Marked accumulation of 27-hydroxycholesterol in the brains of Alzheimer's patients with the Swedish APP 670/671 mutation
about
Oxysterols in the pathogenesis of major chronic diseasesDysregulation of cholesterol balance in the brain: contribution to neurodegenerative diseasesOxidized cholesterol as the driving force behind the development of Alzheimer's diseaseGadd153 and NF-κB crosstalk regulates 27-hydroxycholesterol-induced increase in BACE1 and β-amyloid production in human neuroblastoma SH-SY5Y cells.Atherosclerosis and Alzheimer--diseases with a common cause? Inflammation, oxysterols, vasculatureCholestenoic acids regulate motor neuron survival via liver X receptors.Links between copper and cholesterol in Alzheimer's disease.Relationship between oxysterols and mild cognitive impairment in the elderly: a case-control studyDiabetic neuropathy: cellular mechanisms as therapeutic targets.The link between altered cholesterol metabolism and Alzheimer's disease.Understanding the cholesterol metabolism-perturbing effects of docosahexaenoic acid by gas chromatography-mass spectrometry targeted metabonomic profiling.The oxysterol 27-hydroxycholesterol increases oxidative stress and regulate Nrf2 signaling pathway in astrocyte cells.Oxidized LDL lipids increase β-amyloid production by SH-SY5Y cells through glutathione depletion and lipid raft formation.Hypercholesterolemia induces short-term spatial memory impairments in mice: up-regulation of acetylcholinesterase activity as an early and causal event?Can LDL cholesterol be too low? Possible risks of extremely low levels.Endoplasmic reticulum stress-induced CHOP activation mediates the down-regulation of leptin in human neuroblastoma SH-SY5Y cells treated with the oxysterol 27-hydroxycholesterol.Evidence for altered cholesterol metabolism in Huntington's disease post mortem brain tissue.Cellular hormetic response to 27-hydroxycholesterol promotes neuroprotection through AICD induction of MAST4 abundance and kinase activity.The effects of phytosterol supplementation on serum LDL-C levels and learning ability in mice fed a high-fat, high-energy diet from gestation onward.Brain Cholesterol Synthesis and Metabolism is Progressively Disturbed in the R6/1 Mouse Model of Huntington's Disease: A Targeted GC-MS/MS Sterol Analysis.Membrane lipid rafts and neurobiology: age-related changes in membrane lipids and loss of neuronal function.The relationship between cholesterol level and Alzheimer's disease-associated APP proteolysis/Aβ metabolism.
P2860
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P2860
Marked accumulation of 27-hydroxycholesterol in the brains of Alzheimer's patients with the Swedish APP 670/671 mutation
description
2011 nî lūn-bûn
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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2011 թվականի փետրվարին հրատարակված գիտական հոդված
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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name
Marked accumulation of 27-hydr ...... e Swedish APP 670/671 mutation
@ast
Marked accumulation of 27-hydr ...... e Swedish APP 670/671 mutation
@en
Marked accumulation of 27-hydr ...... e Swedish APP 670/671 mutation
@nl
type
label
Marked accumulation of 27-hydr ...... e Swedish APP 670/671 mutation
@ast
Marked accumulation of 27-hydr ...... e Swedish APP 670/671 mutation
@en
Marked accumulation of 27-hydr ...... e Swedish APP 670/671 mutation
@nl
prefLabel
Marked accumulation of 27-hydr ...... e Swedish APP 670/671 mutation
@ast
Marked accumulation of 27-hydr ...... e Swedish APP 670/671 mutation
@en
Marked accumulation of 27-hydr ...... e Swedish APP 670/671 mutation
@nl
P2093
P2860
P50
P921
P356
P1476
Marked accumulation of 27-hydr ...... e Swedish APP 670/671 mutation
@en
P2093
Amelia Marutle
Anita Lövgren-Sandblom
Hanna Pettersson
Maria Olin
Marjan Shafaati
P2860
P304
P356
10.1194/JLR.M014548
P577
2011-02-19T00:00:00Z