Stargazin controls the pharmacology of AMPA receptor potentiators. - Wikidata - wikimedia - TriplyDB

Stargazin controls the pharmacology of AMPA receptor potentiators.

Stargazin controls the pharmacology of AMPA receptor potentiators.

http://www.wikidata.org/entity/Q34772493

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Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins Structural and Functional Analysis of Two New Positive Allosteric Modulators of GluA2 Desensitization and Deactivation Structural analysis of the positive AMPA receptor modulators CX516 and Me-CX516 in complex with the GluA2 ligand-binding domain From synapse to nucleus: novel targets for treating depression.A charge-inverting mutation in the "linker" region of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors alters agonist binding and gating kinetics independently of allosteric modulators.Lithium acts as a potentiator of AMPAR currents in hippocampal CA1 cells by selectively increasing channel open probability.Serine racemase regulated by binding to stargazin and PSD-95: potential N-methyl-D-aspartate-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (NMDA-AMPA) glutamate neurotransmission cross-talk.Autoinactivation of the stargazin-AMPA receptor complex: subunit-dependency and independence from physical dissociation.Stargazin interaction with alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors is critically dependent on the amino acid at the narrow constriction of the ion channel.AMPA receptor potentiators: from drug design to cognitive enhancement The stoichiometry of AMPA receptors and TARPs varies by neuronal cell type.Novel toxicity of the unedited GluR2 AMPA receptor subunit dependent on surface trafficking and increased Ca2+-permeability.AMPA receptors and stargazin-like transmembrane AMPA receptor-regulatory proteins mediate hippocampal kainate neurotoxicity.Screening for AMPA receptor auxiliary subunit specific modulators.Glutamate mediates platelet activation through the AMPA receptor.α/β-Hydrolase domain-containing 6 (ABHD6) negatively regulates the surface delivery and synaptic function of AMPA receptors.The role of transmembrane AMPA receptor regulatory proteins (TARPs) in neurotransmission and receptor trafficking (Review).Regulation of AMPA receptor gating and pharmacology by TARP auxiliary subunits.Evolutionary conserved role for TARPs in the gating of glutamate receptors and tuning of synaptic function.Transmembrane AMPA receptor regulatory proteins and AMPA receptor function in the cerebellum Modulation of agonist binding to AMPA receptors by 1-(1,4-benzodioxan-6-ylcarbonyl)piperidine (CX546): differential effects across brain regions and GluA1-4/transmembrane AMPA receptor regulatory protein combinations.The Inhibitory Effect of α/β-Hydrolase Domain-Containing 6 (ABHD6) on the Surface Targeting of GluA2- and GluA3-Containing AMPA Receptors.Regulation of ionotropic glutamate receptors by their auxiliary subunits.AKAP signaling complexes in regulation of excitatory synaptic plasticity The regulation of glutamate receptor trafficking and function by TARPs and other transmembrane auxiliary subunits.Integrin regulation of cytoplasmic calcium in excitatory neurons depends upon glutamate receptors and release from intracellular stores Mapping the interaction sites between AMPA receptors and TARPs reveals a role for the receptor N-terminal domain in channel gating.TARP phosphorylation regulates synaptic AMPA receptors through lipid bilayers.Activity-mediated AMPA receptor remodeling, driven by alternative splicing in the ligand-binding domain Transmembrane AMPA receptor regulatory proteins and cornichon-2 allosterically regulate AMPA receptor antagonists and potentiators Hippocampal GluA2 and GluA4 protein but not corresponding mRNA and promoter methylation levels are modulated at retrieval in spatial learning of the rat.

P2860

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P2860

Stargazin controls the pharmacology of AMPA receptor potentiators.

http://www.wikidata.org/entity/Q34772493

description

2006 nî lūn-bûn

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2006 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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name

Stargazin controls the pharmacology of AMPA receptor potentiators.

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Stargazin controls the pharmacology of AMPA receptor potentiators.

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Stargazin controls the pharmacology of AMPA receptor potentiators.

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Stargazin controls the pharmacology of AMPA receptor potentiators.

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Stargazin controls the pharmacology of AMPA receptor potentiators.

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Stargazin controls the pharmacology of AMPA receptor potentiators.

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Stargazin controls the pharmacology of AMPA receptor potentiators.

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Stargazin controls the pharmacology of AMPA receptor potentiators.

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Stargazin controls the pharmacology of AMPA receptor potentiators.

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Proceedings of the National Academy of Sciences of the United States of America

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Stargazin controls the pharmacology of AMPA receptor potentiators.

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David S Bredt

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Keiji Wada

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Masayuki Sekiguchi

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Roger A Nicoll

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Susumu Tomita

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P2860

Facilitation of task performance and removal of the effects of sleep deprivation by an ampakine (CX717) in nonhuman primates.

Facilitation of glutamate receptors enhances memory

Functional studies and distribution define a family of transmembrane AMPA receptor regulatory proteins

A desensitization-selective potentiator of AMPA-type glutamate receptors

Mechanism of glutamate receptor desensitization

Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS

Mechanism of positive allosteric modulators acting on AMPA receptors

Stargazin reduces desensitization and slows deactivation of the AMPA-type glutamate receptors

AMPA receptor trafficking at excitatory synapses

Cloned glutamate receptors

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