Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis.
about
Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of IkarosRole of Ikaros in T-cell acute lymphoblastic leukemiaEndogenous retroviral promoter exaptation in human cancerA Snail1/Notch1 signalling axis controls embryonic vascular development.Illegitimate V(D)J recombination-mediated deletions in Notch1 and Bcl11b are not sufficient for extensive clonal expansion and show minimal age or sex bias in frequency or junctional processing.Enhanced Notch activation is advantageous but not essential for T cell lymphomagenesis in Id1 transgenic miceConstitutive Notch pathway activation in murine ZMYM2-FGFR1-induced T-cell lymphomas associated with atypical myeloproliferative disease.Ikaros-Notch axis in host hematopoietic cells regulates experimental graft-versus-host disease.Nonoverlapping functions for Notch1 and Notch3 during murine steady-state thymic lymphopoiesis.Repression of Ccr9 transcription in mouse T lymphocyte progenitors by the Notch signaling pathway.An Ikaros Promoter Element with Dual Epigenetic and Transcriptional Activities.Epigenetics of Notch1 regulation in pulmonary microvascular rarefaction following extrauterine growth restriction.HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT).Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical updateAlternative Splice Variants Modulates Dominant-Negative Function of Helios in T-Cell Leukemia.GATA-1 utilizes Ikaros and polycomb repressive complex 2 to suppress Hes1 and to promote erythropoiesisSet3 HDAC mediates effects of overlapping noncoding transcription on gene induction kinetics.Ikaros inhibits megakaryopoiesis through functional interaction with GATA-1 and NOTCH signalingActivated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia.PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL.Transcriptional regulation of the Ikzf1 locus.Modulation of mRNA and lncRNA expression dynamics by the Set2-Rpd3S pathway.Targeting signal transduction pathways of cancer stem cells for therapeutic opportunities of metastasis.Multifactorial ERβ and NOTCH1 control of squamous differentiation and cancer.Proteolytic cleavage of Notch: "HIT and RUN".Therapeutic potential of Notch inhibition in T-cell acute lymphoblastic leukemia: rationale, caveats and promises.Expression of different functional isoforms in haematopoiesis.Ikaros fingers on lymphocyte differentiation.Harnessing of the nucleosome-remodeling-deacetylase complex controls lymphocyte development and prevents leukemogenesis.Dynamic usage of alternative splicing exons during mouse retina developmentA novel isoform of IL-33 revealed by screening for transposable element promoted genes in human colorectal cancerThe molecular pathogenesis of chronic lymphocytic leukaemia.Crucial role of the Rap G protein signal in Notch activation and leukemogenicity of T-cell acute lymphoblastic leukemiaLoss of IP3R-dependent Ca2+ signalling in thymocytes leads to aberrant development and acute lymphoblastic leukemia.The making of a lymphocyte: the choice among disparate cell fates and the IKAROS enigma.High mobility group A1 protein acts as a new target of Notch1 signaling and regulates cell proliferation in T leukemia cells.Fingerprinting ikarosIkaros: master of hematopoiesis, agent of leukemia.Dynamic transformations of genome-wide epigenetic marking and transcriptional control establish T cell identity.Common nonmutational NOTCH1 activation in chronic lymphocytic leukemia.
