The nucleobase-ascorbate transporter (NAT) family: genomics, evolution, structure-function relationships and physiological role.
about
Molecular dynamics simulations of the bacterial UraA H+-uracil symporter in lipid bilayers reveal a closed state and a selective interaction with cardiolipinStructure and mechanism of the uracil transporter UraAUnknown components of the plastidial permeome.Expression, purification and low-resolution structure of human vitamin C transporter SVCT1 (SLC23A1)Small RNA profiling of virus-infected grapevines: evidences for virus infection-associated and variety-specific miRNAs.Purine substrate recognition by the nucleobase-ascorbate transporter signature motif in the YgfO xanthine permease: ASN-325 binds and ALA-323 senses substrateNucleobase and nucleoside transport and integration into plant metabolismCysteine-scanning analysis of helices TM8, TM9a, and TM9b and intervening loops in the YgfO xanthine permease: a carboxyl group is essential at ASP-276.Insights to the evolution of Nucleobase-Ascorbate Transporters (NAT/NCS2 family) from the Cys-scanning analysis of xanthine permease XanQIdentification of the substrate recognition and transport pathway in a eukaryotic member of the nucleobase-ascorbate transporter (NAT) familyOrigin, diversification and substrate specificity in the family of NCS1/FUR transporters.Vitamin C transporters.The invertebrate Caenorhabditis elegans biosynthesizes ascorbate.Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus.Functional identification of SLC43A3 as an equilibrative nucleobase transporter involved in purine salvage in mammals.Purine utilization by Klebsiella oxytoca M5al: genes for ring-oxidizing and -opening enzymes.Nucleoside/nucleobase transporters: drug targets of the future?Highlights from recently determined structures of membrane proteins: a focus on channels and transporters.Understanding transporter specificity and the discrete appearance of channel-like gating domains in transporters.Assessing cancer cell migration and metastatic growth in vivo in the chick embryo using fluorescence intravital imaging.Identification and functional characterization of the first nucleobase transporter in mammals: implication in the species difference in the intestinal absorption mechanism of nucleobases and their analogs between higher primates and other mammalsStructure of eukaryotic purine/H(+) symporter UapA suggests a role for homodimerization in transport activity.The solute specificity profiles of nucleobase cation symporter 1 (NCS1) from Zea mays and Setaria viridis illustrate functional flexibility.Dimeric structure of the uracil:proton symporter UraA provides mechanistic insights into the SLC4/23/26 transporters.Lipid interaction sites on channels, transporters and receptors: Recent insights from molecular dynamics simulations.Role of intramembrane polar residues in the YgfO xanthine permease: HIS-31 and ASN-93 are crucial for affinity and specificity, and ASP-304 and GLU-272 are irreplaceable.Modeling, substrate docking, and mutational analysis identify residues essential for the function and specificity of a eukaryotic purine-cytosine NCS1 transporter.Role of YiaX2 in L-ascorbate transport in Klebsiella pneumoniae 13882.The arrestin-like protein ArtA is essential for ubiquitination and endocytosis of the UapA transporter in response to both broad-range and specific signals.Conformational transitions of uracil transporter UraA from Escherichia coli: a molecular simulation study.Cryptic purine transporters in Aspergillus nidulans reveal the role of specific residues in the evolution of specificity in the NCS1 family.Evolution of substrate specificity in the Nucleobase-Ascorbate Transporter (NAT) protein family.
P2860
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P2860
The nucleobase-ascorbate transporter (NAT) family: genomics, evolution, structure-function relationships and physiological role.
description
2008 nî lūn-bûn
@nan
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The nucleobase-ascorbate trans ...... nships and physiological role.
@ast
The nucleobase-ascorbate trans ...... nships and physiological role.
@en
The nucleobase-ascorbate trans ...... nships and physiological role.
@nl
type
label
The nucleobase-ascorbate trans ...... nships and physiological role.
@ast
The nucleobase-ascorbate trans ...... nships and physiological role.
@en
The nucleobase-ascorbate trans ...... nships and physiological role.
@nl
prefLabel
The nucleobase-ascorbate trans ...... nships and physiological role.
@ast
The nucleobase-ascorbate trans ...... nships and physiological role.
@en
The nucleobase-ascorbate trans ...... nships and physiological role.
@nl
P2860
P356
P1433
P1476
The nucleobase-ascorbate trans ...... onships and physiological role
@en
P2093
Ioannis Papageorgiou
P2860
P304
P356
10.1039/B719777B
P577
2008-03-11T00:00:00Z