Sustained soluble guanylate cyclase stimulation offsets nitric-oxide synthase inhibition to restore acute cardiac modulation by sildenafil.
about
Phosphodiesterases and cardiac cGMP: evolving roles and controversiesPDE5A suppression of acute beta-adrenergic activation requires modulation of myocyte beta-3 signaling coupled to PKG-mediated troponin I phosphorylation.cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action.Soluble guanylate cyclase as an emerging therapeutic target in cardiopulmonary disease.Pathological cardiac hypertrophy alters intracellular targeting of phosphodiesterase type 5 from nitric oxide synthase-3 to natriuretic peptide signaling.Identification of murine phosphodiesterase 5A isoforms and their functional characterization in HL-1 cardiac cell line.Systems biology and biomechanical model of heart failureEmerging drugs for Duchenne muscular dystrophyExpression, activity, and pro-hypertrophic effects of PDE5A in cardiac myocytes.Compartmentalization of cyclic nucleotide signaling: a question of when, where, and why?Pressure-overload magnitude-dependence of the anti-hypertrophic efficacy of PDE5A inhibition.Phosphodiesterase 5 restricts NOS3/Soluble guanylate cyclase signaling to L-type Ca2+ current in cardiac myocytes.Chemotherapeutic efficacy of phosphodiesterase inhibitors in chagasic cardiomyopathy.Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics.Phosphodiesterase 5 inhibitors: are they cardioprotective?Evaluation of the therapeutic utility of phosphodiesterase 5A inhibition in the mdx mouse model of duchenne muscular dystrophy.Phosphodiesterases and cyclic GMP regulation in heart muscle.Cardiac Phosphodiesterases and Their Modulation for Treating Heart Disease.Pathways Implicated in Tadalafil Amelioration of Duchenne Muscular Dystrophy.Neuronal nitric oxide signaling regulates erection recovery after cavernous nerve injury.Effects of sildenafil treatment on patients with Peyronie's disease and erectile dysfunction.cGMP Signaling in the Cardiovascular System-The Role of Compartmentation and Its Live Cell Imaging.
P2860
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P2860
Sustained soluble guanylate cyclase stimulation offsets nitric-oxide synthase inhibition to restore acute cardiac modulation by sildenafil.
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Sustained soluble guanylate cy ...... diac modulation by sildenafil.
@ast
Sustained soluble guanylate cy ...... diac modulation by sildenafil.
@en
Sustained soluble guanylate cy ...... diac modulation by sildenafil.
@nl
type
label
Sustained soluble guanylate cy ...... diac modulation by sildenafil.
@ast
Sustained soluble guanylate cy ...... diac modulation by sildenafil.
@en
Sustained soluble guanylate cy ...... diac modulation by sildenafil.
@nl
prefLabel
Sustained soluble guanylate cy ...... diac modulation by sildenafil.
@ast
Sustained soluble guanylate cy ...... diac modulation by sildenafil.
@en
Sustained soluble guanylate cy ...... diac modulation by sildenafil.
@nl
P2093
P356
P1476
Sustained soluble guanylate cy ...... diac modulation by sildenafil.
@en
P2093
David A Kass
Eiki Takimoto
Manling Zhang
Steven Hsu
Takahiro Nagayama
P304
P356
10.1124/JPET.108.137422
P407
P577
2008-05-02T00:00:00Z