Adhesion and Invasion of Breast and Oesophageal Cancer Cells Are Impeded by Anti-LRP/LR-Specific Antibody IgG1-iS18.
about
The 37kDa/67kDa laminin receptor acts as a receptor for Aβ42 internalization.Down-regulation of Filamin A interacting protein 1-like Is associated with promoter methylation and an invasive phenotype in breast, colon, lung and pancreatic cancers [corrected]Anti-LRP/LR specific antibody IgG1-iS18 impedes adhesion and invasion of liver cancer cells.High resolution imaging study of interactions between the 37 kDa/67 kDa laminin receptor and APP, beta-secretase and gamma-secretase in Alzheimer's disease.Knockdown of LRP/LR Induces Apoptosis in Breast and Oesophageal Cancer CellsKnock-Down of the 37kDa/67kDa Laminin Receptor LRP/LR Impedes Telomerase ActivityAnti-LRP/LR-specific antibody IgG1-iS18 impedes adhesion and invasion of pancreatic cancer and neuroblastoma cellsDiscovery of new small molecules inhibiting 67 kDa laminin receptor interaction with laminin and cancer cell invasionAnti-LRP/LR specific antibodies and shRNAs impede amyloid beta shedding in Alzheimer's disease.Anti-LRP/LR specific antibody IgG1-iS18 and knock-down of LRP/LR by shRNAs rescue cells from Aβ42 induced cytotoxicityAnti-LRP/LR specific antibody IgG1-iS18 significantly impedes adhesion and invasion in early and late stage colorectal carcinoma cells.Novel patented therapeutic approaches targeting the 37/67 kDa laminin receptor for treatment of cancer and Alzheimer's disease.LRP/LR Antibody Mediated Rescuing of Amyloid-β-Induced Cytotoxicity is Dependent on PrPc in Alzheimer's Disease.The 37/67 kDa laminin receptor (LR) inhibitor, NSC47924, affects 37/67 kDa LR cell surface localization and interaction with the cellular prion protein.37 kDa LRP::FLAG enhances telomerase activity and reduces senescent markers in vitro.Knock-down of LRP/LR promotes apoptosis in early and late stage colorectal carcinoma cells via caspase activation.
P2860
Q33840258-4E4B6016-B13B-43B6-B651-971DF3C5EBDDQ35067854-0FB21DED-FCCA-40AB-8D32-646FDB1CFF51Q35163314-3F4EF91F-AD74-45BA-AF32-EC2E82FA8416Q35196471-1BA1BBFF-3644-4EC4-AD8F-5C98C31C1A41Q35795325-13AD2199-BE4D-400F-90D1-5E3E5C65B078Q35834441-133E1C94-746A-4688-8539-F79C009571A1Q36203476-812B82BF-F993-402C-94E3-12D9C2A55C61Q36228519-722244BA-B000-40A8-91B0-987042C0DA2DQ37182132-BB9D6700-968F-41A9-8299-1B5705D92C07Q37182136-2F5D2894-1112-462A-A459-A41AAC46902BQ37370538-FBA94D83-D2BC-481C-BF76-E3A664F4C6D9Q38369288-7D66F0AA-99FC-4DCE-9E3C-5DE1AD21FFBEQ38826444-E359AA21-208E-4E43-B4E8-0F1C7D079EC8Q39856446-AEEED919-AC1F-4B21-AF60-CC877270FECEQ46187627-FD9A3BB4-707D-4AA8-AD2E-55E4392F0BB9Q54956797-6B20DA86-A87A-41F7-BAAF-03E0645344ED
P2860
Adhesion and Invasion of Breast and Oesophageal Cancer Cells Are Impeded by Anti-LRP/LR-Specific Antibody IgG1-iS18.
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Adhesion and Invasion of Breas ...... R-Specific Antibody IgG1-iS18.
@ast
Adhesion and Invasion of Breas ...... R-Specific Antibody IgG1-iS18.
@en
Adhesion and Invasion of Breas ...... R-Specific Antibody IgG1-iS18.
@nl
type
label
Adhesion and Invasion of Breas ...... R-Specific Antibody IgG1-iS18.
@ast
Adhesion and Invasion of Breas ...... R-Specific Antibody IgG1-iS18.
@en
Adhesion and Invasion of Breas ...... R-Specific Antibody IgG1-iS18.
@nl
prefLabel
Adhesion and Invasion of Breas ...... R-Specific Antibody IgG1-iS18.
@ast
Adhesion and Invasion of Breas ...... R-Specific Antibody IgG1-iS18.
@en
Adhesion and Invasion of Breas ...... R-Specific Antibody IgG1-iS18.
@nl
P2093
P2860
P1433
P1476
Adhesion and Invasion of Breas ...... R-Specific Antibody IgG1-iS18.
@en
P2093
Melvyn Little
Robin B Veale
Stefan F T Weiss
Stefan Knackmuss
Thandokuhle Khumalo
Uwe Reusch
P2860
P304
P356
10.1371/JOURNAL.PONE.0066297
P407
P577
2013-06-18T00:00:00Z