Longitudinal Analysis of CCR5 and CXCR4 Usage in a Cohort of Antiretroviral Therapy-Naïve Subjects with Progressive HIV-1 Subtype C Infection.

Longitudinal Analysis of CCR5 and CXCR4 Usage in a Cohort of Antiretroviral Therapy-Naïve Subjects with Progressive HIV-1 Subtype C Infection.

Item
http://www.wikidata.org/entity/Q34792976
HIV-1 envelope-receptor interactions required for macrophage infection and implications for current HIV-1 cure strategiesReliable genotypic tropism tests for the major HIV-1 subtypesi-bodies, Human Single Domain Antibodies That Antagonize Chemokine Receptor CXCR4.HIV-1 and SIV Predominantly Use CCR5 Expressed on a Precursor Population to Establish Infection in T Follicular Helper Cells.Coreceptor usage, diversity, and divergence in drug-naive and drug-exposed individuals from Malawi, infected with HIV-1 subtype C for more than 20 years.Distinct HIV-1 entry phenotypes are associated with transmission, subtype specificity, and resistance to broadly neutralizing antibodies.Differences in coreceptor specificity contribute to alternative tropism of HIV-1 subtype C for CD4(+) T-cell subsets, including stem cell memory T-cellsAlterations in HIV-1 gp120 V3 region are necessary but not sufficient for coreceptor switching in CRF07_BC in China.Covariance of charged amino acids at positions 322 and 440 of HIV-1 Env contributes to coreceptor specificity of subtype B viruses, and can be used to improve the performance of V3 sequence-based coreceptor usage prediction algorithms.Characteristics and spread to the native population of HIV-1 non-B subtypes in two European countries with high migration rateGenotypic Prediction of Co-receptor Tropism of HIV-1 Subtypes A and CLinkages between HIV-1 specificity for CCR5 or CXCR4 and in vitro usage of alternative coreceptors during progressive HIV-1 subtype C infection.Frequency and Env determinants of HIV-1 subtype C strains from antiretroviral therapy-naive subjects that display incomplete inhibition by maraviroc.Quantifying susceptibility of CD4+ stem memory T-cells to infection by laboratory adapted and clinical HIV-1 strains.A novel strategy to adapt SHIV-E1 carrying env from an RV144 volunteer to rhesus macaques: coreceptor switch and final recovery of a pathogenic virus with exclusive R5 tropism.Global phosphoproteomics of CCR5-tropic HIV-1 signaling reveals reprogramming of cellular protein production pathways and identifies p70-S6K1 and MK2 as HIV-responsive kinases required for optimal infection of CD4+ T cells.
P2860

Longitudinal Analysis of CCR5 and CXCR4 Usage in a Cohort of Antiretroviral Therapy-Naïve Subjects with Progressive HIV-1 Subtype C Infection.

Item
http://www.wikidata.org/entity/Q34792976
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Longitudinal Analysis of CCR5 ...... ive HIV-1 Subtype C Infection.
@ast
Longitudinal Analysis of CCR5 ...... ive HIV-1 Subtype C Infection.
@en
Longitudinal Analysis of CCR5 ...... ive HIV-1 Subtype C Infection.
@nl
type
label
Longitudinal Analysis of CCR5 ...... ive HIV-1 Subtype C Infection.
@ast
Longitudinal Analysis of CCR5 ...... ive HIV-1 Subtype C Infection.
@en
Longitudinal Analysis of CCR5 ...... ive HIV-1 Subtype C Infection.
@nl
prefLabel
Longitudinal Analysis of CCR5 ...... ive HIV-1 Subtype C Infection.
@ast
Longitudinal Analysis of CCR5 ...... ive HIV-1 Subtype C Infection.
@en
Longitudinal Analysis of CCR5 ...... ive HIV-1 Subtype C Infection.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932
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P1433
P1476
Longitudinal Analysis of CCR5 ...... sive HIV-1 Subtype C Infection
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0065950
P407
P433
P478
P50
P577
P5875
P698
P921
P932