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Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

http://www.wikidata.org/entity/Q34780848

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Quartz-Seq: a highly reproducible and sensitive single-cell RNA sequencing method, reveals non-genetic gene-expression heterogeneity Multistable switches and their role in cellular differentiation networks Hematopoietic and mesenchymal stem cells for the treatment of chronic respiratory diseases: role of plasticity and heterogeneity Mitochondrial variability as a source of extrinsic cellular noise Nature, nurture, or chance: stochastic gene expression and its consequences The cyclic gene Hes1 contributes to diverse differentiation responses of embryonic stem cells Epigenetic principles and mechanisms underlying nervous system functions in health and disease Beyond genotype to phenotype: why the phenotype of an individual cannot always be predicted from their genome sequence and the environment that they experience The prolactin gene: a paradigm of tissue-specific gene regulation with complex temporal transcription dynamics Using variability in gene expression as a tool for studying gene regulation Interplay between gene expression noise and regulatory network architecture Imaging flow cytometry: coping with heterogeneity in biological systems The role of single-cell analyses in understanding cell lineage commitment Single-cell RNA-seq: advances and future challenges miRNA dysregulation in cancer: towards a mechanistic understanding Lineage relationship of effector and memory T cells Stochasticity and the molecular mechanisms of induced pluripotency Oscillatory protein expression dynamics endows stem cells with robust differentiation potential Bistable cell fate specification as a result of stochastic fluctuations and collective spatial cell behaviour Analysis of in vivo single cell behavior by high throughput, human-in-the-loop segmentation of three-dimensional images.Non-Darwinian dynamics in therapy-induced cancer drug resistance.Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells Mapping the environmental fitness landscape of a synthetic gene circuit Contribution of stochastic partitioning at human embryonic stem cell division to NANOG heterogeneity Calcium signals driven by single channel noise High-Throughput Single-Cell Analysis for Wound Healing Applications.Bidirectional interconversion of stem and non-stem cancer cell populations: A reassessment of theoretical models for tumor heterogeneity The reverse control of irreversible biological processes Single-cell gene expression profiling and cell state dynamics: collecting data, correlating data points and connecting the dots Epithelial cancers in the post-genomic era: should we reconsider our lifestyle?HIV promoter integration site primarily modulates transcriptional burst size rather than frequency Influence of stochastic gene expression on the cell survival rheostat after traumatic brain injury A general model for binary cell fate decision gene circuits with degeneracy: indeterminacy and switch behavior in the absence of cooperativity Modular design of artificial tissue homeostasis: robust control through synthetic cellular heterogeneity Nonheritable cellular variability accelerates the evolutionary processes of cancer Exploring the contextual sensitivity of factors that determine cell-to-cell variability in receptor-mediated apoptosis Slow protein fluctuations explain the emergence of growth phenotypes and persistence in clonal bacterial populations Expansion of multipotent stem cells from the adult human brain Survey statistics of automated segmentations applied to optical imaging of mammalian cells.Intraclonal protein expression heterogeneity in recombinant CHO cells

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P2860

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

http://www.wikidata.org/entity/Q34780848

description

2008 nî lūn-bûn

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2008 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2008 թվականի մայիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

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Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

@en

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

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type

label

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

@ast

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

@en

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

@nl

prefLabel

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

@ast

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

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Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

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Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

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Hannah H Chang

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Martin Hemberg

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Sui Huang

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P2860

Significance analysis of microarrays applied to the ionizing radiation response

Multistable and multistep dynamics in neutrophil differentiation.

Stochastic gene expression in a single cell

Gene regulation at the single-cell level

Control of stochasticity in eukaryotic gene expression

Stochasticity in gene expression: from theories to phenotypes

Noise in eukaryotic gene expression

Mouse hematopoietic stem-cell antigen Sca-1 is a member of the Ly-6 antigen family

Distinct domains of the GATA-1 cofactor FOG-1 differentially influence erythroid versus megakaryocytic maturation.

Noise propagation in gene networks.

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10.1038/NATURE06965

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7194

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453

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Mauricio Barahona

Donald E. Ingber

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2008-05-01T00:00:00Z

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5351960

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1031252068

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