Novel small-molecule inhibitors of Bcl-XL to treat lung cancer. - Wikidata - wikimedia - TriplyDB

Novel small-molecule inhibitors of Bcl-XL to treat lung cancer.

Novel small-molecule inhibitors of Bcl-XL to treat lung cancer.

http://www.wikidata.org/entity/Q34793542

about

Small-Molecule Bcl2 BH4 Antagonist for Lung Cancer Therapy Targeting BCL2-Proteins for the Treatment of Solid Tumours Restoration of mitochondria function as a target for cancer therapy Antitumor Activity of 2,9-Di-Sec-Butyl-1,10-Phenanthroline BM-1197: a novel and specific Bcl-2/Bcl-xL inhibitor inducing complete and long-lasting tumor regression in vivo Bcl-xL overexpression and its association with the progress of tongue carcinoma.Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel Identification of mRNA isoform switching in breast cancer.Radiosensitization by a novel Bcl-2 and Bcl-XL inhibitor S44563 in small-cell lung cancer.miR-504 mediated down-regulation of nuclear respiratory factor 1 leads to radio-resistance in nasopharyngeal carcinoma.Oncogenic miR-9 is a target of erlotinib in NSCLCs Targeting KRAS-mutant non-small cell lung cancer: challenges and opportunities.Killing Two Cells with One Stone: Pharmacologic BCL-2 Family Targeting for Cancer Cell Death and Immune Modulation.ABT-737 Synergizes with Cisplatin Bypassing Aberration of Apoptotic Pathway in Non-small Cell Lung Cancer.BCL2 Inhibitors as Anticancer Drugs: A Plethora of Misleading BH3 Mimetics.The influential role of BCL2 family members in synovial sarcomagenesis.MiR-9 is involved in TGF-β1-induced lung cancer cell invasion and adhesion by targeting SOX7.Systemic Delivery of Bc12-Targeting siRNA by DNA Nanoparticles Suppresses Cancer Cell Growth.Modulation of Bax and mTOR for Cancer Therapeutics.Conversion of MIG6 peptide from the nonbinder to binder of lung cancer-related EGFR by phosphorylation and cyclization.Pathways and mechanisms of venetoclax resistance.Bcl-2 family in non-small cell lung cancer: its prognostic and therapeutic implications.MicroRNA-29a induces apoptosis via increasing the Bax:Bcl-2 ratio in dermal fibroblasts of patients with systemic sclerosis.A dual-function epidermal growth factor receptor pathway substrate 8 (Eps8)-derived peptide exhibits a potent cytotoxic T lymphocyte-activating effect and a specific inhibitory activity.Antigen-specific primed cytotoxic T cells eliminate tumour cells in vivo and prevent tumour development, regardless of the presence of anti-apoptotic mutations conferring drug resistance.Role of Mitochondria-Associated ER Membranes in Calcium Regulation in Cancer-Specific Settings.Ceramide Metabolism Balance, a Multifaceted Factor in Critical Steps of Breast Cancer Development

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Novel small-molecule inhibitors of Bcl-XL to treat lung cancer.

http://www.wikidata.org/entity/Q34793542

description

2013 nî lūn-bûn

@nan

2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

Novel small-molecule inhibitors of Bcl-XL to treat lung cancer.

@ast

Novel small-molecule inhibitors of Bcl-XL to treat lung cancer.

@en

Novel small-molecule inhibitors of Bcl-XL to treat lung cancer.

@nl

type

label

Novel small-molecule inhibitors of Bcl-XL to treat lung cancer.

@ast

Novel small-molecule inhibitors of Bcl-XL to treat lung cancer.

@en

Novel small-molecule inhibitors of Bcl-XL to treat lung cancer.

@nl

prefLabel

Novel small-molecule inhibitors of Bcl-XL to treat lung cancer.

@ast

Novel small-molecule inhibitors of Bcl-XL to treat lung cancer.

@en

Novel small-molecule inhibitors of Bcl-XL to treat lung cancer.

@nl

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0008-5472.CAN-12-2272

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Cancer Research

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Novel small-molecule inhibitors of Bcl-XL to treat lung cancer

@en

P2093

Dongkyoo Park

http://www.w3.org/2001/XMLSchema#string

Fadlo R Khuri

http://www.w3.org/2001/XMLSchema#string

Gabriel L Sica

http://www.w3.org/2001/XMLSchema#string

Rui Li

http://www.w3.org/2001/XMLSchema#string

Shi-Yong Sun

http://www.w3.org/2001/XMLSchema#string

Suresh S Ramalingam

http://www.w3.org/2001/XMLSchema#string

Taofeek K Owonikoko

http://www.w3.org/2001/XMLSchema#string

Walter J Curran

http://www.w3.org/2001/XMLSchema#string

Xingming Deng

http://www.w3.org/2001/XMLSchema#string

P2860

The Hallmarks of Cancer

tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia

Bcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapy

Studies leading to potent, dual inhibitors of Bcl-2 and Bcl-xL

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

EGFR mutation and resistance of non-small-cell lung cancer to gefitinib.

Cancer statistics, 2010

Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening

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5485-5496

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scholarly article

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10.1158/0008-5472.CAN-12-2272

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17

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73

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3774010

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