Progressive myopathy and defects in the maintenance of myotendinous junctions in mice that lack talin 1 in skeletal muscle - Wikidata - wikimedia - TriplyDB

Progressive myopathy and defects in the maintenance of myotendinous junctions in mice that lack talin 1 in skeletal muscle

Progressive myopathy and defects in the maintenance of myotendinous junctions in mice that lack talin 1 in skeletal muscle

http://www.wikidata.org/entity/Q34773962

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The Structure of an Interdomain Complex That Regulates Talin Activity The structure of an integrin/talin complex reveals the basis of inside-out signal transduction.Central Region of Talin Has a Unique Fold That Binds Vinculin and Actin Mice carrying a complete deletion of the talin2 coding sequence are viable and fertile Thrombospondin-4 controls matrix assembly during development and repair of myotendinous junctions.Talins and kindlins: partners in integrin-mediated adhesion.Structural diversity in integrin/talin interactions.Studies on the morphology and spreading of human endothelial cells define key inter- and intramolecular interactions for talin1.New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2.Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload.Muscle-specific calpastatin overexpression prevents diaphragm weakness in cecal ligation puncture-induced sepsis.Talin 2 is a large and complex gene encoding multiple transcripts and protein isoforms Talin 1 and 2 are required for myoblast fusion, sarcomere assembly and the maintenance of myotendinous junctions.Vinculin and talin: focus on the myocardium Talin1 regulates integrin turnover to promote embryonic epithelial morphogenesis.Increased burden of de novo predicted deleterious variants in complex congenital diaphragmatic hernia."Importin" signaling roles for import proteins: the function of Drosophila importin-7 (DIM-7) in muscle-tendon signaling.Exome Sequencing of a Pedigree Reveals S339L Mutation in the TLN2 Gene as a Cause of Fifth Finger Camptodactyly.Focal adhesion kinase is required for IGF-I-mediated growth of skeletal muscle cells via a TSC2/mTOR/S6K1-associated pathway Deletion of the Ste20-like kinase SLK in skeletal muscle results in a progressive myopathy and muscle weakness.Connecting muscles to tendons: tendons and musculoskeletal development in flies and vertebrates Cell migration in multicellular environments.Integrin signaling in skeletal development and function.Overview of the Muscle Cytoskeleton.Endothelial cell talin1 is essential for embryonic angiogenesis.Loss of mouse cardiomyocyte talin-1 and talin-2 leads to β-1 integrin reduction, costameric instability, and dilated cardiomyopathy.Talin regulates integrin β1-dependent and -independent cell functions in ureteric bud development.Cytoskeleton and Adhesion in Myogenesis

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P2860

Progressive myopathy and defects in the maintenance of myotendinous junctions in mice that lack talin 1 in skeletal muscle

http://www.wikidata.org/entity/Q34773962

description

2008 nî lūn-bûn

@nan

2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի ապրիլին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Progressive myopathy and defec ...... ack talin 1 in skeletal muscle

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Progressive myopathy and defec ...... ack talin 1 in skeletal muscle

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Progressive myopathy and defec ...... ack talin 1 in skeletal muscle

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type

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Progressive myopathy and defec ...... ack talin 1 in skeletal muscle

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Progressive myopathy and defec ...... ack talin 1 in skeletal muscle

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Progressive myopathy and defec ...... ack talin 1 in skeletal muscle

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Progressive myopathy and defec ...... ack talin 1 in skeletal muscle

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Progressive myopathy and defec ...... ack talin 1 in skeletal muscle

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Progressive myopathy and defec ...... ack talin 1 in skeletal muscle

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Progressive myopathy and defec ...... ack talin 1 in skeletal muscle

@en

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Amanda Felder

http://www.w3.org/2001/XMLSchema#string

David Critchley

http://www.w3.org/2001/XMLSchema#string

Francesco J Conti

http://www.w3.org/2001/XMLSchema#string

Malcolm R Wood

http://www.w3.org/2001/XMLSchema#string

Martin Schwander

http://www.w3.org/2001/XMLSchema#string

Richard Lieber

http://www.w3.org/2001/XMLSchema#string

Sue Monkley

http://www.w3.org/2001/XMLSchema#string

Ulrich Müller

http://www.w3.org/2001/XMLSchema#string

P2860

Layilin, a novel talin-binding transmembrane protein homologous with C-type lectins, is localized in membrane ruffles

Integrin-linked kinase is localized to cell-matrix focal adhesions but not cell-cell adhesion sites and the focal adhesion localization of integrin-linked kinase is regulated by the PINCH-binding ANK repeats

Mutations in the integrin alpha7 gene cause congenital myopathy

Absence of integrin alpha 7 causes a novel form of muscular dystrophy

Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Integrins: versatility, modulation, and signaling in cell adhesion

Transmembrane crosstalk between the extracellular matrix--cytoskeleton crosstalk

Cytoplasmic gamma-actin is not required for skeletal muscle development but its absence leads to a progressive myopathy

Interaction of focal adhesion kinase with cytoskeletal protein talin

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2043-2053

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scholarly article

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10.1242/DEV.015818

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11

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135

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2008-04-23T00:00:00Z

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5419354

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18434420

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2562324

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