DNA damage strength modulates a bimodal switch of p53 dynamics for cell-fate control
about
Quantifying intrinsic and extrinsic control of single-cell fates in cancer and stem/progenitor cell pedigrees with competing risks analysisExcitability in the p53 network mediates robust signaling with tunable activation thresholds in single cellsDynamics of posttranslational modifications of p53.Melatonin and its metabolites protect human melanocytes against UVB-induced damage: Involvement of NRF2-mediated pathwaysThe p53 response in single cells is linearly correlated to the number of DNA breaks without a distinct threshold.Integrated Stochastic Model of DNA Damage Repair by Non-homologous End Joining and p53/p21-Mediated Early Senescence SignallingBifurcation in Cell Cycle Dynamics Regulated by p53MiR-192-Mediated Positive Feedback Loop Controls the Robustness of Stress-Induced p53 Oscillations in Breast Cancer CellsHow time delay and network design shape response patterns in biochemical negative feedback systemsNucleocytoplasmic Translocation of UBXN2A Is Required for Apoptosis during DNA Damage Stresses in Colon Cancer Cells.Influenza infection induces host DNA damage and dynamic DNA damage responses during tissue regeneration.Pneumococcal Pneumolysin Induces DNA Damage and Cell Cycle ArrestModeling amplified p53 responses under DNA-PK inhibition in DNA damage responseNovel non-calcemic secosteroids that are produced by human epidermal keratinocytes protect against solar radiation.On the role of classical and novel forms of vitamin D in melanoma progression and management.p53 oligomerization status modulates cell fate decisions between growth, arrest and apoptosis.Hyperactivation of ATM upon DNA-PKcs inhibition modulates p53 dynamics and cell fate in response to DNA damage.Unraveling cellular pathways contributing to drug-induced liver injury by dynamical modeling.Melatonin and its metabolites ameliorate ultraviolet B-induced damage in human epidermal keratinocytes.Post-slippage multinucleation renders cytotoxic variation in anti-mitotic drugs that target the microtubules or mitotic spindle.Dying to protect: cell death and the control of T-cell homeostasis.Effect of HPV E6/E7 siRNA with Chemotherapeutic Agents on the Regulation of TP53/E2F Dynamic Behavior for Cell Fate DecisionsCorrelation between oncogenic mutations and parameter sensitivity of the apoptosis pathway modelMicroRNA-16 feedback loop with p53 and Wip1 can regulate cell fate determination between apoptosis and senescence in DNA damage response.MicroRNA-124 functions as a tumor suppressor and indicates prognosis in human osteosarcoma.p53 dynamics orchestrates with binding affinity to target genes for cell fate decision.Understanding non-linear effects from Hill-type dynamics with application to decoding of p53 signaling.p53 dynamics in response to DNA damage vary across cell lines and are shaped by efficiency of DNA repair and activity of the kinase ATM.A plausible model for bimodal p53 switch in DNA damage response.Recent progress and open challenges in modeling p53 dynamics in single cells.
P2860
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P2860
DNA damage strength modulates a bimodal switch of p53 dynamics for cell-fate control
description
2013 nî lūn-bûn
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2013 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունիսին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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name
DNA damage strength modulates a bimodal switch of p53 dynamics for cell-fate control
@ast
DNA damage strength modulates a bimodal switch of p53 dynamics for cell-fate control
@en
DNA damage strength modulates a bimodal switch of p53 dynamics for cell-fate control
@nl
type
label
DNA damage strength modulates a bimodal switch of p53 dynamics for cell-fate control
@ast
DNA damage strength modulates a bimodal switch of p53 dynamics for cell-fate control
@en
DNA damage strength modulates a bimodal switch of p53 dynamics for cell-fate control
@nl
prefLabel
DNA damage strength modulates a bimodal switch of p53 dynamics for cell-fate control
@ast
DNA damage strength modulates a bimodal switch of p53 dynamics for cell-fate control
@en
DNA damage strength modulates a bimodal switch of p53 dynamics for cell-fate control
@nl
P2093
P2860
P356
P1433
P1476
DNA damage strength modulates a bimodal switch of p53 dynamics for cell-fate control
@en
P2093
P2860
P2888
P356
10.1186/1741-7007-11-73
P50
P577
2013-06-21T00:00:00Z
P5875
P6179
1007215389