Homeoprotein Six1 increases TGF-beta type I receptor and converts TGF-beta signaling from suppressive to supportive for tumor growth. - Wikidata - wikimedia - TriplyDB

Homeoprotein Six1 increases TGF-beta type I receptor and converts TGF-beta signaling from suppressive to supportive for tumor growth.

Homeoprotein Six1 increases TGF-beta type I receptor and converts TGF-beta signaling from suppressive to supportive for tumor growth.

http://www.wikidata.org/entity/Q34768886

about

The retinal determination gene network: from developmental regulator to cancer therapeutic target The Three Paralogous MicroRNA Clusters in Development and Disease, miR-17-92, miR-106a-363, and miR-106b-25 Targeting the Transforming Growth Factor-β Signaling in Cancer Therapy Switching Roles of TGF-β in Cancer Development: Implications for Therapeutic Target and Biomarker Studies Interplay of retinal determination gene network with TGF-β signaling pathway in epithelial-mesenchymal transition Histone deacetylase inhibitor induces the expression of select epithelial genes in mouse utricle sensory epithelia-derived progenitor cells.Six1 expression is associated with a poor prognosis in patients with glioma Two faces of TGF-beta1 in breast cancer.Increased Six1 expression is associated with poor prognosis in patients with osteosarcoma.Inflammation and Epithelial-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma: Fighting Against Multiple Opponents Six1 promotes epithelial-mesenchymal transition and malignant conversion in human papillomavirus type 16-immortalized human keratinocytes.Interferon consensus sequence-binding protein (ICSBP) promotes epithelial-to-mesenchymal transition (EMT)-like phenomena, cell-motility, and invasion via TGF-β signaling in U2OS cells.HOXA9 promotes homotypic and heterotypic cell interactions that facilitate ovarian cancer dissemination via its induction of P-cadherin Meta-analysis of gene expression signatures defining the epithelial to mesenchymal transition during cancer progression Cyclic AMP enhances TGFβ responses of breast cancer cells by upregulating TGFβ receptor I expression.Six1 overexpression at early stages of HPV16-mediated transformation of human keratinocytes promotes differentiation resistance and EMT.TGF-β signaling in breast cancer cell invasion and bone metastasis.The SIX1-EYA transcriptional complex as a therapeutic target in cancer.Eya2 is required to mediate the pro-metastatic functions of Six1 via the induction of TGF-β signaling, epithelial-mesenchymal transition, and cancer stem cell properties.Cofilin drives cell-invasive and metastatic responses to TGF-β in prostate cancer.SIX1 induces lymphangiogenesis and metastasis via upregulation of VEGF-C in mouse models of breast cancer The miR-106b-25 cluster targets Smad7, activates TGF-β signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer.PPARδ promotes oncogenic redirection of TGF-β1 signaling through the activation of the ABCA1-Cav1 pathway.The metastasis-promoting roles of tumor-associated immune cells Deconstructing the mechanisms and consequences of TGF-β-induced EMT during cancer progression.The relevance of the TGF-β Paradox to EMT-MET programs SIX1 maintains tumor basal cells via transforming growth factor-β pathway and associates with poor prognosis in esophageal cancer.Transforming growth factor-β signaling in tumor initiation, progression and therapy in breast cancer: an update.Six1: a critical transcription factor in tumorigenesis.Homeobox Gene Deregulation: Impact on the Hallmarks of Cancer The multifaceted role of the embryonic gene Cripto-1 in cancer, stem cells and epithelial-mesenchymal transition.SIX1 promotes epithelial-mesenchymal transition in colorectal cancer through ZEB1 activation.Molecular insights into tumour metastasis: tracing the dominant events.EMT promoting transcription factors as prognostic markers in human breast cancer.Inhibition of Six1 promotes apoptosis, suppresses proliferation, and migration of osteosarcoma cells.Increased expression of Six1 correlates with progression and prognosis of prostate cancer.CDK3, target of miR-4469, suppresses breast cancer metastasis via inhibiting Wnt/β-catenin pathway.DNA methylation is a key factor in understanding differentiation phenotype in esophageal squamous cell carcinoma.The regulation of cytokine signaling by retinal determination gene network pathway in cancer

