The prostaglandin receptor EP4 suppresses colitis, mucosal damage and CD4 cell activation in the gut
about
Interaction of eosinophils with endothelial cells is modulated by prostaglandin EP4 receptorsProstaglandin E receptor type 4-associated protein interacts directly with NF-kappaB1 and attenuates macrophage activationDecreased susceptibility to renovascular hypertension in mice lacking the prostaglandin I2 receptor IPCastor oil induces laxation and uterus contraction via ricinoleic acid activating prostaglandin EP3 receptorsInterleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host diseaseHelminths and harmonyE-type prostanoid receptor 4 (EP4) in disease and therapyIntegrative approach to analyze biodiversity and anti-inflammatory bioactivity of Wedelia medicinal plantsImmune antibodies and helminth products drive CXCR2-dependent macrophage-myofibroblast crosstalk to promote intestinal repairThe Prostaglandin E2 Receptor EP4 Regulates Obesity-Related Inflammation and Insulin SensitivityNovel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4Inflammatory bowel diseaseInflammatory bowel diseaseRhoA/Rho kinase signaling in the cumulus mediates extracellular matrix assembly.Prostaglandin E2 is required for ultraviolet B-induced skin inflammation via EP2 and EP4 receptors.Prostanoid receptor antagonists: development strategies and therapeutic applicationsThe role of prostaglandin E2 (PGE 2) in toll-like receptor 4 (TLR4)-mediated colitis-associated neoplasiaIn vivo imaging reveals PKA regulation of ERK activity during neutrophil recruitment to inflamed intestines.Emerging roles of PGE2 receptors in models of neurological disease.Genetic variation in prostaglandin E2 synthesis and signaling, prostaglandin dehydrogenase, and the risk of colorectal adenoma.EP4 inhibition attenuates the development of diabetic and non-diabetic experimental kidney disease.Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis.Antagonizing arachidonic acid-derived eicosanoids reduces inflammatory Th17 and Th1 cell-mediated inflammation and colitis severity.Microsomal prostaglandin E synthase-1 contributes to ischaemic excitotoxicity through prostaglandin E2 EP3 receptors.Emerging roles of prostanoids in T cell-mediated immunity.Crucial role of macrophage selenoproteins in experimental colitis.Insights from advances in research of chemically induced experimental models of human inflammatory bowel disease.Inhibition of EP4 signaling attenuates aortic aneurysm formationRole of Janus kinase 3 in mucosal differentiation and predisposition to colitisInterleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9-driven antiinflammatory cytokine production.The opioid peptide nociceptin/orphanin FQ mediates prostaglandin E2-induced allodynia, tactile pain associated with nerve injury.PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sitesParturition and recruitment of macrophages in cervix of mice lacking the prostaglandin F receptorCox-2 deletion in myeloid and endothelial cells, but not in epithelial cells, exacerbates murine colitis.Selective activation of the prostaglandin E2 circuit in chronic injury-induced pathologic angiogenesisLymphocytic colitis is associated with increased pro-inflammatory cytokine profile and up regulation of prostaglandin receptor EP4.Crucial role for CD69 in the pathogenesis of dextran sulphate sodium-induced colitis.Prostaglandin E2-prostaglandin E receptor subtype 4 (EP4) signaling mediates UV irradiation-induced systemic immunosuppression.Prostaglandin E2-EP3 axis in fine-tuning excessive skin inflammation by restricting dendritic cell functions.Impact of disrupting adenosine A₃ receptors (A₃⁻/⁻ AR) on colonic motility or progression of colitis in the mouse.
P2860
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P2860
The prostaglandin receptor EP4 suppresses colitis, mucosal damage and CD4 cell activation in the gut
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The prostaglandin receptor EP4 ...... CD4 cell activation in the gut
@ast
The prostaglandin receptor EP4 ...... CD4 cell activation in the gut
@en
The prostaglandin receptor EP4 ...... CD4 cell activation in the gut
@nl
type
label
The prostaglandin receptor EP4 ...... CD4 cell activation in the gut
@ast
The prostaglandin receptor EP4 ...... CD4 cell activation in the gut
@en
The prostaglandin receptor EP4 ...... CD4 cell activation in the gut
@nl
prefLabel
The prostaglandin receptor EP4 ...... CD4 cell activation in the gut
@ast
The prostaglandin receptor EP4 ...... CD4 cell activation in the gut
@en
The prostaglandin receptor EP4 ...... CD4 cell activation in the gut
@nl
P2093
P2860
P356
P1476
The prostaglandin receptor EP4 ...... CD4 cell activation in the gut
@en
P2093
Atsushi Ichikawa
Kazuhito Tsuboi
Kenji Kabashima
Miyako Nagamachi
Shuh Narumiya
Takahiko Murata
Takuya Kobayashi
Tomomi Saji
Toshiyuki Matsuoka
P2860
P304
P356
10.1172/JCI0214459
P407
P577
2002-04-01T00:00:00Z