P2860
Q24607867-6AD59B67-1E01-42D9-84F5-63754A590336Q24633359-373279A9-4533-4BB9-9734-78F5CCBAFB04Q28067477-C58809C3-03DF-4AB5-B0FA-47EFECF9D348Q33736954-DB667A86-9349-4725-BEA0-DAAB0AA7A1A6Q33821742-A3D68A6E-F6C0-4C34-B6A1-46C68914003AQ34186057-6DC2C986-81D9-4927-9FE9-696B9B1B3BFFQ35083254-B57946F5-6619-476D-897B-BA49F313140EQ35114506-E021E7B3-C24D-4BBA-8AEF-651AD7B4AA29Q35197387-77372F4B-23C9-4FE5-88AA-7DBA2568A47EQ35205379-954EBE26-D0A7-467D-B0F3-8EF6047F8082Q35680998-380A111C-989B-4CF3-A35E-A89F97C8FB8BQ35800561-6C9C51F6-45AB-415E-9FF0-539B62FDFAF2Q35886890-4E0D266A-B6B9-4F9E-86A3-21833057F3D4Q35904534-CC2A7987-AF5E-4E9B-A775-2AAF932DAC3BQ36147014-6A81F489-79E4-441E-975A-2B9FF4D7A91EQ36197098-DA39CA7B-8455-43D8-AF90-7659B271E431Q36287609-32A7A311-29DE-4A1E-A70C-00D5384E1FBEQ36730409-86AD6DA4-9870-4E63-9750-E343F1C36AD6Q36837426-3E2D5A59-00A9-4C6F-80AF-9D2904B9B8E2Q36920819-6B15F3A2-4ACD-4A8A-91FA-CC737C95BEE3Q37272025-DB2659C7-88FA-4AAA-A1AB-2B1972321F23Q37465086-266B0839-D60B-46EE-8199-9744BE400917Q37689120-583FCC31-EE08-47CB-AC42-A5152EFDBAE5Q37728495-DA5F2818-83EB-4F88-A542-1C22DC769987Q37867140-ACD6F621-09B6-4CDA-BFCB-AF8DEAD09D55Q37934968-C1E66755-2E79-41B7-9B4E-9509AA8789DDQ38167700-DD2215EB-2265-4F98-9A24-17C02A8371FBQ38236141-8B2E9EA1-651E-47FA-922E-6FE92F893AEAQ38461429-DA0ABAE1-3E8D-4C70-901B-4F7C016E6FA3Q38612755-38A76FD2-6DBB-4098-9912-DD753768C26FQ38675614-09E00148-7028-4373-B5E9-91F1345BA181Q38748645-AC458E16-092D-4452-BBC9-333BC4EDCF97Q38917376-56F93BB3-12A2-424F-9F4B-4098DE1C8A5AQ38957223-E01ED238-13D0-487F-82C6-DBD30A9DF5F6Q39225226-C8EC989E-1CB6-4F44-B649-158FF7C621F9Q39228428-2CB14ED9-6B8B-485D-9319-8C7137DC46E8Q41850635-DB44640A-21ED-42FB-AEAB-A6BEFFE46F1DQ42057738-3252D5E5-7A82-4560-88EA-8415143ADD1CQ42136153-75693806-FEDA-4D0D-BE22-0DEF04D3D02EQ42291852-D7BE6990-6803-4497-BB20-7DF53A33E542
P2860
Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis.
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Alternative promoter usage at ...... evelopment and leukemogenesis.
@ast
Alternative promoter usage at ...... evelopment and leukemogenesis.
@en
Alternative promoter usage at ...... evelopment and leukemogenesis.
@nl
type
label
Alternative promoter usage at ...... evelopment and leukemogenesis.
@ast
Alternative promoter usage at ...... evelopment and leukemogenesis.
@en
Alternative promoter usage at ...... evelopment and leukemogenesis.
@nl
prefLabel
Alternative promoter usage at ...... evelopment and leukemogenesis.
@ast
Alternative promoter usage at ...... evelopment and leukemogenesis.
@en
Alternative promoter usage at ...... evelopment and leukemogenesis.
@nl
P2093
P2860
P50
P1433
P1476
Alternative promoter usage at ...... development and leukemogenesis
@en
P2093
Audrey F Jackson
Barbara Kee
Feifei Liu
Jiangwen Zhang
Katia Georgopoulos
Marc Vooijs
Mariko Kashiwagi
Taku Naito
P2860
P304
P356
10.1016/J.IMMUNI.2010.11.008
P407
P577
2010-11-01T00:00:00Z