetylgalactosam ...... O-glycosylation of fibronectin

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Polypeptide N-acetylgalactosam ...... O-glycosylation of fibronectin

@en

Polypeptide N-acetylgalactosam ...... O-glycosylation of fibronectin

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Polypeptide N-acetylgalactosam ...... O-glycosylation of fibronectin

@en

P2093

Jae-Hyun Park

http://www.w3.org/2001/XMLSchema#string

Kyoko Kijima

http://www.w3.org/2001/XMLSchema#string

Suyoun Chung

http://www.w3.org/2001/XMLSchema#string

Toyomasa Katagiri

http://www.w3.org/2001/XMLSchema#string

Yusuke Nakamura

http://www.w3.org/2001/XMLSchema#string

P2860

Clathrin-mediated endocytosis of MUC1 is modulated by its glycosylation state

Fibronectin expression modulates mammary epithelial cell proliferation during acinar differentiation

The epithelial-mesenchymal transition: new insights in signaling, development, and disease

Cloning and characterization of a close homologue of human UDP-N-acetyl-alpha-D-galactosamine:Polypeptide N-acetylgalactosaminyltransferase-T3, designated GalNAc-T6. Evidence for genetic but not functional redundancy

Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

Akt1 governs breast cancer progression in vivo.

Mucin-type O-glycosylation--putting the pieces together.

Fibronectin matrix turnover occurs through a caveolin-1-dependent process.

Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL.

All in the family: the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases.

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320-326

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scholarly article

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10.1593/NEO.101440

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4

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13

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2011-04-01T00:00:00Z

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51031418

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21472136

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3071080

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