Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice - Wikidata - wikimedia - TriplyDB

Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice

Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice

http://www.wikidata.org/entity/Q34783878

about

Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis The transcription factor ATOH8 is regulated by erythropoietic activity and regulates HAMP transcription and cellular pSMAD1,5,8 levels Hepcidin: regulation of the master iron regulator The hepcidin-ferroportin system as a therapeutic target in anemias and iron overload disorders Hepcidin and iron homeostasis New insights into iron regulation and erythropoiesis Mechanisms of mammalian iron homeostasis Bmp6 expression in murine liver non parenchymal cells: a mechanism to control their high iron exporter activity and protect hepatocytes from iron overload?Outward- and inward-facing structures of a putative bacterial transition-metal transporter with homology to ferroportin.Effect of Erythropoietin, Iron Deficiency and Iron Overload on Liver Matriptase-2 (TMPRSS6) Protein Content in Mice and Rats Iron-dependent regulation of hepcidin in Hjv-/- mice: evidence that hemojuvelin is dispensable for sensing body iron levels Hepcidin and iron regulation, 10 years later.Iron regulation by hepcidin Suppression of iron-regulatory hepcidin by vitamin D Hepcidin and sports anemia BMP type II receptors have redundant roles in the regulation of hepatic hepcidin gene expression and iron metabolism A nanoparticulate ferritin-core mimetic is well taken up by HuTu 80 duodenal cells and its absorption in mice is regulated by body iron.Iron and inflammation - the gut reaction.Increased iron loading induces Bmp6 expression in the non-parenchymal cells of the liver independent of the BMP-signaling pathway.Low hepcidin levels in severely anemic malawian children with high incidence of infectious diseases and bone marrow iron deficiency Mouse models of anemia of cancer The second transferrin receptor regulates red blood cell production in mice.HJV and HFE Play Distinct Roles in Regulating Hepcidin.Chuvash polycythemia VHLR200W mutation is associated with down-regulation of hepcidin expression.Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload Hereditary hemochromatosis and transferrin receptor 2 Inhibition of hepcidin transcription by growth factors.Hepatic hypoxia-inducible factor-2 down-regulates hepcidin expression in mice through an erythropoietin-mediated increase in erythropoiesis Ferritin upregulates hepatic expression of bone morphogenetic protein 6 and hepcidin in mice.Transgenic HFE-dependent induction of hepcidin in mice does not require transferrin receptor-2.Intravenous Iron Carboxymaltose as a Potential Therapeutic in Anemia of Inflammation.Modelling Systemic Iron Regulation during Dietary Iron Overload and Acute Inflammation: Role of Hepcidin-Independent Mechanisms.Isocitrate treatment of acute anemia of inflammation in a mouse model.Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis.Erythropoietic drive is the strongest predictor of hepcidin level in adults with sickle cell disease Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia Unraveling mechanisms regulating systemic iron homeostasis.Effects of Testosterone on Erythropoiesis in a Female Mouse Model of Anemia of Inflammation Transforming Growth Factor β1 (TGF-β1) Activates Hepcidin mRNA Expression in Hepatocytes The liver: conductor of systemic iron balance.

P2860

Q21129271-4DC9E24F-6129-4A12-9BCD-0A6AA95FD6B7 Q24339599-1A7EDD96-E569-4BCA-B973-F9F58563B631 Q26800198-FC76EB0C-320F-4F2D-98CB-1870BF6753A9 Q26823465-9548E1D8-C67F-4B88-AF4D-E9620AC4B83D Q27002595-9F73F808-A3EB-48DC-8071-39DA94548B06 Q27009305-DB22219C-AE25-43C3-B93E-0F847A00042F Q27010510-5DF00A08-1E6B-46A1-8D91-1BDC41B73DA3 Q27310179-D9C6D490-227D-4BD7-B927-2BC53AF013AA Q27321351-F6F42347-CE5D-4BF7-9E06-9B189D1273FF Q27323133-2D3ACEF3-28D9-4FF0-9F92-6EC957E9A0DD Q27333705-EFE51A14-D461-4A7D-8C29-DE8216018FA0 Q27690828-75BFE993-1120-4D44-AB13-EAC19877EBE2 Q28291718-FF59BEB5-676F-4A10-B1BC-68CFE350C2B8 Q28301486-6E4FC45C-A2D5-4C7B-81B1-4C8F16DBBDF0 Q33559763-C322636F-87CC-4081-AECC-54B4C0CE7475 Q34293026-879025EE-712C-4405-8815-2C2AB47BAB7D Q34502262-E3F0FFE2-7561-4E96-89F0-700A5C29BA75 Q34548797-478A8BF5-D944-4F96-AAF8-F6C97C047DB2 Q34658504-8055B0DE-6286-4FAC-8CFE-B2546B035D95 Q35067289-7C3B5B84-B8F5-4730-9C09-D527FA1D48F6 Q35135015-2AD61FFE-B42D-4FD4-B517-82C395F9E266 Q35446281-01F1D1D9-830B-45D3-BADA-E47D2030889D Q35540918-87148FDC-4982-4F0D-86E2-118630031365 Q35553601-EC7B92FD-1B87-40E3-8D38-0FE29646D950 Q35578602-6E878D06-E734-4D8D-A376-E4AFA86C282D Q35603164-F343183F-E236-481F-98C3-203E475C8A92 Q35996119-4822FC7E-8B84-411F-B51E-A0D731BAE7F0 Q36006369-B3F675F5-818C-4424-918B-904E0EA51C3C Q36041975-97F4F8B8-60C3-4F7B-A030-7CE67CCFAFF4 Q36067487-7408879F-092D-4122-A54D-4BD0BF3B319B Q36073896-8C661C91-BE92-46C1-BA94-751D2D6688EA Q36244408-4A0017DE-54EB-4386-BAA6-D5FBADCEF1B0 Q36320635-1806134A-ED37-42B1-9C52-7F8ADA7A9D40 Q36370876-1E291235-03AF-4502-9E3D-53A366C2094D Q36581603-310EC3A1-2DF5-492D-8DB1-298F2C2D5FA0 Q36745518-C7CE6ED9-68E9-4F26-9B73-D5C160F88720 Q36828496-E2B9F2DF-24AD-443D-8258-9CF536B42A63 Q37057480-71A5F38E-20D9-44D9-B9D0-9B3E66486CCA Q37065891-7E139B9D-BEDF-49A8-A9A2-570FB984F1AB Q37464105-94AEC2FE-BB09-4447-8059-5C0A462D3B3F

