Methylation reveals a niche: stem cell succession in human colon crypts.
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Animal cell differentiation patterns suppress somatic evolutionDeficient expression of DNA repair enzymes in early progression to sporadic colon cancerGenomic variability within an organism exposes its cell lineage treeDeficient Pms2, ERCC1, Ku86, CcOI in field defects during progression to colon cancerAldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesisTracing ancestry with methylation patterns: most crypts appear distantly related in normal adult human colonField cancerisation in colorectal cancer: a new frontier or pastures past?Heterogeneity of the level of activity of lgr5+ intestinal stem cellsStem cells and colorectal carcinogenesisStem cell dynamics and pretumor progression in the intestinal tractAn empty Drosophila stem cell niche reactivates the proliferation of ectopic cellsAging-Induced Stem Cell Mutations as Drivers for Disease and CancerAberrant intestinal stem cell lineage dynamics in Peutz-Jeghers syndrome and familial adenomatous polyposis consistent with protracted clonal evolution in the cryptDrosophila midgut homeostasis involves neutral competition between symmetrically dividing intestinal stem cellsEpigenetic inactivation of the NORE1 gene correlates with malignant progression of colorectal tumorsWidespread and tissue specific age-related DNA methylation changes in mice.A stem cell niche dominance theorem.Role of heterozygous APC mutation in niche succession and initiation of colorectal cancer--a computational studyMitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission.A single cell bioengineering approach to elucidate mechanisms of adult stem cell self-renewal.Cell organisation in the colonic crypt: a theoretical comparison of the pedigree and niche concepts.Enhanced stem cell survival in familial adenomatous polyposis.Pretumor progression: clonal evolution of human stem cell populations.Organ aging and susceptibility to cancer may be related to the geometry of the stem cell niche.Evidence of the monoclonal composition of human endometrial epithelial glands and mosaic pattern of clonal distribution in luminal epithelium.Epigenetic dysregulation in laryngeal squamous cell carcinoma.Cardiac stem cells and mechanisms of myocardial regeneration.From gene mutations to tumours--stem cells in gastrointestinal carcinogenesis.Crypt dynamics and colorectal cancer: advances in mathematical modelling.Mechanisms of disease: from stem cells to colorectal cancer.Tales from the crypt.Developmentally programmed 3' CpG island methylation confers tissue- and cell-type-specific transcriptional activationReview paper: Implications of the "cancer stem cell" hypothesis on murine models of colon cancer and colitis-associated cancer.APC and its modifiers in colon cancer.Stem cells and their implications for colorectal cancer.Mutational Heterogeneity in APC and KRAS Arises at the Crypt Level and Leads to Polyclonality in Early Colorectal Tumorigenesis.FOXP3 inhibits cancer stem cell self-renewal via transcriptional repression of COX2 in colorectal cancer cells.Microdevice to capture colon crypts for in vitro studies.Longitudinal analysis of colon crypt stem cell dynamics in sulindac treated Familial Adenomatous Polyposis patients.The 'stem cell' concept: is it holding us back?
P2860
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P2860
Methylation reveals a niche: stem cell succession in human colon crypts.
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Methylation reveals a niche: stem cell succession in human colon crypts.
@ast
Methylation reveals a niche: stem cell succession in human colon crypts.
@en
Methylation reveals a niche: stem cell succession in human colon crypts.
@nl
type
label
Methylation reveals a niche: stem cell succession in human colon crypts.
@ast
Methylation reveals a niche: stem cell succession in human colon crypts.
@en
Methylation reveals a niche: stem cell succession in human colon crypts.
@nl
prefLabel
Methylation reveals a niche: stem cell succession in human colon crypts.
@ast
Methylation reveals a niche: stem cell succession in human colon crypts.
@en
Methylation reveals a niche: stem cell succession in human colon crypts.
@nl
P2860
P356
P1433
P1476
Methylation reveals a niche: stem cell succession in human colon crypts.
@en
P2093
Darryl Shibata
Kyoung-Mee Kim
P2860
P2888
P304
P356
10.1038/SJ.ONC.1205604
P407
P577
2002-08-01T00:00:00Z
P5875
P6179
1050800251