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Mice as a mammalian model for research on the genetics of aging

Mice as a mammalian model for research on the genetics of aging

http://www.wikidata.org/entity/Q34780553

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Building for the future: essential infrastructure for rodent ageing studies The short-lived African turquoise killifish: an emerging experimental model for ageing Lifetime development of behavioural phenotype in the house mouse (Mus musculus)Fibrosis and renal aging Pathobiology of aging mice and GEM: background strains and experimental design The search for longevity and healthy aging genes: insights from epidemiological studies and samples of long-lived individuals Gene expression defines natural changes in mammalian lifespan Genetic variation in responses to dietary restriction--an unbiased tool for hypothesis testing Genetics of healthy aging and longevity Genetic Regulation of Female Sexual Maturation and Longevity Through Circulating IGF1 Impact of Longevity Interventions on a Validated Mouse Clinical Frailty Index Accessing Data Resources in the Mouse Phenome Database for Genetic Analysis of Murine Life Span and Health Span Inbred mouse strains reveal biomarkers that are pro-longevity, antilongevity or role switching.Genetic analysis of intracapillary glomerular lipoprotein deposits in aging mice.Genomics and successful aging: grounds for renewed optimism?Aging Research Using Mouse Models.The mouse as a model for understanding chronic diseases of aging: the histopathologic basis of aging in inbred mice.Influence of age, irradiation and humanization on NSG mouse phenotypes.Metabolic characteristics of long-lived mice.Genetic regulation of life span, metabolism, and body weight in Pohn, a new wild-derived mouse strain Models for preclinical studies in aging-related disorders: One is not for all.Changes in the expression of splicing factor transcripts and variations in alternative splicing are associated with lifespan in mice and humans.Genetic analysis of mesangial matrix expansion in aging mice and identification of Far2 as a candidate gene.Approaches to Investigating Complex Genetic Traits in a Large-Scale Inbred Mouse Aging Study.How age, sex and genotype shape the stress response.MicroRNAs miR-203-3p, miR-664-3p and miR-708-5p are associated with median strain lifespan in mice.Living long and ageing well: is epigenomics the missing link between nature and nurture?Mouse Models of Frailty: an Emerging Field.Implementation of the mouse frailty index.Genomewide Association Scan of a Mortality Associated Endophenotype for a Long and Healthy Life in the Long Life Family Study.Innate immunity in Alzheimer's disease: the relevance of animal models?Sarcopenia and piscines: the case for indeterminate-growing fish as unique genetic model organisms in aging and longevity research.Visualization of mouse spinal cord intramedullary arteries using phase- and attenuation-contrast tomographic imaging.The Pathology of Aging 129S6/SvEvTac Mice.Aging increases cell-to-cell transcriptional variability upon immune stimulation Skin immunization by microneedle patch overcomes statin-induced suppression of immune responses to influenza vaccine.Deletion of Nrip1 extends female mice longevity, increases autophagy, and delays cell senescence.Lifetime study in mice after acute low-dose ionizing radiation: a multifactorial study with special focus on cataract risk.Genetic cartography of longevity in humans and mice: Current landscape and horizons.Effect of tamoxifen on fatty degeneration and atrophy of rotator cuff muscles in chronic rotator cuff tear: An animal model study.

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P2860

Mice as a mammalian model for research on the genetics of aging

http://www.wikidata.org/entity/Q34780553

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2011 nî lūn-bûn

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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2011 թվականի հունվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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Mice as a mammalian model for research on the genetics of aging

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Mice as a mammalian model for research on the genetics of aging

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Mice as a mammalian model for research on the genetics of aging

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Mice as a mammalian model for research on the genetics of aging

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Mice as a mammalian model for research on the genetics of aging

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Beverly Paigen

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Luanne L Peters

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Rong Yuan

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P2860

Premature ageing in mice expressing defective mitochondrial DNA polymerase

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

Evolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in mice

Extending healthy life span--from yeast to humans

Calorie restriction and aging in nonhuman primates

A single IGF1 allele is a major determinant of small size in dogs

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

Suppression of aging in mice by the hormone Klotho

Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression

An Aging Interventions Testing Program: study design and interim report

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10.1093/ILAR.52.1.4

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