Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair. - Wikidata - wikimedia - TriplyDB

Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair.

Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair.

http://www.wikidata.org/entity/Q34792085

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Expression of alternatively spliced isoforms of human Sp7 in osteoblast-like cells Non-steroidal anti-inflammatory drugs (NSAIDs) for axial spondyloarthritis (ankylosing spondylitis and non-radiographic axial spondyloarthritis)Non-steroidal anti-inflammatory drugs (NSAIDs) for axial spondyloarthritis (ankylosing spondylitis and non-radiographic axial spondyloarthritis)TIEG1 null mouse-derived osteoblasts are defective in mineralization and in support of osteoclast differentiation in vitro Cox-2: Where are we in 2003? - The role of cyclooxygenase-2 in bone repair Lead exposure inhibits fracture healing and is associated with increased chondrogenesis, delay in cartilage mineralization, and a decrease in osteoprogenitor frequency.The Essentiality of Arachidonic Acid in Infant Development NSAID therapy effects on healing of bone, tendon, and the enthesis Current insights on the regenerative potential of the periosteum: molecular, cellular, and endogenous engineering approaches Phospholipases of mineralization competent cells and matrix vesicles: roles in physiological and pathological mineralizations P2X7 receptors on osteoblasts couple to production of lysophosphatidic acid: a signaling axis promoting osteogenesis Angiogenesis in bone regeneration.Primary cilia-mediated mechanotransduction in human mesenchymal stem cells.Low-level laser therapy modulates cyclo-oxygenase-2 expression during bone repair in rats.Low-level laser therapy improves bone repair in rats treated with anti-inflammatory drugs.Fracture healing and lipid mediators.In vivo microfocal computed tomography and micro-magnetic resonance imaging evaluation of antiresorptive and antiinflammatory drugs as preventive treatments of osteoarthritis in the rat.Efficacy of colistin-impregnated beads to prevent multidrug-resistant A. baumannii implant-associated osteomyelitis.Celecoxib does not appear to affect prosthesis fixation in total knee replacement: A randomized study using radiostereometry in 50 patients.Effect of Non-Steroidal Anti-Inflammatory Drugs on Bone Healing Biosilicate® and low-level laser therapy improve bone repair in osteoporotic rats.Delayed fracture healing and increased callus adiposity in a C57BL/6J murine model of obesity-associated type 2 diabetes mellitus.Compensatory cellular reactions to nonsteroidal anti-inflammatory drugs on osteogenic differentiation in canine bone marrow-derived mesenchymal stem cells.Prostaglandins in bone: bad cop, good cop?The spatiotemporal role of COX-2 in osteogenic and chondrogenic differentiation of periosteum-derived mesenchymal progenitors in fracture repair.Electrospun fibers as a scaffolding platform for bone tissue repair.Embryonic expression of cyclooxygenase-2 causes malformations in axial skeleton.Aging periosteal progenitor cells have reduced regenerative responsiveness to bone injury and to the anabolic actions of PTH 1-34 treatment.Role of donor and host cells in muscle-derived stem cell-mediated bone repair: differentiation vs. paracrine effects.Hypoxia regulates PGE(2) release and EP1 receptor expression in osteoblastic cells.A novel role for interferon regulatory factor 1 (IRF1) in regulation of bone metabolism The effect of risedronate on osteogenic lineage is mediated by cyclooxygenase-2 gene upregulation Osteocyte expression of caspase-3, COX-2, IL-6 and sclerostin are spatially and temporally associated following stress fracture initiation.Activation of NF-κB/p65 facilitates early chondrogenic differentiation during endochondral ossification Microarray Analysis of Gene Expression Reveals that Cyclo-oxygenase-2 Gene Therapy Up-regulates Hematopoiesis and Down-regulates Inflammation During Endochondral Bone Fracture Healing.Modulation of the inflammatory response for enhanced bone tissue regeneration Local simvastatin effects on mandibular bone growth and inflammation Remodeling of cortical bone allografts mediated by adherent rAAV-RANKL and VEGF gene therapy.Activation of the Hh pathway in periosteum-derived mesenchymal stem cells induces bone formation in vivo: implication for postnatal bone repair.Accelerated calvarial healing in mice lacking Toll-like receptor 4.

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Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair.

http://www.wikidata.org/entity/Q34792085

description

2002 nî lūn-bûn

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Cyclooxygenase-2 regulates mes ...... cally involved in bone repair.

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Cyclooxygenase-2 regulates mes ...... cally involved in bone repair.

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Cyclooxygenase-2 regulates mes ...... cally involved in bone repair.

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Journal of Clinical Investigation

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Cyclooxygenase-2 regulates mes ...... cally involved in bone repair.

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P2093

Donald A Young

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Edward M Schwarz

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J Edward Puzas

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Randy N Rosier

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Regis J O'Keefe

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Xinping Zhang

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P2860

The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation

Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

Prostaglandins and bone: physiology and pathophysiology.

Growth factor regulation of fracture repair.

Mesenchymal stem cells in bone development, bone repair, and skeletal regeneration therapy.

Regulatory mechanisms in the pathways of cartilage and bone formation.

Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts

Prostaglandin G/H synthase-2 is required for maximal formation of osteoclast-like cells in culture.

Physiologic and pathologic roles of prostaglandins and other eicosanoids in bone metabolism.

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10.1172/JCI0215681

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11

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