Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression
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Mitochondria in the diabetic heartCardiovascular Action of Insulin in Health and Disease: Endothelial L-Arginine Transport and Cardiac Voltage-Dependent Potassium ChannelsNew Molecular Insights of Insulin in Diabetic CardiomyopathyDiabetes and cardiovascular disease: Epidemiology, biological mechanisms, treatment recommendations and future researchInsulin resistance protects the heart from fuel overload in dysregulated metabolic statesThe mitochondria in diabetic heart failure: from pathogenesis to therapeutic promiseCardiac dysfunction and oxidative stress in the metabolic syndrome: an update on antioxidant therapiesMolecular basis of physiological heart growth: fundamental concepts and new playersMechanistic target of rapamycin (Mtor) is essential for murine embryonic heart development and growthA Drosophila model of high sugar diet-induced cardiomyopathyGlucose Transporters in Cardiac Metabolism and HypertrophyDiabetic Cardiomyopathy: Does the Type of Diabetes Matter?The alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouseDistinct transcriptional regulation of long-chain acyl-CoA synthetase isoforms and cytosolic thioesterase 1 in the rodent heart by fatty acids and insulinTissue-specific pyruvate dehydrogenase complex deficiency causes cardiac hypertrophy and sudden death of weaned male miceInsulin Signaling and Heart Failure.Effects of stretch and shortening on gene expression in intact myocardium.PTG gene deletion causes impaired glycogen synthesis and developmental insulin resistanceAbnormal myocardial insulin signalling in type 2 diabetes and left-ventricular dysfunction.GLUT1 deficiency in cardiomyocytes does not accelerate the transition from compensated hypertrophy to heart failure.Acute inhibition of fatty acid import inhibits GLUT4 transcription in adipose tissue, but not skeletal or cardiac muscle tissue, partly through liver X receptor (LXR) signaling.Co-activation of nuclear factor-κB and myocardin/serum response factor conveys the hypertrophy signal of high insulin levels in cardiac myoblasts.Insulin inhibits cardiac contractility by inducing a Gi-biased β2-adrenergic signaling in hearts.The FoxO family in cardiac function and dysfunction.Diabetic cardiomyopathy, causes and effects.Cardiac remodeling in obesity.Insulin receptor substrates are essential for the bioenergetic and hypertrophic response of the heart to exercise training.Diabetic cardiomyopathy: recent evidence from mouse models of type 1 and type 2 diabetes.Activation of mitochondrial energy metabolism protects against cardiac failure.Myocardial insulin resistance induced by high fat feeding in heart failure is associated with preserved contractile function.Alpha1-adrenergic receptors prevent a maladaptive cardiac response to pressure overload.Knockout of insulin receptors in cardiomyocytes attenuates coronary arterial dysfunction induced by pressure overloadCaptopril normalizes insulin signaling and insulin-regulated substrate metabolism in obese (ob/ob) mouse hearts.Glucose phosphorylation is required for insulin-dependent mTOR signalling in the heart.Insulin/IGF-1 signaling, including class II/III PI3Ks, β-arrestin and SGK-1, is required in C. elegans to maintain pharyngeal muscle performance during starvation.IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development.Role of Endothelial Cells in Myocardial Ischemia-Reperfusion Injury.Akt activation induces hypertrophy without contractile phenotypic maturation in airway smooth muscleHigh-sugar diets increase cardiac dysfunction and mortality in hypertension compared to low-carbohydrate or high-starch diets.PGC-1β deficiency accelerates the transition to heart failure in pressure overload hypertrophy.
P2860
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P2860
Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression
description
2002 nî lūn-bûn
@nan
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մարտին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Insulin signaling coordinately ...... ile protein isoform expression
@ast
Insulin signaling coordinately ...... ile protein isoform expression
@en
Insulin signaling coordinately ...... ile protein isoform expression
@nl
type
label
Insulin signaling coordinately ...... ile protein isoform expression
@ast
Insulin signaling coordinately ...... ile protein isoform expression
@en
Insulin signaling coordinately ...... ile protein isoform expression
@nl
prefLabel
Insulin signaling coordinately ...... ile protein isoform expression
@ast
Insulin signaling coordinately ...... ile protein isoform expression
@en
Insulin signaling coordinately ...... ile protein isoform expression
@nl
P2093
P2860
P356
P1476
Insulin signaling coordinately ...... ile protein isoform expression
@en
P2093
Christophe Graveleau
Darrell D Belke
David Severson
Donald A McClain
Dongfang Zhang
E Dale Abel
Heinrich Taegtmeyer
Martin E Young
Martin J Tuttle
P2860
P304
P356
10.1172/JCI0213946
P407
P577
2002-03-01T00:00:00Z