P2860

Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice

http://www.wikidata.org/entity/Q34783878

description

2011 nî lūn-bûn

@nan

2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Evidence for distinct pathways ...... d chronic iron loading in mice

@ast

Evidence for distinct pathways ...... d chronic iron loading in mice

@en

Evidence for distinct pathways ...... d chronic iron loading in mice

@nl

type

label

Evidence for distinct pathways ...... d chronic iron loading in mice

@ast

Evidence for distinct pathways ...... d chronic iron loading in mice

@en

Evidence for distinct pathways ...... d chronic iron loading in mice

@nl

prefLabel

Evidence for distinct pathways ...... d chronic iron loading in mice

@ast

Evidence for distinct pathways ...... d chronic iron loading in mice

@en

Evidence for distinct pathways ...... d chronic iron loading in mice

@nl

P1433

Q34783878-341BCFB2-5554-49AE-A927-17C842AED703

P1476

Q34783878-32E8DCAD-8EF8-4B49-B96E-FC262D940D16

P2093

Q34783878-0C8E0DE1-B971-4323-B0C8-36556E3E8F46

Q34783878-2E5011D1-FEB1-42CA-A1DD-4BC731ADE6C2

Q34783878-3DE36562-4C94-46B5-8C07-D76758A3109D

Q34783878-71A1637C-5E9F-4C95-9E4F-BCF635E288D4

Q34783878-9468DCB3-24F4-42EC-944F-A47BA1AC145B

Q34783878-B9FD7D61-FABF-4940-91FE-18379C3AB9CB

Q34783878-BB7A46C0-DA24-4AE9-A350-EDE6853560BF

P2860

Q34783878-10A8A447-830D-4BB1-B55B-EADF38EDBABC

Q34783878-13AD0737-0B79-4ADC-BF67-9317A4B8DC65

Q34783878-18492370-48DE-4510-94E0-F6C87DFA55F8

Q34783878-1FA3C8E5-2E0F-4134-AFAA-449B275C2AAB

Q34783878-41983F86-140F-4DA8-B470-CE0A37267266

Q34783878-4385955B-AE38-4402-BC42-FD4BCB4BB363

Q34783878-44577425-F510-4FED-9988-EA814CF1EEEE

Q34783878-56C485C7-D2B2-4DCC-9015-7F8CC77376AC

Q34783878-58DF8803-9584-41C9-939B-F5A88D8088C1

Q34783878-6A637CDA-5A39-492F-A328-6536CF989685

P304

Q34783878-9A715DEB-80A3-467F-93CE-9C60ADB45FB4

P31

Q34783878-2F9341AF-B71A-4ABF-88C1-4430A058B6B0

P356

Q34783878-273C4013-38BC-451D-BB12-C8B370A6A019

P407

Q34783878-12424900-04E6-40AD-B01A-1E40BA31FBED

P433

Q34783878-90BBB12E-75B6-43A2-AFE6-7D3AA6149742

P478

Q34783878-D311CA01-35CF-40EF-A51C-BB83B5874625

P50

Q34783878-76666570-61F5-4177-960C-A523F41C4768

Q34783878-C0AD1185-0133-48CC-A157-E34C8053F104

P577

Q34783878-0AB1B775-0A4C-4BB4-A187-44A7C5364C9F

P5875

Q34783878-DBA6000C-1CDA-4509-9FF0-56595A82A223

P698

Q34783878-B5BDBAEE-C52D-4D62-8A23-D147CDFB8084

P932

Q34783878-CED46D2C-D654-42CA-8961-671707B47703

P356

P1433

P1476

Evidence for distinct pathways ...... d chronic iron loading in mice

@en

P2093

Elizabeta Nemeth

http://www.w3.org/2001/XMLSchema#string

Emilio Ramos

http://www.w3.org/2001/XMLSchema#string

Marie-Paule Roth

http://www.w3.org/2001/XMLSchema#string

Michael Hansen

http://www.w3.org/2001/XMLSchema#string

Richard Rodriguez

http://www.w3.org/2001/XMLSchema#string

Victoria Gabayan

http://www.w3.org/2001/XMLSchema#string

Yelena Ginzburg

http://www.w3.org/2001/XMLSchema#string

P2860

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload

IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin

The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin

Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

Mechanisms of iron accumulation in hereditary hemochromatosis.

Transferrin is a major determinant of hepcidin expression in hypotransferrinemic mice

Hfe acts in hepatocytes to prevent hemochromatosis.

P304

1333-1341

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1002/HEP.24178

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

53

http://www.w3.org/2001/XMLSchema#string

P50

P577

2011-04-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51039248

http://www.w3.org/2001/XMLSchema#string

P698

21480335

http://www.w3.org/2001/XMLSchema#string

P932

3074982

http://www.w3.org/2001/XMLSchema#string