P2860

Q26747218-FF1E4139-7D4E-41E1-AB65-AFEEE8DB795B Q26748969-1D8D41A8-997A-4D2D-94DA-7D6975D73B49 Q27021750-BB740F42-35E6-496C-9E12-3F0D3EF4FF0B Q28079488-9098E20E-3593-4295-BD47-27165592E21A Q28088611-ED7A9824-2A97-480B-B959-74BC3E8655A1 Q30405625-21E49FCD-7267-4EC2-930B-61525871820B Q33597712-19773AE8-F473-43DC-A13B-ACA7BA27DCDC Q33661529-DA55A3A8-9258-4B4E-BDB7-D9CF9B0D0157 Q33684857-E9E18F38-A21A-4CBB-8506-7518A029773B Q33704284-32D925C4-2D16-4B39-B7D9-1BBE732139F6 Q33705247-49BAB583-9EB6-4872-8B0A-D4D1ADDB152C Q33720109-7B120D87-8649-4D5A-8F09-643E5F30AC47 Q33927161-80E6C514-E778-40A5-8E0D-4F3C3D52EB2D Q34516160-7F1866DE-19CC-4381-8197-296BB6DAB74A Q34562845-E01A3EB9-9979-491C-B5F4-0A198F1FDE1C Q34657109-AB30B9E9-8560-44F0-B499-B959F7C55719 Q34985004-D76C6731-444B-4708-8065-2DD02F273E7A Q35107900-0971488B-9E17-44A0-887F-8B3EA1B777FC Q35243673-16002E5F-E529-4AF6-A5BE-9C1A683A2AE4 Q35806990-1CD7DE08-ECDD-43B5-8BE8-883BFABDA9D8 Q35913687-5EE55876-607E-4C43-9EFB-8957A596A9A2 Q35928749-254157C6-9829-4211-975E-B720CDF4ADB0 Q36923329-19E7FC30-25F0-4D1D-BEA9-4119F4F87CA0 Q36972016-B803F9C9-10E1-4A00-8AC5-FA782094948B Q37044614-5A95ABB3-8A24-4B07-BFAD-18EAB8CAA354 Q37118399-3E6120C8-5F27-4335-BD6C-7A7198184872 Q37670690-16817CF3-1A50-4D73-8C08-C54C69F1799D Q37918451-E1BBE82F-D1D0-46DB-9872-662CDC8E4AC5 Q38184513-CBA5707D-05F1-453B-B2A4-CCC3B76A0496 Q38206779-57E658E4-B306-4306-A32D-83845CC342E7 Q38242892-EEF70AAE-AA34-41FF-9070-16D5710F47F8 Q38328202-254FCC53-A3C6-4744-8EF5-F228B1A38CD8 Q38776336-4E0A7B09-A7C2-4C9D-B006-3BD0292267CD Q38965324-776B15D8-958E-4FE6-A008-462D68A6B590 Q39082476-16568CB0-7974-46C2-9EB1-75EC0E5C76CC Q41175001-F760671A-9FA7-4094-B0EE-5F4C0C1A302E Q43951442-304ADD7F-964E-43BD-875A-FD80851085A9 Q53662194-9EE55553-72FE-43F4-9224-7B683263A254 Q57483942-8CEE4AD2-8057-4B7A-807D-7DCDD38476AA

P2860

Homeoprotein Six1 increases TGF-beta type I receptor and converts TGF-beta signaling from suppressive to supportive for tumor growth.

http://www.wikidata.org/entity/Q34768886

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Homeoprotein Six1 increases TG ...... o supportive for tumor growth.

@ast

Homeoprotein Six1 increases TG ...... o supportive for tumor growth.

@en

Homeoprotein Six1 increases TG ...... o supportive for tumor growth.

@nl

type

label

Homeoprotein Six1 increases TG ...... o supportive for tumor growth.

@ast

Homeoprotein Six1 increases TG ...... o supportive for tumor growth.

@en

Homeoprotein Six1 increases TG ...... o supportive for tumor growth.

