Identification and optimization of small-molecule agonists of the human relaxin hormone receptor RXFP1.
about
G-Protein-coupled receptors as potential drug candidates in preeclampsia: targeting the relaxin/insulin-like family peptide receptor 1 for treatment and preventionRXFP1 is Targeted by Complement C1q Tumor Necrosis Factor-Related Factor 8 in Brain CancerThe Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsML290 is a biased allosteric agonist at the relaxin receptor RXFP1.Investigation of interactions at the extracellular loops of the relaxin family peptide receptor 1 (RXFP1).International Union of Basic and Clinical Pharmacology. XCV. Recent advances in the understanding of the pharmacology and biological roles of relaxin family peptide receptors 1-4, the receptors for relaxin family peptides.Activation of Relaxin Family Receptor 1 from Different Mammalian Species by Relaxin Peptide and Small-Molecule Agonist ML290.The complex binding mode of the peptide hormone H2 relaxin to its receptor RXFP1Structural Insights into the Activation of Human Relaxin Family Peptide Receptor 1 by Small-Molecule Agonists.Allosteric and biased g protein-coupled receptor signaling regulation: potentials for new therapeutics.Targeting the relaxin hormonal pathway in prostate cancer.Synthetic non-peptide low molecular weight agonists of the relaxin receptor 1.Anti-fibrotic actions of relaxin.Relaxin-like peptides in male reproduction - a human perspective.In search of a small molecule agonist of the relaxin receptor RXFP1 for the treatment of liver fibrosis.Human Relaxin Receptor Is Fully Functional in Humanized Mice and Is Activated by Small Molecule Agonist ML290.Relaxin as a Therapeutic Target for the Cardiovascular Complications of Diabetes.Real-time examination of cAMP activity at relaxin family peptide receptors using a BRET-based biosensor
P2860
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P2860
Identification and optimization of small-molecule agonists of the human relaxin hormone receptor RXFP1.
description
2013 nî lūn-bûn
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2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Identification and optimizatio ...... elaxin hormone receptor RXFP1.
@ast
Identification and optimizatio ...... elaxin hormone receptor RXFP1.
@en
Identification and optimizatio ...... elaxin hormone receptor RXFP1.
@nl
type
label
Identification and optimizatio ...... elaxin hormone receptor RXFP1.
@ast
Identification and optimizatio ...... elaxin hormone receptor RXFP1.
@en
Identification and optimizatio ...... elaxin hormone receptor RXFP1.
@nl
prefLabel
Identification and optimizatio ...... elaxin hormone receptor RXFP1.
@ast
Identification and optimizatio ...... elaxin hormone receptor RXFP1.
@en
Identification and optimizatio ...... elaxin hormone receptor RXFP1.
@nl
P2093
P2860
P50
P356
P1476
Identification and optimizatio ...... elaxin hormone receptor RXFP1.
@en
P2093
Catherine Z Chen
Jingbo Xiao
Juan J Marugan
Marc Ferrer
Raisa E Jones
Zaohua Huang
P2860
P2888
P356
10.1038/NCOMMS2953
P407
P577
2013-01-01T00:00:00Z
P6179
1019470948