Pyrimidine-2,4,6-trione derivatives and their inhibition of mutant SOD1-dependent protein aggregation. Toward a treatment for amyotrophic lateral sclerosis
about
Recent progress in the discovery of small molecules for the treatment of amyotrophic lateral sclerosis (ALS)High-throughput screening for small-molecule inhibitors of plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonaseDiverse small molecule inhibitors of human apurinic/apyrimidinic endonuclease APE1 identified from a screen of a large public collectionDeuteration and fluorination of 1,3-bis(2-phenylethyl)pyrimidine-2,4,6(1H,3H,5H)-trione to improve its pharmacokinetic propertiesIdentification of small molecules that inhibit the histone chaperone Asf1 and its chromatin functionCyclohexane 1,3-diones and their inhibition of mutant SOD1-dependent protein aggregation and toxicity in PC12 cells.Direct amination of γ-halo-β-ketoesters with anilines.Tertiary Amine Pyrazolones and Their Salts as Inhibitors of Mutant Superoxide Dismutase 1-Dependent Protein Aggregation for the Treatment of Amyotrophic Lateral Sclerosis.The preclinical discovery of amyotrophic lateral sclerosis drugs.Chiral cyclohexane 1,3-diones as inhibitors of mutant SOD1-dependent protein aggregation for the treatment of ALS.Target- and mechanism-based therapeutics for neurodegenerative diseases: strength in numbers1,3-Dicyclo-hexyl-imidazolidine-2,4,5-trione.Study of mutation and misfolding of Cu-Zn SOD1 protein.
P2860
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P2860
Pyrimidine-2,4,6-trione derivatives and their inhibition of mutant SOD1-dependent protein aggregation. Toward a treatment for amyotrophic lateral sclerosis
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Pyrimidine-2,4,6-trione deriva ...... amyotrophic lateral sclerosis
@ast
Pyrimidine-2,4,6-trione deriva ...... amyotrophic lateral sclerosis
@en
Pyrimidine-2,4,6-trione deriva ...... amyotrophic lateral sclerosis
@nl
type
label
Pyrimidine-2,4,6-trione deriva ...... amyotrophic lateral sclerosis
@ast
Pyrimidine-2,4,6-trione deriva ...... amyotrophic lateral sclerosis
@en
Pyrimidine-2,4,6-trione deriva ...... amyotrophic lateral sclerosis
@nl
prefLabel
Pyrimidine-2,4,6-trione deriva ...... amyotrophic lateral sclerosis
@ast
Pyrimidine-2,4,6-trione deriva ...... amyotrophic lateral sclerosis
@en
Pyrimidine-2,4,6-trione deriva ...... amyotrophic lateral sclerosis
@nl
P2093
P2860
P356
P1476
Pyrimidine-2,4,6-trione deriva ...... amyotrophic lateral sclerosis
@en
P2093
Anthony C Arvanites
Donald R Kirsch
Guoyao Xia
Radhia Benmohamed
Richard B Silverman
Richard I Morimoto
P2860
P304
P356
10.1021/JM101549K
P407
P577
2011-03-04T00:00:00Z