@nl

prefLabel

Homeoprotein Six1 increases TG ...... o supportive for tumor growth.

@ast

Homeoprotein Six1 increases TG ...... o supportive for tumor growth.

@en

Homeoprotein Six1 increases TG ...... o supportive for tumor growth.

@nl

P1433

Q34768886-D00A80E3-90E2-4F9B-9D67-FF366330611F

P1476

Q34768886-1BAA4160-6848-4313-B210-04D7BB3BBC06

P2093

Q34768886-75D8058E-8064-4630-BDC7-9154D2F943A2

Q34768886-C52A55E6-7A8D-4295-B49B-793E5FD0F7CE

Q34768886-DB9D7B3B-6D92-4939-82C3-0E14BBCDB956

Q34768886-E905644D-5CD5-4A5A-923C-D9C2CD98BF14

Q34768886-F5416CCF-444D-46FD-A115-A174E2965BA4

P2860

Q34768886-00715D5E-EBA2-4055-8802-DE9B69386C01

Q34768886-10A51288-0C77-4A4F-A81A-75C22DFE6176

Q34768886-1313F25E-B9CF-4F74-8601-138B2F251FA0

Q34768886-18CFC334-94A0-4BE6-9117-C791F21C4474

Q34768886-1FBABD94-AAC7-4639-A12F-010A54BD9AEC

Q34768886-23EB9A18-BC8C-4464-A9B1-DDE354B18F99

Q34768886-250B3122-F502-48B5-91B9-D6487C3DE027

Q34768886-25653626-8B6C-4429-852D-DD1800995B38

Q34768886-27638128-1ABE-4B8C-AAC4-780150CA7970

Q34768886-2ED1D1C0-48C0-4243-92AA-078859017D7D

P304

Q34768886-02B0F061-A611-499E-9EA1-BECF70088F8F

P31

Q34768886-C2120FC8-0DD3-4174-BCE5-CFAB937F4CA1

P356

Q34768886-DF4C8441-6FB1-4DDD-9696-5A5B3057348F

P407

Q34768886-B6B05D61-A4DB-43F7-BB5F-115C953A7305

P433

Q34768886-48C31207-E7D7-4994-A7EA-367D72AE7518

P478

Q34768886-59739DA7-90AC-4AA9-B9EB-EDAED7F7DEFD

P577

Q34768886-EF8579A7-A424-4DCE-AD23-EBF0FD399416

P698

Q34768886-66938681-AB3D-43AF-9E66-42DEE6B7E810

P932

Q34768886-8994CE68-B7B7-42B3-88A4-3AFE358488C1

P356

0008-5472.CAN-10-1354

P1433

Cancer Research

P1476

Homeoprotein Six1 increases TG ...... o supportive for tumor growth.

@en

P2093

Chu-An Wang

http://www.w3.org/2001/XMLSchema#string

Douglas S Micalizzi

http://www.w3.org/2001/XMLSchema#string

Heide L Ford

http://www.w3.org/2001/XMLSchema#string

Susan M Farabaugh

http://www.w3.org/2001/XMLSchema#string

William P Schiemann

http://www.w3.org/2001/XMLSchema#string

P2860

The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1

Abrogation of the G2 cell cycle checkpoint associated with overexpression of HSIX1: a possible mechanism of breast carcinogenesis

Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites

Role of transforming growth factor beta in human disease

Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis

Altered myogenesis in Six1-deficient mice

Six1 is required for the early organogenesis of mammalian kidney

Ligand-specific function of transforming growth factor beta in epithelial-mesenchymal transition in heart development

Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site

Six1 and Six4 homeoproteins are required for Pax3 and Mrf expression during myogenesis in the mouse embryo

P304

10371-10380

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1158/0008-5472.CAN-10-1354

http://www.w3.org/2001/XMLSchema#string

P407

P433

24

http://www.w3.org/2001/XMLSchema#string

P478

70

http://www.w3.org/2001/XMLSchema#string

P577

2010-11-05T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

21056993

http://www.w3.org/2001/XMLSchema#string

P932

3072046

http://www.w3.org/2001/XMLSchema#string